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LINGO2 (leucine rich repeat and Ig domain containing 2)

Identity

Alias_namesLRRN6C
leucine rich repeat neuronal 6C
Alias_symbol (synonym)LERN3
Other alias
HGNC (Hugo) LINGO2
LocusID (NCBI) 158038
Atlas_Id 66111
Location 9p21.2  [Link to chromosome band 9p21]
Location_base_pair Starts at 27948086 and ends at 29213000 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MTAP (9p21.3) / LINGO2 (9p21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LINGO2   21207
Cards
Entrez_Gene (NCBI)LINGO2  158038  leucine rich repeat and Ig domain containing 2
AliasesLERN3; LRRN6C
GeneCards (Weizmann)LINGO2
Ensembl hg19 (Hinxton)ENSG00000174482 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174482 [Gene_View]  chr9:27948086-29213000 [Contig_View]  LINGO2 [Vega]
ICGC DataPortalENSG00000174482
TCGA cBioPortalLINGO2
AceView (NCBI)LINGO2
Genatlas (Paris)LINGO2
WikiGenes158038
SOURCE (Princeton)LINGO2
Genetics Home Reference (NIH)LINGO2
Genomic and cartography
GoldenPath hg38 (UCSC)LINGO2  -     chr9:27948086-29213000 -  9p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LINGO2  -     9p21.2   [Description]    (hg19-Feb_2009)
EnsemblLINGO2 - 9p21.2 [CytoView hg19]  LINGO2 - 9p21.2 [CytoView hg38]
Mapping of homologs : NCBILINGO2 [Mapview hg19]  LINGO2 [Mapview hg38]
OMIM609793   
Gene and transcription
Genbank (Entrez)AK056372 AK172834 AK290972 AY358114 BC137514
RefSeq transcript (Entrez)NM_001258282 NM_152570
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LINGO2
Cluster EST : UnigeneHs.745029 [ NCBI ]
CGAP (NCI)Hs.745029
Alternative Splicing GalleryENSG00000174482
Gene ExpressionLINGO2 [ NCBI-GEO ]   LINGO2 [ EBI - ARRAY_EXPRESS ]   LINGO2 [ SEEK ]   LINGO2 [ MEM ]
Gene Expression Viewer (FireBrowse)LINGO2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)158038
GTEX Portal (Tissue expression)LINGO2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7L985   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7L985  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7L985
Splice isoforms : SwissVarQ7L985
PhosPhoSitePlusQ7L985
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    LRR (PS51450)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)I-set (PF07679)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam07679    pfam13855   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  LRR_TYP (SM00369)  LRRNT (SM00013)  
Conserved Domain (NCBI)LINGO2
DMDM Disease mutations158038
Blocks (Seattle)LINGO2
SuperfamilyQ7L985
Human Protein AtlasENSG00000174482
Peptide AtlasQ7L985
HPRD08715
IPIIPI00001120   
Protein Interaction databases
DIP (DOE-UCLA)Q7L985
IntAct (EBI)Q7L985
FunCoupENSG00000174482
BioGRIDLINGO2
STRING (EMBL)LINGO2
ZODIACLINGO2
Ontologies - Pathways
QuickGOQ7L985
Ontology : AmiGOproteinaceous extracellular matrix  extracellular space  axonogenesis  integral component of membrane  positive regulation of synapse assembly  
Ontology : EGO-EBIproteinaceous extracellular matrix  extracellular space  axonogenesis  integral component of membrane  positive regulation of synapse assembly  
NDEx NetworkLINGO2
Atlas of Cancer Signalling NetworkLINGO2
Wikipedia pathwaysLINGO2
Orthology - Evolution
OrthoDB158038
GeneTree (enSembl)ENSG00000174482
Phylogenetic Trees/Animal Genes : TreeFamLINGO2
HOVERGENQ7L985
HOGENOMQ7L985
Homologs : HomoloGeneLINGO2
Homology/Alignments : Family Browser (UCSC)LINGO2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLINGO2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LINGO2
dbVarLINGO2
ClinVarLINGO2
1000_GenomesLINGO2 
Exome Variant ServerLINGO2
ExAC (Exome Aggregation Consortium)LINGO2 (select the gene name)
Genetic variants : HAPMAP158038
Genomic Variants (DGV)LINGO2 [DGVbeta]
DECIPHERLINGO2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLINGO2 
Mutations
ICGC Data PortalLINGO2 
TCGA Data PortalLINGO2 
Broad Tumor PortalLINGO2
OASIS PortalLINGO2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLINGO2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLINGO2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LINGO2
DgiDB (Drug Gene Interaction Database)LINGO2
DoCM (Curated mutations)LINGO2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LINGO2 (select a term)
intoGenLINGO2
Cancer3DLINGO2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609793   
Orphanet
MedgenLINGO2
Genetic Testing Registry LINGO2
NextProtQ7L985 [Medical]
TSGene158038
GENETestsLINGO2
Target ValidationLINGO2
Huge Navigator LINGO2 [HugePedia]
snp3D : Map Gene to Disease158038
BioCentury BCIQLINGO2
ClinGenLINGO2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD158038
Chemical/Pharm GKB GenePA162394096
Clinical trialLINGO2
Miscellaneous
canSAR (ICR)LINGO2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLINGO2
EVEXLINGO2
GoPubMedLINGO2
iHOPLINGO2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:16:40 CEST 2017

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