Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LIPC (lipase, hepatic)

Identity

Other namesHDLCQ12
HL
HTGL
LIPH
HGNC (Hugo) LIPC
LocusID (NCBI) 3990
Location 15q21.3
Location_base_pair Starts at 58724175 and ends at 58861073 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)LIPC   6619
Cards
Entrez_Gene (NCBI)LIPC  3990  lipase, hepatic
GeneCards (Weizmann)LIPC
Ensembl (Hinxton)ENSG00000166035 [Gene_View]  chr15:58724175-58861073 [Contig_View]  LIPC [Vega]
ICGC DataPortalENSG00000166035
cBioPortalLIPC
AceView (NCBI)LIPC
Genatlas (Paris)LIPC
WikiGenes3990
SOURCE (Princeton)NM_000236
Genomic and cartography
GoldenPath (UCSC)LIPC  -  15q21.3   chr15:58724175-58861073 +  15q21.3   [Description]    (hg19-Feb_2009)
EnsemblLIPC - 15q21.3 [CytoView]
Mapping of homologs : NCBILIPC [Mapview]
OMIM125853   151670   612797   614025   
Gene and transcription
Genbank (Entrez)AI823349 AK290062 AK292631 AK293324 AK309448
RefSeq transcript (Entrez)NM_000236
RefSeq genomic (Entrez)AC_000147 NC_000015 NC_018926 NG_011465 NT_010194 NW_001838218 NW_004929398
Consensus coding sequences : CCDS (NCBI)LIPC
Cluster EST : UnigeneHs.654472 [ NCBI ]
CGAP (NCI)Hs.654472
Alternative Splicing : Fast-db (Paris)GSHG0009896
Alternative Splicing GalleryENSG00000166035
Gene ExpressionLIPC [ NCBI-GEO ]     LIPC [ SEEK ]   LIPC [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11150 (Uniprot)
NextProtP11150  [Medical]
With graphics : InterProP11150
Splice isoforms : SwissVarP11150 (Swissvar)
Catalytic activity : Enzyme3.1.1.3 [ Enzyme-Expasy ]   3.1.1.33.1.1.3 [ IntEnz-EBI ]   3.1.1.3 [ BRENDA ]   3.1.1.3 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)LIPASE_SER (PS00120)    PLAT (PS50095)   
Domains : Interpro (EBI)AB_hydrolase [organisation]   Lipase [organisation]   Lipase_hep [organisation]   Lipase_LipOase [organisation]   Lipase_N [organisation]   Lipoprotein_lipase_LIPH [organisation]   PLAT/LH2_dom [organisation]  
Related proteins : CluSTrP11150
Domain families : Pfam (Sanger)Lipase (PF00151)    PLAT (PF01477)   
Domain families : Pfam (NCBI)pfam00151    pfam01477   
Domain families : Smart (EMBL)LH2 (SM00308)  
DMDM Disease mutations3990
Blocks (Seattle)P11150
Human Protein AtlasENSG00000166035 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP11150
HPRD01058
IPIIPI00003882   IPI00854588   IPI00909632   
Protein Interaction databases
DIP (DOE-UCLA)P11150
IntAct (EBI)P11150
FunCoupENSG00000166035
BioGRIDLIPC
InParanoidP11150
Interologous Interaction database P11150
IntegromeDBLIPC
STRING (EMBL)LIPC
Ontologies - Pathways
Ontology : AmiGOphospholipase activity  triglyceride lipase activity  extracellular space  fatty acid biosynthetic process  heparin binding  cholesterol metabolic process  triglyceride catabolic process  low-density lipoprotein particle binding  apolipoprotein binding  high-density lipoprotein particle  very-low-density lipoprotein particle remodeling  intermediate-density lipoprotein particle remodeling  low-density lipoprotein particle remodeling  high-density lipoprotein particle remodeling  chylomicron remnant clearance  phosphatidylcholine catabolic process  cholesterol homeostasis  reverse cholesterol transport  triglyceride homeostasis  
Ontology : EGO-EBIphospholipase activity  triglyceride lipase activity  extracellular space  fatty acid biosynthetic process  heparin binding  cholesterol metabolic process  triglyceride catabolic process  low-density lipoprotein particle binding  apolipoprotein binding  high-density lipoprotein particle  very-low-density lipoprotein particle remodeling  intermediate-density lipoprotein particle remodeling  low-density lipoprotein particle remodeling  high-density lipoprotein particle remodeling  chylomicron remnant clearance  phosphatidylcholine catabolic process  cholesterol homeostasis  reverse cholesterol transport  triglyceride homeostasis  
Pathways : KEGGGlycerolipid metabolism   
Protein Interaction DatabaseLIPC
Wikipedia pathwaysLIPC
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)LIPC
snp3D : Map Gene to Disease3990
SNP (GeneSNP Utah)LIPC
SNP : HGBaseLIPC
Genetic variants : HAPMAPLIPC
Exome VariantLIPC
1000_GenomesLIPC 
ICGC programENSG00000166035 
Somatic Mutations in Cancer : COSMICLIPC 
CONAN: Copy Number AnalysisLIPC 
Mutations and Diseases : HGMDLIPC
Mutations and Diseases : intOGenLIPC
Genomic VariantsLIPC  LIPC [DGVbeta]
dbVarLIPC
ClinVarLIPC
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM125853    151670    612797    614025   
MedgenLIPC
GENETestsLIPC
Disease Genetic AssociationLIPC
Huge Navigator LIPC [HugePedia]  LIPC [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneLIPC
Homology/Alignments : Family Browser (UCSC)LIPC
Phylogenetic Trees/Animal Genes : TreeFamLIPC
Chemical/Protein Interactions : CTD3990
Chemical/Pharm GKB GenePA230
Clinical trialLIPC
Cancer Resource (Charite)ENSG00000166035
Other databases
Probes
Litterature
PubMed291 Pubmed reference(s) in Entrez
CoreMineLIPC
iHOPLIPC
OncoSearchLIPC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:52:44 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.