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LIPE (lipase E, hormone sensitive type)

Identity

Alias_nameslipase
Alias_symbol (synonym)HSL
Other aliasAOMS4
FPLD6
LHS
HGNC (Hugo) LIPE
LocusID (NCBI) 3991
Atlas_Id 43466
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 42905659 and ends at 42931578 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LIPE (19q13.2) / CNFN (19q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LIPE   6621
Cards
Entrez_Gene (NCBI)LIPE  3991  lipase E, hormone sensitive type
AliasesAOMS4; FPLD6; HSL; LHS
GeneCards (Weizmann)LIPE
Ensembl hg19 (Hinxton)ENSG00000079435 [Gene_View]  chr19:42905659-42931578 [Contig_View]  LIPE [Vega]
Ensembl hg38 (Hinxton)ENSG00000079435 [Gene_View]  chr19:42905659-42931578 [Contig_View]  LIPE [Vega]
ICGC DataPortalENSG00000079435
TCGA cBioPortalLIPE
AceView (NCBI)LIPE
Genatlas (Paris)LIPE
WikiGenes3991
SOURCE (Princeton)LIPE
Genetics Home Reference (NIH)LIPE
Genomic and cartography
GoldenPath hg19 (UCSC)LIPE  -     chr19:42905659-42931578 -  19q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LIPE  -     19q13.2   [Description]    (hg38-Dec_2013)
EnsemblLIPE - 19q13.2 [CytoView hg19]  LIPE - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBILIPE [Mapview hg19]  LIPE [Mapview hg38]
OMIM151750   615980   
Gene and transcription
Genbank (Entrez)AK292482 AK309893 BC029301 BC029961 BC070041
RefSeq transcript (Entrez)NM_005357
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_034246 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)LIPE
Cluster EST : UnigeneHs.656980 [ NCBI ]
CGAP (NCI)Hs.656980
Alternative Splicing GalleryENSG00000079435
Gene ExpressionLIPE [ NCBI-GEO ]   LIPE [ EBI - ARRAY_EXPRESS ]   LIPE [ SEEK ]   LIPE [ MEM ]
Gene Expression Viewer (FireBrowse)LIPE [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3991
GTEX Portal (Tissue expression)LIPE
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ05469   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ05469  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ05469
Splice isoforms : SwissVarQ05469
PhosPhoSitePlusQ05469
Domaine pattern : Prosite (Expaxy)LIPASE_GDXG_HIS (PS01173)    LIPASE_GDXG_SER (PS01174)   
Domains : Interpro (EBI)AB_hydrolase    AB_hydrolase_3    HSL_N    Lipase_GDXG_HIS_AS    Lipase_GDXG_put_SER_AS   
Domain families : Pfam (Sanger)Abhydrolase_3 (PF07859)    HSL_N (PF06350)   
Domain families : Pfam (NCBI)pfam07859    pfam06350   
Conserved Domain (NCBI)LIPE
DMDM Disease mutations3991
Blocks (Seattle)LIPE
SuperfamilyQ05469
Human Protein AtlasENSG00000079435
Peptide AtlasQ05469
HPRD01062
IPIIPI00643204   IPI00419542   
Protein Interaction databases
DIP (DOE-UCLA)Q05469
IntAct (EBI)Q05469
FunCoupENSG00000079435
BioGRIDLIPE
STRING (EMBL)LIPE
ZODIACLIPE
Ontologies - Pathways
QuickGOQ05469
Ontology : AmiGOtriglyceride lipase activity  protein binding  lipid particle  cytosol  caveola  protein phosphorylation  cholesterol metabolic process  lipid catabolic process  triglyceride catabolic process  protein kinase binding  hormone-sensitive lipase activity  long-chain fatty acid catabolic process  diacylglycerol catabolic process  
Ontology : EGO-EBItriglyceride lipase activity  protein binding  lipid particle  cytosol  caveola  protein phosphorylation  cholesterol metabolic process  lipid catabolic process  triglyceride catabolic process  protein kinase binding  hormone-sensitive lipase activity  long-chain fatty acid catabolic process  diacylglycerol catabolic process  
Pathways : KEGGInsulin signaling pathway   
NDEx NetworkLIPE
Atlas of Cancer Signalling NetworkLIPE
Wikipedia pathwaysLIPE
Orthology - Evolution
OrthoDB3991
GeneTree (enSembl)ENSG00000079435
Phylogenetic Trees/Animal Genes : TreeFamLIPE
HOVERGENQ05469
HOGENOMQ05469
Homologs : HomoloGeneLIPE
Homology/Alignments : Family Browser (UCSC)LIPE
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLIPE [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LIPE
dbVarLIPE
ClinVarLIPE
1000_GenomesLIPE 
Exome Variant ServerLIPE
ExAC (Exome Aggregation Consortium)LIPE (select the gene name)
Genetic variants : HAPMAP3991
Genomic Variants (DGV)LIPE [DGVbeta]
DECIPHER (Syndromes)19:42905659-42931578  ENSG00000079435
CONAN: Copy Number AnalysisLIPE 
Mutations
ICGC Data PortalLIPE 
TCGA Data PortalLIPE 
Broad Tumor PortalLIPE
OASIS PortalLIPE [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLIPE  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLIPE
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LIPE
DgiDB (Drug Gene Interaction Database)LIPE
DoCM (Curated mutations)LIPE (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LIPE (select a term)
intoGenLIPE
Cancer3DLIPE(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM151750    615980   
Orphanet23310   
MedgenLIPE
Genetic Testing Registry LIPE
NextProtQ05469 [Medical]
TSGene3991
GENETestsLIPE
Huge Navigator LIPE [HugePedia]
snp3D : Map Gene to Disease3991
BioCentury BCIQLIPE
ClinGenLIPE
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3991
Chemical/Pharm GKB GenePA30393
Clinical trialLIPE
Miscellaneous
canSAR (ICR)LIPE (select the gene name)
Probes
Litterature
PubMed96 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLIPE
EVEXLIPE
GoPubMedLIPE
iHOPLIPE
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:07:11 CEST 2017

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