LIPF (lipase F, gastric type)

2010-03-01  

Identity

HGNC
LOCATION
10q23.31
LOCUSID
ALIAS
GL,HGL,HLAL
FUSION GENES

Other Information

Locus ID:

NCBI: 8513
MIM: 601980
HGNC: 6622
Ensembl: ENSG00000182333

Variants:

dbSNP: 8513
ClinVar: 8513
TCGA: ENSG00000182333
COSMIC: LIPF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182333ENST00000238983P07098
ENSG00000182333ENST00000355843P07098
ENSG00000182333ENST00000394375P07098
ENSG00000182333ENST00000608620P07098

Expression (GTEx)

0
5000
10000
15000
20000
25000
30000

Pathways

PathwaySourceExternal ID
Glycerolipid metabolismKEGGko00561
Glycerolipid metabolismKEGGhsa00561
Metabolic pathwaysKEGGhsa01100
Fat digestion and absorptionKEGGko04975
Fat digestion and absorptionKEGGhsa04975
Acylglycerol degradationKEGGhsa_M00098
Acylglycerol degradationKEGGM00098
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Digestion of dietary lipidREACTOMER-HSA-192456

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
200430752010An 8-gene signature, including methylated and down-regulated glutathione peroxidase 3, of gastric cancer.24
189961022009Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.11
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
119406042002Mechanisms of inhibition of triacylglycerol hydrolysis by human gastric lipase.7
186817812008Genetic correlates of olanzapine-induced weight gain in schizophrenia subjects from north India: role of metabolic pathway genes.7
219457022012Expression of active recombinant human gastric lipase in Nicotiana benthamiana using the CPMV-HT transient expression system.6
208853902011A common haplotype in NAPEPLD is associated with severe obesity in a Norwegian population-based cohort (the HUNT study).5
209651712010Molecular dynamics simulations of human and dog gastric lipases: insights into domain movements.4

Citation

Dessen P

LIPF (lipase F, gastric type)

Atlas Genet Cytogenet Oncol Haematol. 2010-03-01

Online version: http://atlasgeneticsoncology.org/gene/51382/lipf