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LMF1 (lipase maturation factor 1)

Identity

Alias_namesC16orf26
TMEM112
chromosome 16 open reading frame 26
transmembrane protein 112
Alias_symbol (synonym)FLJ12681
JFP11
FLJ22302
TMEM112A
Other aliasHMFN1876
HGNC (Hugo) LMF1
LocusID (NCBI) 64788
Atlas_Id 54425
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 903635 and ends at 1020984 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BCL7C (16p11.2) / LMF1 (16p13.3)CENPBD1 (16q24.3) / LMF1 (16p13.3)KIF21A (12q12) / LMF1 (16p13.3)
LMF1 (16p13.3) / BZRAP1 (17q22)LMF1 (16p13.3) / KLC2 (11q13.2)LMF1 (16p13.3) / UMOD (16p12.3)
PDXDC1 (16p13.11) / LMF1 (16p13.3)KIF21A 12q12 / LMF1 16p13.3PDXDC1 16p13.11 / LMF1 16p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LMF1   14154
Cards
Entrez_Gene (NCBI)LMF1  64788  lipase maturation factor 1
AliasesC16orf26; HMFN1876; JFP11; TMEM112; 
TMEM112A
GeneCards (Weizmann)LMF1
Ensembl hg19 (Hinxton)ENSG00000103227 [Gene_View]  chr16:903635-1020984 [Contig_View]  LMF1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000103227 [Gene_View]  chr16:903635-1020984 [Contig_View]  LMF1 [Vega]
ICGC DataPortalENSG00000103227
TCGA cBioPortalLMF1
AceView (NCBI)LMF1
Genatlas (Paris)LMF1
WikiGenes64788
SOURCE (Princeton)LMF1
Genetics Home Reference (NIH)LMF1
Genomic and cartography
GoldenPath hg19 (UCSC)LMF1  -     chr16:903635-1020984 -  16p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LMF1  -     16p13.3   [Description]    (hg38-Dec_2013)
EnsemblLMF1 - 16p13.3 [CytoView hg19]  LMF1 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBILMF1 [Mapview hg19]  LMF1 [Mapview hg38]
OMIM246650   611761   
Gene and transcription
Genbank (Entrez)AB075873 AK022743 AK025955 AK093050 AK125201
RefSeq transcript (Entrez)NM_022773
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_021286 NT_010393 NW_004929400
Consensus coding sequences : CCDS (NCBI)LMF1
Cluster EST : UnigeneHs.745022 [ NCBI ]
CGAP (NCI)Hs.745022
Alternative Splicing GalleryENSG00000103227
Gene ExpressionLMF1 [ NCBI-GEO ]   LMF1 [ EBI - ARRAY_EXPRESS ]   LMF1 [ SEEK ]   LMF1 [ MEM ]
Gene Expression Viewer (FireBrowse)LMF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64788
GTEX Portal (Tissue expression)LMF1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96S06   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96S06  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96S06
Splice isoforms : SwissVarQ96S06
PhosPhoSitePlusQ96S06
Domains : Interpro (EBI)LMF   
Domain families : Pfam (Sanger)LMF1 (PF06762)   
Domain families : Pfam (NCBI)pfam06762   
Conserved Domain (NCBI)LMF1
DMDM Disease mutations64788
Blocks (Seattle)LMF1
SuperfamilyQ96S06
Human Protein AtlasENSG00000103227
Peptide AtlasQ96S06
HPRD07789
IPIIPI00304223   IPI00646812   IPI00908834   IPI01010678   IPI01014426   IPI01014347   IPI00829647   IPI00878737   
Protein Interaction databases
DIP (DOE-UCLA)Q96S06
IntAct (EBI)Q96S06
FunCoupENSG00000103227
BioGRIDLMF1
STRING (EMBL)LMF1
ZODIACLMF1
Ontologies - Pathways
QuickGOQ96S06
Ontology : AmiGOendoplasmic reticulum membrane  Golgi apparatus  ER to Golgi vesicle-mediated transport  protein secretion  integral component of membrane  protein glycosylation in Golgi  chylomicron remnant clearance  lipid digestion  positive regulation of lipoprotein lipase activity  protein maturation  regulation of cholesterol metabolic process  regulation of triglyceride metabolic process  
Ontology : EGO-EBIendoplasmic reticulum membrane  Golgi apparatus  ER to Golgi vesicle-mediated transport  protein secretion  integral component of membrane  protein glycosylation in Golgi  chylomicron remnant clearance  lipid digestion  positive regulation of lipoprotein lipase activity  protein maturation  regulation of cholesterol metabolic process  regulation of triglyceride metabolic process  
NDEx NetworkLMF1
Atlas of Cancer Signalling NetworkLMF1
Wikipedia pathwaysLMF1
Orthology - Evolution
OrthoDB64788
GeneTree (enSembl)ENSG00000103227
Phylogenetic Trees/Animal Genes : TreeFamLMF1
HOVERGENQ96S06
HOGENOMQ96S06
Homologs : HomoloGeneLMF1
Homology/Alignments : Family Browser (UCSC)LMF1
Gene fusions - Rearrangements
Fusion : MitelmanKIF21A/LMF1 [12q12/16p13.3]  [t(12;16)(q12;p13)]  
Fusion : MitelmanLMF1/UMOD [16p13.3/16p12.3]  [t(16;16)(p12;p13)]  
Fusion : MitelmanPDXDC1/LMF1 [16p13.11/16p13.3]  [t(16;16)(p13;p13)]  
Fusion: TCGAKIF21A 12q12 LMF1 16p13.3 LUAD
Fusion: TCGAPDXDC1 16p13.11 LMF1 16p13.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLMF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LMF1
dbVarLMF1
ClinVarLMF1
1000_GenomesLMF1 
Exome Variant ServerLMF1
ExAC (Exome Aggregation Consortium)LMF1 (select the gene name)
Genetic variants : HAPMAP64788
Genomic Variants (DGV)LMF1 [DGVbeta]
DECIPHER (Syndromes)16:903635-1020984  ENSG00000103227
CONAN: Copy Number AnalysisLMF1 
Mutations
ICGC Data PortalLMF1 
TCGA Data PortalLMF1 
Broad Tumor PortalLMF1
OASIS PortalLMF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLMF1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLMF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LMF1
DgiDB (Drug Gene Interaction Database)LMF1
DoCM (Curated mutations)LMF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LMF1 (select a term)
intoGenLMF1
Cancer3DLMF1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM246650    611761   
Orphanet23491   
MedgenLMF1
Genetic Testing Registry LMF1
NextProtQ96S06 [Medical]
TSGene64788
GENETestsLMF1
Huge Navigator LMF1 [HugePedia]
snp3D : Map Gene to Disease64788
BioCentury BCIQLMF1
ClinGenLMF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64788
Chemical/Pharm GKB GenePA25540
Clinical trialLMF1
Miscellaneous
canSAR (ICR)LMF1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLMF1
EVEXLMF1
GoPubMedLMF1
iHOPLMF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:07:13 CEST 2017

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