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LMLN (leishmanolysin like peptidase)

Identity

Alias_namesleishmanolysin-like (metallopeptidase M8 family)
Alias_symbol (synonym)Gp63
Msp
Other aliasGP63
INV
IX14
MSP
HGNC (Hugo) LMLN
LocusID (NCBI) 89782
Atlas_Id 66139
Location 3q29  [Link to chromosome band 3q29]
Location_base_pair Starts at 197960200 and ends at 198043720 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LMLN   15991
Cards
Entrez_Gene (NCBI)LMLN  89782  leishmanolysin like peptidase
AliasesGP63; INV; IX14; MSP
GeneCards (Weizmann)LMLN
Ensembl hg19 (Hinxton)ENSG00000185621 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185621 [Gene_View]  chr3:197960200-198043720 [Contig_View]  LMLN [Vega]
ICGC DataPortalENSG00000185621
TCGA cBioPortalLMLN
AceView (NCBI)LMLN
Genatlas (Paris)LMLN
WikiGenes89782
SOURCE (Princeton)LMLN
Genetics Home Reference (NIH)LMLN
Genomic and cartography
GoldenPath hg38 (UCSC)LMLN  -     chr3:197960200-198043720 +  3q29   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LMLN  -     3q29   [Description]    (hg19-Feb_2009)
EnsemblLMLN - 3q29 [CytoView hg19]  LMLN - 3q29 [CytoView hg38]
Mapping of homologs : NCBILMLN [Mapview hg19]  LMLN [Mapview hg38]
OMIM609380   
Gene and transcription
Genbank (Entrez)AI967988 AJ312398 AJ312399 AK299119 AL832783
RefSeq transcript (Entrez)NM_001136049 NM_033029
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LMLN
Cluster EST : UnigeneHs.518540 [ NCBI ]
CGAP (NCI)Hs.518540
Alternative Splicing GalleryENSG00000185621
Gene ExpressionLMLN [ NCBI-GEO ]   LMLN [ EBI - ARRAY_EXPRESS ]   LMLN [ SEEK ]   LMLN [ MEM ]
Gene Expression Viewer (FireBrowse)LMLN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)89782
GTEX Portal (Tissue expression)LMLN
Human Protein AtlasENSG00000185621-LMLN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96KR4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96KR4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96KR4
Splice isoforms : SwissVarQ96KR4
Catalytic activity : Enzyme3.4.24.- [ Enzyme-Expasy ]   3.4.24.-3.4.24.- [ IntEnz-EBI ]   3.4.24.- [ BRENDA ]   3.4.24.- [ KEGG ]   
PhosPhoSitePlusQ96KR4
Domains : Interpro (EBI)Peptidase_M8   
Domain families : Pfam (Sanger)Peptidase_M8 (PF01457)   
Domain families : Pfam (NCBI)pfam01457   
Conserved Domain (NCBI)LMLN
DMDM Disease mutations89782
Blocks (Seattle)LMLN
SuperfamilyQ96KR4
Human Protein Atlas [tissue]ENSG00000185621-LMLN [tissue]
Peptide AtlasQ96KR4
HPRD07023
IPIIPI00064741   IPI00903090   IPI00924964   IPI00925115   IPI00925294   
Protein Interaction databases
DIP (DOE-UCLA)Q96KR4
IntAct (EBI)Q96KR4
FunCoupENSG00000185621
BioGRIDLMLN
STRING (EMBL)LMLN
ZODIACLMLN
Ontologies - Pathways
QuickGOQ96KR4
Ontology : AmiGOmetalloendopeptidase activity  lipid particle  cytosol  focal adhesion  proteolysis  cell cycle  cell adhesion  membrane  metal ion binding  cell division  
Ontology : EGO-EBImetalloendopeptidase activity  lipid particle  cytosol  focal adhesion  proteolysis  cell cycle  cell adhesion  membrane  metal ion binding  cell division  
NDEx NetworkLMLN
Atlas of Cancer Signalling NetworkLMLN
Wikipedia pathwaysLMLN
Orthology - Evolution
OrthoDB89782
GeneTree (enSembl)ENSG00000185621
Phylogenetic Trees/Animal Genes : TreeFamLMLN
HOVERGENQ96KR4
HOGENOMQ96KR4
Homologs : HomoloGeneLMLN
Homology/Alignments : Family Browser (UCSC)LMLN
Gene fusions - Rearrangements
Tumor Fusion PortalLMLN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLMLN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LMLN
dbVarLMLN
ClinVarLMLN
1000_GenomesLMLN 
Exome Variant ServerLMLN
ExAC (Exome Aggregation Consortium)ENSG00000185621
GNOMAD BrowserENSG00000185621
Genetic variants : HAPMAP89782
Genomic Variants (DGV)LMLN [DGVbeta]
DECIPHERLMLN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLMLN 
Mutations
ICGC Data PortalLMLN 
TCGA Data PortalLMLN 
Broad Tumor PortalLMLN
OASIS PortalLMLN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLMLN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLMLN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LMLN
DgiDB (Drug Gene Interaction Database)LMLN
DoCM (Curated mutations)LMLN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LMLN (select a term)
intoGenLMLN
Cancer3DLMLN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609380   
Orphanet
DisGeNETLMLN
MedgenLMLN
Genetic Testing Registry LMLN
NextProtQ96KR4 [Medical]
TSGene89782
GENETestsLMLN
Target ValidationLMLN
Huge Navigator LMLN [HugePedia]
snp3D : Map Gene to Disease89782
BioCentury BCIQLMLN
ClinGenLMLN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD89782
Chemical/Pharm GKB GenePA30402
Clinical trialLMLN
Miscellaneous
canSAR (ICR)LMLN (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLMLN
EVEXLMLN
GoPubMedLMLN
iHOPLMLN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:08:11 CET 2017

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