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LMNB2 (lamin B2)

Identity

Alias_namesLMN2
Other aliasEPM9
LAMB2
HGNC (Hugo) LMNB2
LocusID (NCBI) 84823
Atlas_Id 66141
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 2428165 and ends at 2456968 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LMNB2 (19p13.3) / GNG7 (19p13.3)PSME3 (17q21.31) / LMNB2 (19p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LMNB2   6638
Cards
Entrez_Gene (NCBI)LMNB2  84823  lamin B2
AliasesEPM9; LAMB2; LMN2
GeneCards (Weizmann)LMNB2
Ensembl hg19 (Hinxton)ENSG00000176619 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176619 [Gene_View]  chr19:2428165-2456968 [Contig_View]  LMNB2 [Vega]
ICGC DataPortalENSG00000176619
TCGA cBioPortalLMNB2
AceView (NCBI)LMNB2
Genatlas (Paris)LMNB2
WikiGenes84823
SOURCE (Princeton)LMNB2
Genetics Home Reference (NIH)LMNB2
Genomic and cartography
GoldenPath hg38 (UCSC)LMNB2  -     chr19:2428165-2456968 -  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LMNB2  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblLMNB2 - 19p13.3 [CytoView hg19]  LMNB2 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBILMNB2 [Mapview hg19]  LMNB2 [Mapview hg38]
OMIM150341   608709   616540   
Gene and transcription
Genbank (Entrez)AK129641 AL560944 BC006513 BC006551 BC009267
RefSeq transcript (Entrez)NM_032737
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LMNB2
Cluster EST : UnigeneHs.538286 [ NCBI ]
CGAP (NCI)Hs.538286
Alternative Splicing GalleryENSG00000176619
Gene ExpressionLMNB2 [ NCBI-GEO ]   LMNB2 [ EBI - ARRAY_EXPRESS ]   LMNB2 [ SEEK ]   LMNB2 [ MEM ]
Gene Expression Viewer (FireBrowse)LMNB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84823
GTEX Portal (Tissue expression)LMNB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ03252   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ03252  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ03252
Splice isoforms : SwissVarQ03252
PhosPhoSitePlusQ03252
Domaine pattern : Prosite (Expaxy)IF (PS00226)   
Domains : Interpro (EBI)IF    Intermediate_filament_CS    Lamin_tail_dom   
Domain families : Pfam (Sanger)Filament (PF00038)    LTD (PF00932)   
Domain families : Pfam (NCBI)pfam00038    pfam00932   
Domain families : Smart (EMBL)Filament (SM01391)  
Conserved Domain (NCBI)LMNB2
DMDM Disease mutations84823
Blocks (Seattle)LMNB2
PDB (SRS)2LLL    5BNW   
PDB (PDBSum)2LLL    5BNW   
PDB (IMB)2LLL    5BNW   
PDB (RSDB)2LLL    5BNW   
Structural Biology KnowledgeBase2LLL    5BNW   
SCOP (Structural Classification of Proteins)2LLL    5BNW   
CATH (Classification of proteins structures)2LLL    5BNW   
SuperfamilyQ03252
Human Protein AtlasENSG00000176619
Peptide AtlasQ03252
HPRD01037
IPIIPI00009771   
Protein Interaction databases
DIP (DOE-UCLA)Q03252
IntAct (EBI)Q03252
FunCoupENSG00000176619
BioGRIDLMNB2
STRING (EMBL)LMNB2
ZODIACLMNB2
Ontologies - Pathways
QuickGOQ03252
Ontology : AmiGOmolecular_function  structural molecule activity  nuclear inner membrane  lamin filament  biological_process  
Ontology : EGO-EBImolecular_function  structural molecule activity  nuclear inner membrane  lamin filament  biological_process  
Pathways : BIOCARTACaspase Cascade in Apoptosis [Genes]    TNFR1 Signaling Pathway [Genes]    FAS signaling pathway ( CD95 ) [Genes]    HIV-I Nef: negative effector of Fas and TNF [Genes]   
NDEx NetworkLMNB2
Atlas of Cancer Signalling NetworkLMNB2
Wikipedia pathwaysLMNB2
Orthology - Evolution
OrthoDB84823
GeneTree (enSembl)ENSG00000176619
Phylogenetic Trees/Animal Genes : TreeFamLMNB2
HOVERGENQ03252
HOGENOMQ03252
Homologs : HomoloGeneLMNB2
Homology/Alignments : Family Browser (UCSC)LMNB2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLMNB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LMNB2
dbVarLMNB2
ClinVarLMNB2
1000_GenomesLMNB2 
Exome Variant ServerLMNB2
ExAC (Exome Aggregation Consortium)LMNB2 (select the gene name)
Genetic variants : HAPMAP84823
Genomic Variants (DGV)LMNB2 [DGVbeta]
DECIPHERLMNB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLMNB2 
Mutations
ICGC Data PortalLMNB2 
TCGA Data PortalLMNB2 
Broad Tumor PortalLMNB2
OASIS PortalLMNB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLMNB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLMNB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LMNB2
DgiDB (Drug Gene Interaction Database)LMNB2
DoCM (Curated mutations)LMNB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LMNB2 (select a term)
intoGenLMNB2
Cancer3DLMNB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM150341    608709    616540   
Orphanet23718    11131   
MedgenLMNB2
Genetic Testing Registry LMNB2
NextProtQ03252 [Medical]
TSGene84823
GENETestsLMNB2
Target ValidationLMNB2
Huge Navigator LMNB2 [HugePedia]
snp3D : Map Gene to Disease84823
BioCentury BCIQLMNB2
ClinGenLMNB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84823
Chemical/Pharm GKB GenePA30404
Clinical trialLMNB2
Miscellaneous
canSAR (ICR)LMNB2 (select the gene name)
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLMNB2
EVEXLMNB2
GoPubMedLMNB2
iHOPLMNB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:16:46 CEST 2017

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