LMOD2 (leiomodin 2)

2016-08-01  

Identity

HGNC
LOCATION
7q31.32
LOCUSID
ALIAS
C-LMOD,CLMOD
FUSION GENES

Other Information

Locus ID:

NCBI: 442721
MIM: 608006
HGNC: 6648
Ensembl: ENSG00000170807

Variants:

dbSNP: 442721
ClinVar: 442721
TCGA: ENSG00000170807
COSMIC: LMOD2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170807ENST00000456238C9J8F4
ENSG00000170807ENST00000458573Q6P5Q4

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
166331402006Risperidone-related weight gain: genetic and nongenetic predictors.26
268732452016Localization of the binding interface between leiomodin-2 and α-tropomyosin.8
184037132008Leiomodin is an actin filament nucleator in muscle cells.0
263700582015How Leiomodin and Tropomodulin use a common fold for different actin assembly functions.0
264170722015Mechanisms of leiomodin 2-mediated regulation of actin filament in muscle cells.0
288347252017Crystal Structure of Leiomodin 2 in Complex with Actin: A Structural and Functional Reexamination.0
315170522019Disruption of cardiac thin filament assembly arising from a mutation in LMOD2: A novel mechanism of neonatal dilated cardiomyopathy.0

Citation

Dessen P

LMOD2 (leiomodin 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55840/lmod2