Atlas of Genetics and Cytogenetics in Oncology and Haematology


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LMTK3 (lemur tyrosine kinase 3)

Identity

Alias_namesregulatory subunit 101
Alias_symbol (synonym)KIAA1883
LMR3
TYKLM3
PPP1R101
Other alias
HGNC (Hugo) LMTK3
LocusID (NCBI) 114783
Atlas_Id 43602
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 48988528 and ends at 49016446 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LMTK3 (19q13.33) / LMTK3 (19q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LMTK3   19295
Cards
Entrez_Gene (NCBI)LMTK3  114783  lemur tyrosine kinase 3
AliasesLMR3; PPP1R101; TYKLM3
GeneCards (Weizmann)LMTK3
Ensembl hg19 (Hinxton)ENSG00000142235 [Gene_View]  chr19:48988528-49016446 [Contig_View]  LMTK3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000142235 [Gene_View]  chr19:48988528-49016446 [Contig_View]  LMTK3 [Vega]
ICGC DataPortalENSG00000142235
TCGA cBioPortalLMTK3
AceView (NCBI)LMTK3
Genatlas (Paris)LMTK3
WikiGenes114783
SOURCE (Princeton)LMTK3
Genetics Home Reference (NIH)LMTK3
Genomic and cartography
GoldenPath hg19 (UCSC)LMTK3  -     chr19:48988528-49016446 -  19q13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LMTK3  -     19q13.33   [Description]    (hg38-Dec_2013)
EnsemblLMTK3 - 19q13.33 [CytoView hg19]  LMTK3 - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBILMTK3 [Mapview hg19]  LMTK3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB067470 BC036690
RefSeq transcript (Entrez)NM_001080434
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)LMTK3
Cluster EST : UnigeneHs.207426 [ NCBI ]
CGAP (NCI)Hs.207426
Alternative Splicing GalleryENSG00000142235
Gene ExpressionLMTK3 [ NCBI-GEO ]   LMTK3 [ EBI - ARRAY_EXPRESS ]   LMTK3 [ SEEK ]   LMTK3 [ MEM ]
Gene Expression Viewer (FireBrowse)LMTK3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114783
GTEX Portal (Tissue expression)LMTK3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96Q04   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96Q04  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96Q04
Splice isoforms : SwissVarQ96Q04
PhosPhoSitePlusQ96Q04
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_TYR (PS00109)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser-Thr/Tyr_kinase_cat_dom    Tyr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase_Tyr (PF07714)   
Domain families : Pfam (NCBI)pfam07714   
Conserved Domain (NCBI)LMTK3
DMDM Disease mutations114783
Blocks (Seattle)LMTK3
SuperfamilyQ96Q04
Human Protein AtlasENSG00000142235
Peptide AtlasQ96Q04
IPIIPI00140833   
Protein Interaction databases
DIP (DOE-UCLA)Q96Q04
IntAct (EBI)Q96Q04
FunCoupENSG00000142235
BioGRIDLMTK3
STRING (EMBL)LMTK3
ZODIACLMTK3
Ontologies - Pathways
QuickGOQ96Q04
Ontology : AmiGOGolgi membrane  molecular_function  protein serine/threonine kinase activity  ATP binding  cellular_component  protein phosphorylation  negative regulation of phosphatase activity  integral component of membrane  axon  dendrite  metal ion binding  
Ontology : EGO-EBIGolgi membrane  molecular_function  protein serine/threonine kinase activity  ATP binding  cellular_component  protein phosphorylation  negative regulation of phosphatase activity  integral component of membrane  axon  dendrite  metal ion binding  
NDEx NetworkLMTK3
Atlas of Cancer Signalling NetworkLMTK3
Wikipedia pathwaysLMTK3
Orthology - Evolution
OrthoDB114783
GeneTree (enSembl)ENSG00000142235
Phylogenetic Trees/Animal Genes : TreeFamLMTK3
HOVERGENQ96Q04
HOGENOMQ96Q04
Homologs : HomoloGeneLMTK3
Homology/Alignments : Family Browser (UCSC)LMTK3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLMTK3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LMTK3
dbVarLMTK3
ClinVarLMTK3
1000_GenomesLMTK3 
Exome Variant ServerLMTK3
ExAC (Exome Aggregation Consortium)LMTK3 (select the gene name)
Genetic variants : HAPMAP114783
Genomic Variants (DGV)LMTK3 [DGVbeta]
DECIPHER (Syndromes)19:48988528-49016446  ENSG00000142235
CONAN: Copy Number AnalysisLMTK3 
Mutations
ICGC Data PortalLMTK3 
TCGA Data PortalLMTK3 
Broad Tumor PortalLMTK3
OASIS PortalLMTK3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLMTK3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLMTK3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LMTK3
DgiDB (Drug Gene Interaction Database)LMTK3
DoCM (Curated mutations)LMTK3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LMTK3 (select a term)
intoGenLMTK3
Cancer3DLMTK3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenLMTK3
Genetic Testing Registry LMTK3
NextProtQ96Q04 [Medical]
TSGene114783
GENETestsLMTK3
Huge Navigator LMTK3 [HugePedia]
snp3D : Map Gene to Disease114783
BioCentury BCIQLMTK3
ClinGenLMTK3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114783
Chemical/Pharm GKB GenePA134951789
Clinical trialLMTK3
Miscellaneous
canSAR (ICR)LMTK3 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLMTK3
EVEXLMTK3
GoPubMedLMTK3
iHOPLMTK3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:07:15 CEST 2017

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