Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LNX1 (ligand of numb-protein X 1, E3 ubiquitin protein ligase)

Identity

Other namesLNX
MPDZ
PDZRN2
HGNC (Hugo) LNX1
LocusID (NCBI) 84708
Location 4q12
Location_base_pair Starts at 54326437 and ends at 54457753 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LNX1   6657
Entrez_Gene (NCBI)LNX1  84708  ligand of numb-protein X 1, E3 ubiquitin protein ligase
Cards
GeneCards (Weizmann)LNX1
Ensembl (Hinxton)ENSG00000072201 [Gene_View]  chr4:54326437-54457753 [Contig_View]  LNX1 [Vega]
AceView (NCBI)LNX1
Genatlas (Paris)LNX1
SOURCE (Stanford)NM_001126328 NM_032622
Genomic and cartography
GoldenPath (UCSC)LNX1  -  4q12   chr4:54326437-54457753 -  4q12   [Description]    (hg19-Feb_2009)
EnsemblLNX1 - 4q12 [CytoView]
Mapping of homologs : NCBILNX1 [Mapview]
OMIM609732   
Gene and transcription
Genbank (Entrez)AF237782 AK056823 AK294611 AY358326 BC022983
RefSeq transcript (SRS)NM_001126328 NM_032622
RefSeq transcript (Entrez)NM_001126328 NM_032622
RefSeq genomic (SRS)AC_000136 NC_000004 NC_018915 NT_022853 NW_001838913 NW_004078020
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_022853 NW_001838913 NW_004078020
Consensus coding sequences : CCDS (NCBI)LNX1
Cluster EST : UnigeneHs.518760 [ SRS ] Hs.518760 [ NCBI ]
CGAP (NCI)Hs.518760
Alternative Splicing : Fast-db (Paris)GSHG0023253
Alternative Splicing GalleryENSG00000072201
Gene ExpressionLNX1 [ NCBI-GEO ]   LNX1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TBB1 (SRS) Q8TBB1 (Uniprot)
NextProtQ8TBB1
With graphics : InterProQ8TBB1
Splice isoforms : SwissVarQ8TBB1(Swissvar)
Domaine pattern : Prosite (SRS)PDZ (PS50106)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domaine pattern : Prosite (Expaxy)PDZ (PS50106)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (SRS)PDZ    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domains : Interpro (EBI)PDZ    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Related proteins : CluSTrQ8TBB1
Domain families : Pfam (SRS)PDZ (PF00595)   
Domain families : Pfam (Sanger)PDZ (PF00595)   
Domain families : Pfam (NCBI)pfam00595   
Domain families : Smart (EMBL)PDZ (SM00228)  RING (SM00184)  
DMDM84708
Blocks (Seattle)Q8TBB1
PDB (SRS)3B76   
PDB (PDBSum)3B76   
PDB (IMB)3B76   
PDB (RSDB)3B76   
Human Protein AtlasENSG00000072201
HPRD17287
IPIIPI00152181   IPI00305598   IPI01009666   IPI00967553   IPI00967288   IPI00968256   IPI00966985   IPI00968006   
Protein Interaction databases
DIP (DOE-UCLA)Q8TBB1
IntAct (EBI)Q8TBB1
FunCoupENSG00000072201
REACTOMELNX1
Protein Interaction Database84708
BioGRIDLNX1
InParanoidQ8TBB1
Interologous Interaction database Q8TBB1
IntegromeDBLNX1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)LNX1
SNP (GeneSNP Utah)LNX1
SNP : HGBaseLNX1
Genetic variants : HAPMAPLNX1
Somatic Mutations in Cancer : COSMICLNX1 
CONAN: Copy Number AnalysisLNX1 
Mutations and Diseases : HGMDLNX1
OMIM609732   
GENETests609732   
Disease Genetic AssociationLNX1
Huge Navigator LNX1 [HugePedia]  LNX1 [HugeCancerGEM]
Genomic VariantsLNX1  LNX1 [DGVbeta]
snp3D : Map Gene to Disease84708
General knowledge
Homologs : HomoloGeneLNX1
Homology/Alignments : Family Browser (UCSC)LNX1
Phylogenetic Trees/Animal Genes : TreeFamLNX1
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.- [ Enzyme-SRS ]   6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
Chemical/Protein Interactions : CTD84708
Chemical/Pharm GKB GenePA30419
Clinical trialLNX1
Cancer Resource (Charite)ENSG00000072201
Ontology : AmiGOubiquitin-protein ligase activity  protein binding  cytoplasm  zinc ion binding  PDZ domain binding  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  metal ion binding  protein homooligomerization  
Ontology : EGO-EBIubiquitin-protein ligase activity  protein binding  cytoplasm  zinc ion binding  PDZ domain binding  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  metal ion binding  protein homooligomerization  
Pathways : KEGGTryptophan metabolism
Other databases
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
PubGeneLNX1
iHOPLNX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:38:45 CEST 2013
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.