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LOR (loricrin)

Identity

Other alias-
HGNC (Hugo) LOR
LocusID (NCBI) 4014
Atlas_Id 56547
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 153259703 and ends at 153262124 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LOR   6663
Cards
Entrez_Gene (NCBI)LOR  4014  loricrin
Aliases
GeneCards (Weizmann)LOR
Ensembl hg19 (Hinxton)ENSG00000203782 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000203782 [Gene_View]  ENSG00000203782 [Sequence]  chr1:153259703-153262124 [Contig_View]  LOR [Vega]
ICGC DataPortalENSG00000203782
TCGA cBioPortalLOR
AceView (NCBI)LOR
Genatlas (Paris)LOR
WikiGenes4014
SOURCE (Princeton)LOR
Genetics Home Reference (NIH)LOR
Genomic and cartography
GoldenPath hg38 (UCSC)LOR  -     chr1:153259703-153262124 +  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LOR  -     1q21.3   [Description]    (hg19-Feb_2009)
EnsemblLOR - 1q21.3 [CytoView hg19]  LOR - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBILOR [Mapview hg19]  LOR [Mapview hg38]
OMIM152445   604117   
Gene and transcription
Genbank (Entrez)BC034690 BC108290 CR536555 M61120
RefSeq transcript (Entrez)NM_000427
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LOR
Cluster EST : UnigeneHs.251680 [ NCBI ]
CGAP (NCI)Hs.251680
Alternative Splicing GalleryENSG00000203782
Gene ExpressionLOR [ NCBI-GEO ]   LOR [ EBI - ARRAY_EXPRESS ]   LOR [ SEEK ]   LOR [ MEM ]
Gene Expression Viewer (FireBrowse)LOR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4014
GTEX Portal (Tissue expression)LOR
Human Protein AtlasENSG00000203782-LOR [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP23490   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP23490  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP23490
Splice isoforms : SwissVarP23490
PhosPhoSitePlusP23490
Domains : Interpro (EBI)Loricrin   
Domain families : Pfam (Sanger)Loricrin (PF15847)   
Domain families : Pfam (NCBI)pfam15847   
Conserved Domain (NCBI)LOR
DMDM Disease mutations4014
Blocks (Seattle)LOR
SuperfamilyP23490
Human Protein Atlas [tissue]ENSG00000203782-LOR [tissue]
Peptide AtlasP23490
HPRD01070
IPIIPI00384560   IPI00011673   IPI00979540   
Protein Interaction databases
DIP (DOE-UCLA)P23490
IntAct (EBI)P23490
FunCoupENSG00000203782
BioGRIDLOR
STRING (EMBL)LOR
ZODIACLOR
Ontologies - Pathways
QuickGOP23490
Ontology : AmiGOcornified envelope  cornified envelope  structural molecule activity  structural constituent of cytoskeleton  protein binding  nucleoplasm  cytoplasm  cytosol  cytoskeleton organization  peptide cross-linking  keratinocyte differentiation  structural constituent of epidermis  protein binding, bridging  cornification  
Ontology : EGO-EBIcornified envelope  cornified envelope  structural molecule activity  structural constituent of cytoskeleton  protein binding  nucleoplasm  cytoplasm  cytosol  cytoskeleton organization  peptide cross-linking  keratinocyte differentiation  structural constituent of epidermis  protein binding, bridging  cornification  
NDEx NetworkLOR
Atlas of Cancer Signalling NetworkLOR
Wikipedia pathwaysLOR
Orthology - Evolution
OrthoDB4014
GeneTree (enSembl)ENSG00000203782
Phylogenetic Trees/Animal Genes : TreeFamLOR
HOVERGENP23490
HOGENOMP23490
Homologs : HomoloGeneLOR
Homology/Alignments : Family Browser (UCSC)LOR
Gene fusions - Rearrangements
Fusion : QuiverLOR
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLOR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LOR
dbVarLOR
ClinVarLOR
1000_GenomesLOR 
Exome Variant ServerLOR
ExAC (Exome Aggregation Consortium)ENSG00000203782
GNOMAD BrowserENSG00000203782
Genetic variants : HAPMAP4014
Genomic Variants (DGV)LOR [DGVbeta]
DECIPHERLOR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLOR 
Mutations
ICGC Data PortalLOR 
TCGA Data PortalLOR 
Broad Tumor PortalLOR
OASIS PortalLOR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLOR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLOR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LOR
DgiDB (Drug Gene Interaction Database)LOR
DoCM (Curated mutations)LOR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LOR (select a term)
intoGenLOR
Cancer3DLOR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM152445    604117   
Orphanet8631    11421   
DisGeNETLOR
MedgenLOR
Genetic Testing Registry LOR
NextProtP23490 [Medical]
TSGene4014
GENETestsLOR
Target ValidationLOR
Huge Navigator LOR [HugePedia]
snp3D : Map Gene to Disease4014
BioCentury BCIQLOR
ClinGenLOR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4014
Chemical/Pharm GKB GenePA30426
Clinical trialLOR
Miscellaneous
canSAR (ICR)LOR (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLOR
EVEXLOR
GoPubMedLOR
iHOPLOR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:34:05 CEST 2018

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