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LOXL1 (lysyl oxidase like 1)

Identity

Alias_nameslysyl oxidase-like 1
Alias_symbol (synonym)LOXL
LOL
Other alias
HGNC (Hugo) LOXL1
LocusID (NCBI) 4016
Atlas_Id 47157
Location 15q24.1  [Link to chromosome band 15q24]
Location_base_pair Starts at 73926458 and ends at 73952141 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LOXL1 (15q24.1) / KARS (16q23.1)LOXL1 (15q24.1) / LOXL1 (15q24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LOXL1   6665
Cards
Entrez_Gene (NCBI)LOXL1  4016  lysyl oxidase like 1
AliasesLOL; LOXL
GeneCards (Weizmann)LOXL1
Ensembl hg19 (Hinxton)ENSG00000129038 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129038 [Gene_View]  chr15:73926458-73952141 [Contig_View]  LOXL1 [Vega]
ICGC DataPortalENSG00000129038
TCGA cBioPortalLOXL1
AceView (NCBI)LOXL1
Genatlas (Paris)LOXL1
WikiGenes4016
SOURCE (Princeton)LOXL1
Genetics Home Reference (NIH)LOXL1
Genomic and cartography
GoldenPath hg38 (UCSC)LOXL1  -     chr15:73926458-73952141 +  15q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LOXL1  -     15q24.1   [Description]    (hg19-Feb_2009)
EnsemblLOXL1 - 15q24.1 [CytoView hg19]  LOXL1 - 15q24.1 [CytoView hg38]
Mapping of homologs : NCBILOXL1 [Mapview hg19]  LOXL1 [Mapview hg38]
OMIM153456   177650   
Gene and transcription
Genbank (Entrez)AI565419 AK303982 AK314222 AL529650 BC015090
RefSeq transcript (Entrez)NM_005576
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LOXL1
Cluster EST : UnigeneHs.65436 [ NCBI ]
CGAP (NCI)Hs.65436
Alternative Splicing GalleryENSG00000129038
Gene ExpressionLOXL1 [ NCBI-GEO ]   LOXL1 [ EBI - ARRAY_EXPRESS ]   LOXL1 [ SEEK ]   LOXL1 [ MEM ]
Gene Expression Viewer (FireBrowse)LOXL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4016
GTEX Portal (Tissue expression)LOXL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ08397   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ08397  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ08397
Splice isoforms : SwissVarQ08397
Catalytic activity : Enzyme1.4.3.- [ Enzyme-Expasy ]   1.4.3.-1.4.3.- [ IntEnz-EBI ]   1.4.3.- [ BRENDA ]   1.4.3.- [ KEGG ]   
PhosPhoSitePlusQ08397
Domaine pattern : Prosite (Expaxy)LYSYL_OXIDASE (PS00926)   
Domains : Interpro (EBI)Lysyl_oxidase    Lysyl_oxidase_CS   
Domain families : Pfam (Sanger)Lysyl_oxidase (PF01186)   
Domain families : Pfam (NCBI)pfam01186   
Conserved Domain (NCBI)LOXL1
DMDM Disease mutations4016
Blocks (Seattle)LOXL1
SuperfamilyQ08397
Human Protein AtlasENSG00000129038
Peptide AtlasQ08397
HPRD08861
IPIIPI00001597   IPI01012092   
Protein Interaction databases
DIP (DOE-UCLA)Q08397
IntAct (EBI)Q08397
FunCoupENSG00000129038
BioGRIDLOXL1
STRING (EMBL)LOXL1
ZODIACLOXL1
Ontologies - Pathways
QuickGOQ08397
Ontology : AmiGOacrosomal vesicle  copper ion binding  extracellular region  basement membrane  extracellular space  oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor  protein deamination  extracellular matrix organization  extracellular matrix  response to lipopolysaccharide  aorta development  oxidation-reduction process  
Ontology : EGO-EBIacrosomal vesicle  copper ion binding  extracellular region  basement membrane  extracellular space  oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor  protein deamination  extracellular matrix organization  extracellular matrix  response to lipopolysaccharide  aorta development  oxidation-reduction process  
NDEx NetworkLOXL1
Atlas of Cancer Signalling NetworkLOXL1
Wikipedia pathwaysLOXL1
Orthology - Evolution
OrthoDB4016
GeneTree (enSembl)ENSG00000129038
Phylogenetic Trees/Animal Genes : TreeFamLOXL1
HOVERGENQ08397
HOGENOMQ08397
Homologs : HomoloGeneLOXL1
Homology/Alignments : Family Browser (UCSC)LOXL1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLOXL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LOXL1
dbVarLOXL1
ClinVarLOXL1
1000_GenomesLOXL1 
Exome Variant ServerLOXL1
ExAC (Exome Aggregation Consortium)LOXL1 (select the gene name)
Genetic variants : HAPMAP4016
Genomic Variants (DGV)LOXL1 [DGVbeta]
DECIPHERLOXL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLOXL1 
Mutations
ICGC Data PortalLOXL1 
TCGA Data PortalLOXL1 
Broad Tumor PortalLOXL1
OASIS PortalLOXL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLOXL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLOXL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LOXL1
DgiDB (Drug Gene Interaction Database)LOXL1
DoCM (Curated mutations)LOXL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LOXL1 (select a term)
intoGenLOXL1
Cancer3DLOXL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM153456    177650   
Orphanet
MedgenLOXL1
Genetic Testing Registry LOXL1
NextProtQ08397 [Medical]
TSGene4016
GENETestsLOXL1
Target ValidationLOXL1
Huge Navigator LOXL1 [HugePedia]
snp3D : Map Gene to Disease4016
BioCentury BCIQLOXL1
ClinGenLOXL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4016
Chemical/Pharm GKB GenePA30428
Clinical trialLOXL1
Miscellaneous
canSAR (ICR)LOXL1 (select the gene name)
Probes
Litterature
PubMed126 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLOXL1
EVEXLOXL1
GoPubMedLOXL1
iHOPLOXL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:41:26 CEST 2017

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