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LPCAT2 (lysophosphatidylcholine acyltransferase 2)

Identity

Alias_namesAYTL1
acyltransferase like 1
Alias_symbol (synonym)FLJ20481
AGPAT11
LysoPAFAT
Other alias
HGNC (Hugo) LPCAT2
LocusID (NCBI) 54947
Atlas_Id 55528
Location 16q12.2  [Link to chromosome band 16q12]
Location_base_pair Starts at 55509001 and ends at 55586670 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATP6V1D (14q23.3) / LPCAT2 (16q12.2)LPCAT2 (16q12.2) / CACTIN (19p13.3)LPCAT2 (16q12.2) / LPCAT2 (16q12.2)
LPCAT2 (16q12.2) / TXNDC5 (6p24.3)ZNF77 (19p13.3) / LPCAT2 (16q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LPCAT2   26032
Cards
Entrez_Gene (NCBI)LPCAT2  54947  lysophosphatidylcholine acyltransferase 2
AliasesAGPAT11; AYTL1; LysoPAFAT
GeneCards (Weizmann)LPCAT2
Ensembl hg19 (Hinxton)ENSG00000087253 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000087253 [Gene_View]  chr16:55509001-55586670 [Contig_View]  LPCAT2 [Vega]
ICGC DataPortalENSG00000087253
TCGA cBioPortalLPCAT2
AceView (NCBI)LPCAT2
Genatlas (Paris)LPCAT2
WikiGenes54947
SOURCE (Princeton)LPCAT2
Genetics Home Reference (NIH)LPCAT2
Genomic and cartography
GoldenPath hg38 (UCSC)LPCAT2  -     chr16:55509001-55586670 +  16q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LPCAT2  -     16q12.2   [Description]    (hg19-Feb_2009)
EnsemblLPCAT2 - 16q12.2 [CytoView hg19]  LPCAT2 - 16q12.2 [CytoView hg38]
Mapping of homologs : NCBILPCAT2 [Mapview hg19]  LPCAT2 [Mapview hg38]
OMIM612040   
Gene and transcription
Genbank (Entrez)AB244718 AI915099 AK000488 AK023271 AK126523
RefSeq transcript (Entrez)NM_017839
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LPCAT2
Cluster EST : UnigeneHs.460857 [ NCBI ]
CGAP (NCI)Hs.460857
Alternative Splicing GalleryENSG00000087253
Gene ExpressionLPCAT2 [ NCBI-GEO ]   LPCAT2 [ EBI - ARRAY_EXPRESS ]   LPCAT2 [ SEEK ]   LPCAT2 [ MEM ]
Gene Expression Viewer (FireBrowse)LPCAT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54947
GTEX Portal (Tissue expression)LPCAT2
Human Protein AtlasENSG00000087253-LPCAT2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7L5N7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7L5N7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7L5N7
Splice isoforms : SwissVarQ7L5N7
Catalytic activity : Enzyme2.3.1.23 [ Enzyme-Expasy ]   2.3.1.232.3.1.23 [ IntEnz-EBI ]   2.3.1.23 [ BRENDA ]   2.3.1.23 [ KEGG ]   
PhosPhoSitePlusQ7L5N7
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    Plipid/glycerol_acylTrfase   
Domain families : Pfam (Sanger)Acyltransferase (PF01553)    EF-hand_7 (PF13499)   
Domain families : Pfam (NCBI)pfam01553    pfam13499   
Domain families : Smart (EMBL)EFh (SM00054)  PlsC (SM00563)  
Conserved Domain (NCBI)LPCAT2
DMDM Disease mutations54947
Blocks (Seattle)LPCAT2
SuperfamilyQ7L5N7
Human Protein Atlas [tissue]ENSG00000087253-LPCAT2 [tissue]
Peptide AtlasQ7L5N7
HPRD07913
IPIIPI00016418   IPI00643943   
Protein Interaction databases
DIP (DOE-UCLA)Q7L5N7
IntAct (EBI)Q7L5N7
FunCoupENSG00000087253
BioGRIDLPCAT2
STRING (EMBL)LPCAT2
ZODIACLPCAT2
Ontologies - Pathways
QuickGOQ7L5N7
Ontology : AmiGOGolgi membrane  1-acylglycerol-3-phosphate O-acyltransferase activity  calcium ion binding  endoplasmic reticulum  endoplasmic reticulum  endoplasmic reticulum membrane  Golgi stack  lipid particle  platelet activating factor biosynthetic process  integral component of membrane  phosphatidylcholine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  2-acylglycerol-3-phosphate O-acyltransferase activity  1-acylglycerophosphocholine O-acyltransferase activity  1-acylglycerophosphocholine O-acyltransferase activity  1-alkylglycerophosphocholine O-acetyltransferase activity  membrane organization  
Ontology : EGO-EBIGolgi membrane  1-acylglycerol-3-phosphate O-acyltransferase activity  calcium ion binding  endoplasmic reticulum  endoplasmic reticulum  endoplasmic reticulum membrane  Golgi stack  lipid particle  platelet activating factor biosynthetic process  integral component of membrane  phosphatidylcholine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  2-acylglycerol-3-phosphate O-acyltransferase activity  1-acylglycerophosphocholine O-acyltransferase activity  1-acylglycerophosphocholine O-acyltransferase activity  1-alkylglycerophosphocholine O-acetyltransferase activity  membrane organization  
Pathways : KEGGGlycerophospholipid metabolism    Ether lipid metabolism   
NDEx NetworkLPCAT2
Atlas of Cancer Signalling NetworkLPCAT2
Wikipedia pathwaysLPCAT2
Orthology - Evolution
OrthoDB54947
GeneTree (enSembl)ENSG00000087253
Phylogenetic Trees/Animal Genes : TreeFamLPCAT2
HOVERGENQ7L5N7
HOGENOMQ7L5N7
Homologs : HomoloGeneLPCAT2
Homology/Alignments : Family Browser (UCSC)LPCAT2
Gene fusions - Rearrangements
Tumor Fusion PortalLPCAT2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLPCAT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LPCAT2
dbVarLPCAT2
ClinVarLPCAT2
1000_GenomesLPCAT2 
Exome Variant ServerLPCAT2
ExAC (Exome Aggregation Consortium)ENSG00000087253
GNOMAD BrowserENSG00000087253
Genetic variants : HAPMAP54947
Genomic Variants (DGV)LPCAT2 [DGVbeta]
DECIPHERLPCAT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLPCAT2 
Mutations
ICGC Data PortalLPCAT2 
TCGA Data PortalLPCAT2 
Broad Tumor PortalLPCAT2
OASIS PortalLPCAT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLPCAT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLPCAT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LPCAT2
DgiDB (Drug Gene Interaction Database)LPCAT2
DoCM (Curated mutations)LPCAT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LPCAT2 (select a term)
intoGenLPCAT2
Cancer3DLPCAT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612040   
Orphanet
DisGeNETLPCAT2
MedgenLPCAT2
Genetic Testing Registry LPCAT2
NextProtQ7L5N7 [Medical]
TSGene54947
GENETestsLPCAT2
Target ValidationLPCAT2
Huge Navigator LPCAT2 [HugePedia]
snp3D : Map Gene to Disease54947
BioCentury BCIQLPCAT2
ClinGenLPCAT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54947
Chemical/Pharm GKB GenePA162394265
Clinical trialLPCAT2
Miscellaneous
canSAR (ICR)LPCAT2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLPCAT2
EVEXLPCAT2
GoPubMedLPCAT2
iHOPLPCAT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:20:50 CET 2017

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