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LPCAT4 (lysophosphatidylcholine acyltransferase 4)

Identity

Alias_namesAYTL3
AGPAT7
acyltransferase like 3
1-acylglycerol-3-phosphate O-acyltransferase 7 (lysophosphatidic acid acyltransferase, eta)
Alias_symbol (synonym)FLJ10257
LPAAT-eta
LPEAT2
Other alias
HGNC (Hugo) LPCAT4
LocusID (NCBI) 254531
Atlas_Id 53625
Location 15q14  [Link to chromosome band 15q14]
Location_base_pair Starts at 34358888 and ends at 34367194 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LPCAT4   30059
Cards
Entrez_Gene (NCBI)LPCAT4  254531  lysophosphatidylcholine acyltransferase 4
AliasesAGPAT7; AYTL3; LPAAT-eta; LPEAT2
GeneCards (Weizmann)LPCAT4
Ensembl hg19 (Hinxton)ENSG00000176454 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176454 [Gene_View]  chr15:34358888-34367194 [Contig_View]  LPCAT4 [Vega]
ICGC DataPortalENSG00000176454
TCGA cBioPortalLPCAT4
AceView (NCBI)LPCAT4
Genatlas (Paris)LPCAT4
WikiGenes254531
SOURCE (Princeton)LPCAT4
Genetics Home Reference (NIH)LPCAT4
Genomic and cartography
GoldenPath hg38 (UCSC)LPCAT4  -     chr15:34358888-34367194 -  15q14   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LPCAT4  -     15q14   [Description]    (hg19-Feb_2009)
EnsemblLPCAT4 - 15q14 [CytoView hg19]  LPCAT4 - 15q14 [CytoView hg38]
Mapping of homologs : NCBILPCAT4 [Mapview hg19]  LPCAT4 [Mapview hg38]
OMIM612039   
Gene and transcription
Genbank (Entrez)AF007155 AF529233 AF542964 AK001119 AK290273
RefSeq transcript (Entrez)NM_153613
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LPCAT4
Cluster EST : UnigeneHs.352614 [ NCBI ]
CGAP (NCI)Hs.352614
Alternative Splicing GalleryENSG00000176454
Gene ExpressionLPCAT4 [ NCBI-GEO ]   LPCAT4 [ EBI - ARRAY_EXPRESS ]   LPCAT4 [ SEEK ]   LPCAT4 [ MEM ]
Gene Expression Viewer (FireBrowse)LPCAT4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)254531
GTEX Portal (Tissue expression)LPCAT4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ643R3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ643R3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ643R3
Splice isoforms : SwissVarQ643R3
Catalytic activity : Enzyme2.3.1.23 [ Enzyme-Expasy ]   2.3.1.232.3.1.23 [ IntEnz-EBI ]   2.3.1.23 [ BRENDA ]   2.3.1.23 [ KEGG ]   
PhosPhoSitePlusQ643R3
Domains : Interpro (EBI)EF-hand-dom_pair    Plipid/glycerol_acylTrfase   
Domain families : Pfam (Sanger)Acyltransferase (PF01553)   
Domain families : Pfam (NCBI)pfam01553   
Domain families : Smart (EMBL)PlsC (SM00563)  
Conserved Domain (NCBI)LPCAT4
DMDM Disease mutations254531
Blocks (Seattle)LPCAT4
SuperfamilyQ643R3
Human Protein AtlasENSG00000176454
Peptide AtlasQ643R3
HPRD08315
IPIIPI00385128   IPI00783192   
Protein Interaction databases
DIP (DOE-UCLA)Q643R3
IntAct (EBI)Q643R3
FunCoupENSG00000176454
BioGRIDLPCAT4
STRING (EMBL)LPCAT4
ZODIACLPCAT4
Ontologies - Pathways
QuickGOQ643R3
Ontology : AmiGO1-acylglycerol-3-phosphate O-acyltransferase activity  endoplasmic reticulum  endoplasmic reticulum membrane  phospholipid metabolic process  phospholipid metabolic process  phosphatidic acid biosynthetic process  membrane  integral component of membrane  triglyceride biosynthetic process  phosphatidylglycerol acyl-chain remodeling  phosphatidylserine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  2-acylglycerol-3-phosphate O-acyltransferase activity  1-alkenylglycerophosphoethanolamine O-acyltransferase activity  1-acylglycerophosphocholine O-acyltransferase activity  1-alkylglycerophosphocholine O-acetyltransferase activity  lysophospholipid acyltransferase activity  lysophospholipid acyltransferase activity  
Ontology : EGO-EBI1-acylglycerol-3-phosphate O-acyltransferase activity  endoplasmic reticulum  endoplasmic reticulum membrane  phospholipid metabolic process  phospholipid metabolic process  phosphatidic acid biosynthetic process  membrane  integral component of membrane  triglyceride biosynthetic process  phosphatidylglycerol acyl-chain remodeling  phosphatidylserine acyl-chain remodeling  phosphatidylcholine acyl-chain remodeling  phosphatidylethanolamine acyl-chain remodeling  2-acylglycerol-3-phosphate O-acyltransferase activity  1-alkenylglycerophosphoethanolamine O-acyltransferase activity  1-acylglycerophosphocholine O-acyltransferase activity  1-alkylglycerophosphocholine O-acetyltransferase activity  lysophospholipid acyltransferase activity  lysophospholipid acyltransferase activity  
Pathways : KEGGGlycerophospholipid metabolism    Ether lipid metabolism   
NDEx NetworkLPCAT4
Atlas of Cancer Signalling NetworkLPCAT4
Wikipedia pathwaysLPCAT4
Orthology - Evolution
OrthoDB254531
GeneTree (enSembl)ENSG00000176454
Phylogenetic Trees/Animal Genes : TreeFamLPCAT4
HOVERGENQ643R3
HOGENOMQ643R3
Homologs : HomoloGeneLPCAT4
Homology/Alignments : Family Browser (UCSC)LPCAT4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLPCAT4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LPCAT4
dbVarLPCAT4
ClinVarLPCAT4
1000_GenomesLPCAT4 
Exome Variant ServerLPCAT4
ExAC (Exome Aggregation Consortium)LPCAT4 (select the gene name)
Genetic variants : HAPMAP254531
Genomic Variants (DGV)LPCAT4 [DGVbeta]
DECIPHERLPCAT4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLPCAT4 
Mutations
ICGC Data PortalLPCAT4 
TCGA Data PortalLPCAT4 
Broad Tumor PortalLPCAT4
OASIS PortalLPCAT4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLPCAT4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLPCAT4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LPCAT4
DgiDB (Drug Gene Interaction Database)LPCAT4
DoCM (Curated mutations)LPCAT4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LPCAT4 (select a term)
intoGenLPCAT4
Cancer3DLPCAT4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612039   
Orphanet
MedgenLPCAT4
Genetic Testing Registry LPCAT4
NextProtQ643R3 [Medical]
TSGene254531
GENETestsLPCAT4
Target ValidationLPCAT4
Huge Navigator LPCAT4 [HugePedia]
snp3D : Map Gene to Disease254531
BioCentury BCIQLPCAT4
ClinGenLPCAT4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD254531
Chemical/Pharm GKB GenePA162394297
Clinical trialLPCAT4
Miscellaneous
canSAR (ICR)LPCAT4 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLPCAT4
EVEXLPCAT4
GoPubMedLPCAT4
iHOPLPCAT4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:16:24 CEST 2017

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