Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LPIN2 (lipin 2)

Identity

Alias_symbol (synonym)KIAA0249
Other alias-
HGNC (Hugo) LPIN2
LocusID (NCBI) 9663
Atlas_Id 56317
Location 18p11.31  [Link to chromosome band 18p11]
Location_base_pair Starts at 2916994 and ends at 3011947 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LPIN2 (18p11.31) / MYOM1 (18p11.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LPIN2   14450
LRG (Locus Reference Genomic)LRG_174
Cards
Entrez_Gene (NCBI)LPIN2  9663  lipin 2
Aliases
GeneCards (Weizmann)LPIN2
Ensembl hg19 (Hinxton)ENSG00000101577 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101577 [Gene_View]  chr18:2916994-3011947 [Contig_View]  LPIN2 [Vega]
ICGC DataPortalENSG00000101577
TCGA cBioPortalLPIN2
AceView (NCBI)LPIN2
Genatlas (Paris)LPIN2
WikiGenes9663
SOURCE (Princeton)LPIN2
Genetics Home Reference (NIH)LPIN2
Genomic and cartography
GoldenPath hg38 (UCSC)LPIN2  -     chr18:2916994-3011947 -  18p11.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LPIN2  -     18p11.31   [Description]    (hg19-Feb_2009)
EnsemblLPIN2 - 18p11.31 [CytoView hg19]  LPIN2 - 18p11.31 [CytoView hg38]
Mapping of homologs : NCBILPIN2 [Mapview hg19]  LPIN2 [Mapview hg38]
OMIM605519   609628   
Gene and transcription
Genbank (Entrez)BC152448 BC160018 BQ014306 D87436
RefSeq transcript (Entrez)NM_014646
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LPIN2
Cluster EST : UnigeneHs.132342 [ NCBI ]
CGAP (NCI)Hs.132342
Alternative Splicing GalleryENSG00000101577
Gene ExpressionLPIN2 [ NCBI-GEO ]   LPIN2 [ EBI - ARRAY_EXPRESS ]   LPIN2 [ SEEK ]   LPIN2 [ MEM ]
Gene Expression Viewer (FireBrowse)LPIN2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9663
GTEX Portal (Tissue expression)LPIN2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92539   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92539  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92539
Splice isoforms : SwissVarQ92539
Catalytic activity : Enzyme3.1.3.4 [ Enzyme-Expasy ]   3.1.3.43.1.3.4 [ IntEnz-EBI ]   3.1.3.4 [ BRENDA ]   3.1.3.4 [ KEGG ]   
PhosPhoSitePlusQ92539
Domains : Interpro (EBI)HAD-like_dom    Lipin_mid    Lipin_N    LNS2    LNS2/PITP    LPIN2   
Domain families : Pfam (Sanger)Lipin_mid (PF16876)    Lipin_N (PF04571)    LNS2 (PF08235)   
Domain families : Pfam (NCBI)pfam16876    pfam04571    pfam08235   
Domain families : Smart (EMBL)LNS2 (SM00775)  
Conserved Domain (NCBI)LPIN2
DMDM Disease mutations9663
Blocks (Seattle)LPIN2
SuperfamilyQ92539
Human Protein AtlasENSG00000101577
Peptide AtlasQ92539
HPRD16114
IPIIPI00021956   IPI00852902   IPI00641432   
Protein Interaction databases
DIP (DOE-UCLA)Q92539
IntAct (EBI)Q92539
FunCoupENSG00000101577
BioGRIDLPIN2
STRING (EMBL)LPIN2
ZODIACLPIN2
Ontologies - Pathways
QuickGOQ92539
Ontology : AmiGOtranscription coactivator activity  transcription coactivator activity  nucleus  endoplasmic reticulum membrane  endoplasmic reticulum membrane  cytosol  transcription, DNA-templated  lipid metabolic process  phosphatidylethanolamine biosynthetic process  phosphatidylcholine biosynthetic process  phosphatidate phosphatase activity  phosphatidate phosphatase activity  phosphatidate phosphatase activity  fatty acid catabolic process  dephosphorylation  triglyceride biosynthetic process  triglyceride biosynthetic process  positive regulation of transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  
Ontology : EGO-EBItranscription coactivator activity  transcription coactivator activity  nucleus  endoplasmic reticulum membrane  endoplasmic reticulum membrane  cytosol  transcription, DNA-templated  lipid metabolic process  phosphatidylethanolamine biosynthetic process  phosphatidylcholine biosynthetic process  phosphatidate phosphatase activity  phosphatidate phosphatase activity  phosphatidate phosphatase activity  fatty acid catabolic process  dephosphorylation  triglyceride biosynthetic process  triglyceride biosynthetic process  positive regulation of transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  
Pathways : KEGGGlycerolipid metabolism    Glycerophospholipid metabolism   
NDEx NetworkLPIN2
Atlas of Cancer Signalling NetworkLPIN2
Wikipedia pathwaysLPIN2
Orthology - Evolution
OrthoDB9663
GeneTree (enSembl)ENSG00000101577
Phylogenetic Trees/Animal Genes : TreeFamLPIN2
HOVERGENQ92539
HOGENOMQ92539
Homologs : HomoloGeneLPIN2
Homology/Alignments : Family Browser (UCSC)LPIN2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLPIN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LPIN2
dbVarLPIN2
ClinVarLPIN2
1000_GenomesLPIN2 
Exome Variant ServerLPIN2
ExAC (Exome Aggregation Consortium)LPIN2 (select the gene name)
Genetic variants : HAPMAP9663
Genomic Variants (DGV)LPIN2 [DGVbeta]
DECIPHERLPIN2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLPIN2 
Mutations
ICGC Data PortalLPIN2 
TCGA Data PortalLPIN2 
Broad Tumor PortalLPIN2
OASIS PortalLPIN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLPIN2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLPIN2
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch LPIN2
DgiDB (Drug Gene Interaction Database)LPIN2
DoCM (Curated mutations)LPIN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LPIN2 (select a term)
intoGenLPIN2
Cancer3DLPIN2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605519    609628   
Orphanet11109   
MedgenLPIN2
Genetic Testing Registry LPIN2
NextProtQ92539 [Medical]
TSGene9663
GENETestsLPIN2
Huge Navigator LPIN2 [HugePedia]
snp3D : Map Gene to Disease9663
BioCentury BCIQLPIN2
ClinGenLPIN2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9663
Chemical/Pharm GKB GenePA30437
Clinical trialLPIN2
Miscellaneous
canSAR (ICR)LPIN2 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLPIN2
EVEXLPIN2
GoPubMedLPIN2
iHOPLPIN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:23:25 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.