LPO (lactoperoxidase)

2014-11-01  

Identity

HGNC
LPO
LOCATION
17q22
LOCUSID
4025
ALIAS
SPO
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4025
MIM: 150205
HGNC: 6678
Ensembl: ENSG00000167419

Variants:

dbSNP: 4025
ClinVar: 4025
TCGA: ENSG00000167419
COSMIC: LPO

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167419ENST00000262290P22079
ENSG00000167419ENST00000389576H0Y3I2
ENSG00000167419ENST00000421678P22079
ENSG00000167419ENST00000543544F5H386
ENSG00000167419ENST00000580890J3KT11
ENSG00000167419ENST00000581008J3QSD8
ENSG00000167419ENST00000582328P22079

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Salivary secretionKEGGko04970
Salivary secretionKEGGhsa04970

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
126263412003Lactoperoxidase and human airway host defense.69
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
158948002005Thiocyanate modulates the catalytic activity of mammalian peroxidases.21
195059172009Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.21
194235402009Common variation in genes related to innate immunity and risk of adult glioma.19
204069642010Risk of meningioma and common variation in genes related to innate immunity.12
249285132014Uric acid and thiocyanate as competing substrates of lactoperoxidase.9
249741092014The assessment of sIgA, histatin-5, and lactoperoxidase levels in saliva of adolescents with dental caries.8
190591952009Molecular heterogeneity and alternative splicing of human lactoperoxidase.7
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.5

Citation

Dessen P

LPO (lactoperoxidase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68565/lpo