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LPO (lactoperoxidase)

Identity

Alias_symbol (synonym)SPO
Other alias
HGNC (Hugo) LPO
LocusID (NCBI) 4025
Atlas_Id 68565
Location 17q22  [Link to chromosome band 17q22]
Location_base_pair Starts at 56315787 and ends at 56345879 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MICAL2 (11p15.3) / LPO (17q22)SRP68 (17q25.1) / LPO (17q22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LPO   6678
Cards
Entrez_Gene (NCBI)LPO  4025  lactoperoxidase
AliasesSPO
GeneCards (Weizmann)LPO
Ensembl hg19 (Hinxton)ENSG00000167419 [Gene_View]  chr17:56315787-56345879 [Contig_View]  LPO [Vega]
Ensembl hg38 (Hinxton)ENSG00000167419 [Gene_View]  chr17:56315787-56345879 [Contig_View]  LPO [Vega]
ICGC DataPortalENSG00000167419
TCGA cBioPortalLPO
AceView (NCBI)LPO
Genatlas (Paris)LPO
WikiGenes4025
SOURCE (Princeton)LPO
Genetics Home Reference (NIH)LPO
Genomic and cartography
GoldenPath hg19 (UCSC)LPO  -     chr17:56315787-56345879 +  17q22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LPO  -     17q22   [Description]    (hg38-Dec_2013)
EnsemblLPO - 17q22 [CytoView hg19]  LPO - 17q22 [CytoView hg38]
Mapping of homologs : NCBILPO [Mapview hg19]  LPO [Mapview hg38]
OMIM150205   
Gene and transcription
Genbank (Entrez)AF027971 AK131496 AK300653 AK303903 AK308378
RefSeq transcript (Entrez)NM_001160102 NM_006151
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)LPO
Cluster EST : UnigeneHs.234742 [ NCBI ]
CGAP (NCI)Hs.234742
Alternative Splicing GalleryENSG00000167419
Gene ExpressionLPO [ NCBI-GEO ]   LPO [ EBI - ARRAY_EXPRESS ]   LPO [ SEEK ]   LPO [ MEM ]
Gene Expression Viewer (FireBrowse)LPO [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4025
GTEX Portal (Tissue expression)LPO
Protein : pattern, domain, 3D structure
UniProt/SwissProtP22079   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP22079  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP22079
Splice isoforms : SwissVarP22079
Catalytic activity : Enzyme1.11.1.7 [ Enzyme-Expasy ]   1.11.1.71.11.1.7 [ IntEnz-EBI ]   1.11.1.7 [ BRENDA ]   1.11.1.7 [ KEGG ]   
PhosPhoSitePlusP22079
Domaine pattern : Prosite (Expaxy)PEROXIDASE_3 (PS50292)   
Domains : Interpro (EBI)Haem_peroxidase    Haem_peroxidase_animal    LPO   
Domain families : Pfam (Sanger)An_peroxidase (PF03098)   
Domain families : Pfam (NCBI)pfam03098   
Conserved Domain (NCBI)LPO
DMDM Disease mutations4025
Blocks (Seattle)LPO
SuperfamilyP22079
Human Protein AtlasENSG00000167419
Peptide AtlasP22079
HPRD11825
IPIIPI00025023   IPI01009191   IPI01013019   IPI00783810   
Protein Interaction databases
DIP (DOE-UCLA)P22079
IntAct (EBI)P22079
FunCoupENSG00000167419
BioGRIDLPO
STRING (EMBL)LPO
ZODIACLPO
Ontologies - Pathways
QuickGOP22079
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of bitter taste  extracellular space  cytoplasm  response to oxidative stress  basolateral plasma membrane  thiocyanate metabolic process  thiocyanate metabolic process  heme binding  thiocyanate peroxidase activity  defense response to bacterium  hydrogen peroxide catabolic process  metal ion binding  oxidation-reduction process  extracellular exosome  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of bitter taste  extracellular space  cytoplasm  response to oxidative stress  basolateral plasma membrane  thiocyanate metabolic process  thiocyanate metabolic process  heme binding  thiocyanate peroxidase activity  defense response to bacterium  hydrogen peroxide catabolic process  metal ion binding  oxidation-reduction process  extracellular exosome  
Pathways : KEGGSalivary secretion   
NDEx NetworkLPO
Atlas of Cancer Signalling NetworkLPO
Wikipedia pathwaysLPO
Orthology - Evolution
OrthoDB4025
GeneTree (enSembl)ENSG00000167419
Phylogenetic Trees/Animal Genes : TreeFamLPO
HOVERGENP22079
HOGENOMP22079
Homologs : HomoloGeneLPO
Homology/Alignments : Family Browser (UCSC)LPO
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLPO [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LPO
dbVarLPO
ClinVarLPO
1000_GenomesLPO 
Exome Variant ServerLPO
ExAC (Exome Aggregation Consortium)LPO (select the gene name)
Genetic variants : HAPMAP4025
Genomic Variants (DGV)LPO [DGVbeta]
DECIPHER (Syndromes)17:56315787-56345879  ENSG00000167419
CONAN: Copy Number AnalysisLPO 
Mutations
ICGC Data PortalLPO 
TCGA Data PortalLPO 
Broad Tumor PortalLPO
OASIS PortalLPO [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLPO  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLPO
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LPO
DgiDB (Drug Gene Interaction Database)LPO
DoCM (Curated mutations)LPO (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LPO (select a term)
intoGenLPO
Cancer3DLPO(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM150205   
Orphanet
MedgenLPO
Genetic Testing Registry LPO
NextProtP22079 [Medical]
TSGene4025
GENETestsLPO
Huge Navigator LPO [HugePedia]
snp3D : Map Gene to Disease4025
BioCentury BCIQLPO
ClinGenLPO
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4025
Chemical/Pharm GKB GenePA30439
Clinical trialLPO
Miscellaneous
canSAR (ICR)LPO (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLPO
EVEXLPO
GoPubMedLPO
iHOPLPO
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:26:54 CET 2017

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