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LRFN2 (leucine rich repeat and fibronectin type III domain containing 2)

Identity

Alias_namesKIAA1246
SALM1
KIAA1246
Alias_symbol (synonym)FIGLER2
Other alias
HGNC (Hugo) LRFN2
LocusID (NCBI) 57497
Atlas_Id 68577
Location 6p21.2  [Link to chromosome band 6p21]
Location_base_pair Starts at 40391634 and ends at 40587464 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LRFN2 (6p21.2) / UTP15 (5q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRFN2   21226
Cards
Entrez_Gene (NCBI)LRFN2  57497  leucine rich repeat and fibronectin type III domain containing 2
AliasesFIGLER2; KIAA1246; SALM1
GeneCards (Weizmann)LRFN2
Ensembl hg19 (Hinxton)ENSG00000156564 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156564 [Gene_View]  chr6:40391634-40587464 [Contig_View]  LRFN2 [Vega]
ICGC DataPortalENSG00000156564
TCGA cBioPortalLRFN2
AceView (NCBI)LRFN2
Genatlas (Paris)LRFN2
WikiGenes57497
SOURCE (Princeton)LRFN2
Genetics Home Reference (NIH)LRFN2
Genomic and cartography
GoldenPath hg38 (UCSC)LRFN2  -     chr6:40391634-40587464 -  6p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRFN2  -     6p21.2   [Description]    (hg19-Feb_2009)
EnsemblLRFN2 - 6p21.2 [CytoView hg19]  LRFN2 - 6p21.2 [CytoView hg38]
Mapping of homologs : NCBILRFN2 [Mapview hg19]  LRFN2 [Mapview hg38]
OMIM612808   
Gene and transcription
Genbank (Entrez)AB033072 AK291474 BC142616 DA779371
RefSeq transcript (Entrez)NM_020737
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRFN2
Cluster EST : UnigeneHs.250015 [ NCBI ]
CGAP (NCI)Hs.250015
Alternative Splicing GalleryENSG00000156564
Gene ExpressionLRFN2 [ NCBI-GEO ]   LRFN2 [ EBI - ARRAY_EXPRESS ]   LRFN2 [ SEEK ]   LRFN2 [ MEM ]
Gene Expression Viewer (FireBrowse)LRFN2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57497
GTEX Portal (Tissue expression)LRFN2
Human Protein AtlasENSG00000156564-LRFN2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULH4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULH4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULH4
Splice isoforms : SwissVarQ9ULH4
PhosPhoSitePlusQ9ULH4
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    IG_LIKE (PS50835)    LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    FN3_dom    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp   
Domain families : Pfam (Sanger)fn3 (PF00041)    I-set (PF07679)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam00041    pfam07679    pfam13855   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  LRR_TYP (SM00369)  LRRCT (SM00082)  
Conserved Domain (NCBI)LRFN2
DMDM Disease mutations57497
Blocks (Seattle)LRFN2
SuperfamilyQ9ULH4
Human Protein Atlas [tissue]ENSG00000156564-LRFN2 [tissue]
Peptide AtlasQ9ULH4
HPRD17444
IPIIPI00008107   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULH4
IntAct (EBI)Q9ULH4
FunCoupENSG00000156564
BioGRIDLRFN2
STRING (EMBL)LRFN2
ZODIACLRFN2
Ontologies - Pathways
QuickGOQ9ULH4
Ontology : AmiGOproteinaceous extracellular matrix  extracellular space  plasma membrane  axonogenesis  cell surface  integral component of membrane  cell junction  postsynaptic membrane  
Ontology : EGO-EBIproteinaceous extracellular matrix  extracellular space  plasma membrane  axonogenesis  cell surface  integral component of membrane  cell junction  postsynaptic membrane  
NDEx NetworkLRFN2
Atlas of Cancer Signalling NetworkLRFN2
Wikipedia pathwaysLRFN2
Orthology - Evolution
OrthoDB57497
GeneTree (enSembl)ENSG00000156564
Phylogenetic Trees/Animal Genes : TreeFamLRFN2
HOVERGENQ9ULH4
HOGENOMQ9ULH4
Homologs : HomoloGeneLRFN2
Homology/Alignments : Family Browser (UCSC)LRFN2
Gene fusions - Rearrangements
Fusion : QuiverLRFN2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRFN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRFN2
dbVarLRFN2
ClinVarLRFN2
1000_GenomesLRFN2 
Exome Variant ServerLRFN2
ExAC (Exome Aggregation Consortium)ENSG00000156564
GNOMAD BrowserENSG00000156564
Genetic variants : HAPMAP57497
Genomic Variants (DGV)LRFN2 [DGVbeta]
DECIPHERLRFN2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRFN2 
Mutations
ICGC Data PortalLRFN2 
TCGA Data PortalLRFN2 
Broad Tumor PortalLRFN2
OASIS PortalLRFN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRFN2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRFN2
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LRFN2
DgiDB (Drug Gene Interaction Database)LRFN2
DoCM (Curated mutations)LRFN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRFN2 (select a term)
intoGenLRFN2
Cancer3DLRFN2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612808   
Orphanet
DisGeNETLRFN2
MedgenLRFN2
Genetic Testing Registry LRFN2
NextProtQ9ULH4 [Medical]
TSGene57497
GENETestsLRFN2
Target ValidationLRFN2
Huge Navigator LRFN2 [HugePedia]
snp3D : Map Gene to Disease57497
BioCentury BCIQLRFN2
ClinGenLRFN2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57497
Chemical/Pharm GKB GenePA134913285
Clinical trialLRFN2
Miscellaneous
canSAR (ICR)LRFN2 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRFN2
EVEXLRFN2
GoPubMedLRFN2
iHOPLRFN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Feb 23 18:38:32 CET 2018

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