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LRG1 (leucine-rich alpha-2-glycoprotein 1)

Identity

Alias_symbol (synonym)LRG
Other aliasHMFT1766
HGNC (Hugo) LRG1
LocusID (NCBI) 116844
Atlas_Id 52827
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 4537227 and ends at 4540036 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRG1   29480
Cards
Entrez_Gene (NCBI)LRG1  116844  leucine-rich alpha-2-glycoprotein 1
AliasesHMFT1766; LRG
GeneCards (Weizmann)LRG1
Ensembl hg19 (Hinxton)ENSG00000171236 [Gene_View]  chr19:4537227-4540036 [Contig_View]  LRG1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000171236 [Gene_View]  chr19:4537227-4540036 [Contig_View]  LRG1 [Vega]
ICGC DataPortalENSG00000171236
TCGA cBioPortalLRG1
AceView (NCBI)LRG1
Genatlas (Paris)LRG1
WikiGenes116844
SOURCE (Princeton)LRG1
Genetics Home Reference (NIH)LRG1
Genomic and cartography
GoldenPath hg19 (UCSC)LRG1  -     chr19:4537227-4540036 -  19p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LRG1  -     19p13.3   [Description]    (hg38-Dec_2013)
EnsemblLRG1 - 19p13.3 [CytoView hg19]  LRG1 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBILRG1 [Mapview hg19]  LRG1 [Mapview hg38]
OMIM611289   
Gene and transcription
Genbank (Entrez)AB073607 AF403428 AK027382 AK303861 AK314506
RefSeq transcript (Entrez)NM_052972
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011295 NW_004929412
Consensus coding sequences : CCDS (NCBI)LRG1
Cluster EST : UnigeneHs.655559 [ NCBI ]
CGAP (NCI)Hs.655559
Alternative Splicing GalleryENSG00000171236
Gene ExpressionLRG1 [ NCBI-GEO ]   LRG1 [ EBI - ARRAY_EXPRESS ]   LRG1 [ SEEK ]   LRG1 [ MEM ]
Gene Expression Viewer (FireBrowse)LRG1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116844
GTEX Portal (Tissue expression)LRG1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02750   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP02750  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02750
Splice isoforms : SwissVarP02750
PhosPhoSitePlusP02750
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  
Conserved Domain (NCBI)LRG1
DMDM Disease mutations116844
Blocks (Seattle)LRG1
SuperfamilyP02750
Human Protein AtlasENSG00000171236
Peptide AtlasP02750
HPRD10056
IPIIPI00022417   IPI01012772   
Protein Interaction databases
DIP (DOE-UCLA)P02750
IntAct (EBI)P02750
FunCoupENSG00000171236
BioGRIDLRG1
STRING (EMBL)LRG1
ZODIACLRG1
Ontologies - Pathways
QuickGOP02750
Ontology : AmiGOpositive regulation of endothelial cell proliferation  molecular_function  transforming growth factor beta receptor binding  extracellular region  extracellular space  biological_process  membrane  positive regulation of transforming growth factor beta receptor signaling pathway  positive regulation of angiogenesis  brown fat cell differentiation  extracellular exosome  
Ontology : EGO-EBIpositive regulation of endothelial cell proliferation  molecular_function  transforming growth factor beta receptor binding  extracellular region  extracellular space  biological_process  membrane  positive regulation of transforming growth factor beta receptor signaling pathway  positive regulation of angiogenesis  brown fat cell differentiation  extracellular exosome  
NDEx NetworkLRG1
Atlas of Cancer Signalling NetworkLRG1
Wikipedia pathwaysLRG1
Orthology - Evolution
OrthoDB116844
GeneTree (enSembl)ENSG00000171236
Phylogenetic Trees/Animal Genes : TreeFamLRG1
HOVERGENP02750
HOGENOMP02750
Homologs : HomoloGeneLRG1
Homology/Alignments : Family Browser (UCSC)LRG1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRG1
dbVarLRG1
ClinVarLRG1
1000_GenomesLRG1 
Exome Variant ServerLRG1
ExAC (Exome Aggregation Consortium)LRG1 (select the gene name)
Genetic variants : HAPMAP116844
Genomic Variants (DGV)LRG1 [DGVbeta]
DECIPHER (Syndromes)19:4537227-4540036  ENSG00000171236
CONAN: Copy Number AnalysisLRG1 
Mutations
ICGC Data PortalLRG1 
TCGA Data PortalLRG1 
Broad Tumor PortalLRG1
OASIS PortalLRG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRG1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRG1
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LRG1
DgiDB (Drug Gene Interaction Database)LRG1
DoCM (Curated mutations)LRG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRG1 (select a term)
intoGenLRG1
Cancer3DLRG1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611289   
Orphanet
MedgenLRG1
Genetic Testing Registry LRG1
NextProtP02750 [Medical]
TSGene116844
GENETestsLRG1
Huge Navigator LRG1 [HugePedia]
snp3D : Map Gene to Disease116844
BioCentury BCIQLRG1
ClinGenLRG1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD116844
Chemical/Pharm GKB GenePA134919634
Clinical trialLRG1
Miscellaneous
canSAR (ICR)LRG1 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRG1
EVEXLRG1
GoPubMedLRG1
iHOPLRG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:13:44 CET 2017

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