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LRIG2 (leucine rich repeats and immunoglobulin like domains 2)

Identity

Alias_symbol (synonym)KIAA0806
Other aliasLIG-2
LIG2
UFS2
HGNC (Hugo) LRIG2
LocusID (NCBI) 9860
Atlas_Id 52428
Location 1p13.2  [Link to chromosome band 1p13]
Location_base_pair Starts at 113073170 and ends at 113125202 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LRIG2 (1p13.2) / CHIA (1p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRIG2   20889
Cards
Entrez_Gene (NCBI)LRIG2  9860  leucine rich repeats and immunoglobulin like domains 2
AliasesLIG-2; LIG2; UFS2
GeneCards (Weizmann)LRIG2
Ensembl hg19 (Hinxton)ENSG00000198799 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198799 [Gene_View]  chr1:113073170-113125202 [Contig_View]  LRIG2 [Vega]
ICGC DataPortalENSG00000198799
TCGA cBioPortalLRIG2
AceView (NCBI)LRIG2
Genatlas (Paris)LRIG2
WikiGenes9860
SOURCE (Princeton)LRIG2
Genetics Home Reference (NIH)LRIG2
Genomic and cartography
GoldenPath hg38 (UCSC)LRIG2  -     chr1:113073170-113125202 +  1p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRIG2  -     1p13.2   [Description]    (hg19-Feb_2009)
EnsemblLRIG2 - 1p13.2 [CytoView hg19]  LRIG2 - 1p13.2 [CytoView hg38]
Mapping of homologs : NCBILRIG2 [Mapview hg19]  LRIG2 [Mapview hg38]
OMIM608869   615112   
Gene and transcription
Genbank (Entrez)AB018349 AK074825 AK123606 AK291031 AL161998
RefSeq transcript (Entrez)NM_001312686 NM_014813
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRIG2
Cluster EST : UnigeneHs.448972 [ NCBI ]
CGAP (NCI)Hs.448972
Alternative Splicing GalleryENSG00000198799
Gene ExpressionLRIG2 [ NCBI-GEO ]   LRIG2 [ EBI - ARRAY_EXPRESS ]   LRIG2 [ SEEK ]   LRIG2 [ MEM ]
Gene Expression Viewer (FireBrowse)LRIG2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9860
GTEX Portal (Tissue expression)LRIG2
Human Protein AtlasENSG00000198799-LRIG2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94898   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94898  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94898
Splice isoforms : SwissVarO94898
PhosPhoSitePlusO94898
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp   
Domain families : Pfam (Sanger)I-set (PF07679)    LRR_8 (PF13855)    LRRCT (PF01463)   
Domain families : Pfam (NCBI)pfam07679    pfam13855    pfam01463   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  LRR_TYP (SM00369)  LRRCT (SM00082)  
Conserved Domain (NCBI)LRIG2
DMDM Disease mutations9860
Blocks (Seattle)LRIG2
SuperfamilyO94898
Human Protein Atlas [tissue]ENSG00000198799-LRIG2 [tissue]
Peptide AtlasO94898
HPRD12321
IPIIPI00478892   IPI00847210   
Protein Interaction databases
DIP (DOE-UCLA)O94898
IntAct (EBI)O94898
FunCoupENSG00000198799
BioGRIDLRIG2
STRING (EMBL)LRIG2
ZODIACLRIG2
Ontologies - Pathways
QuickGOO94898
Ontology : AmiGOreceptor binding  cytoplasm  plasma membrane  sensory perception of sound  regulation of platelet-derived growth factor receptor signaling pathway  integral component of membrane  growth cone  neuronal cell body  negative regulation of axon regeneration  negative regulation of membrane protein ectodomain proteolysis  innervation  intracellular vesicle  positive regulation of protein localization to cell surface  regulation of neuron migration  
Ontology : EGO-EBIreceptor binding  cytoplasm  plasma membrane  sensory perception of sound  regulation of platelet-derived growth factor receptor signaling pathway  integral component of membrane  growth cone  neuronal cell body  negative regulation of axon regeneration  negative regulation of membrane protein ectodomain proteolysis  innervation  intracellular vesicle  positive regulation of protein localization to cell surface  regulation of neuron migration  
NDEx NetworkLRIG2
Atlas of Cancer Signalling NetworkLRIG2
Wikipedia pathwaysLRIG2
Orthology - Evolution
OrthoDB9860
GeneTree (enSembl)ENSG00000198799
Phylogenetic Trees/Animal Genes : TreeFamLRIG2
HOVERGENO94898
HOGENOMO94898
Homologs : HomoloGeneLRIG2
Homology/Alignments : Family Browser (UCSC)LRIG2
Gene fusions - Rearrangements
Tumor Fusion PortalLRIG2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRIG2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRIG2
dbVarLRIG2
ClinVarLRIG2
1000_GenomesLRIG2 
Exome Variant ServerLRIG2
ExAC (Exome Aggregation Consortium)ENSG00000198799
GNOMAD BrowserENSG00000198799
Genetic variants : HAPMAP9860
Genomic Variants (DGV)LRIG2 [DGVbeta]
DECIPHERLRIG2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRIG2 
Mutations
ICGC Data PortalLRIG2 
TCGA Data PortalLRIG2 
Broad Tumor PortalLRIG2
OASIS PortalLRIG2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRIG2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRIG2
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LRIG2
DgiDB (Drug Gene Interaction Database)LRIG2
DoCM (Curated mutations)LRIG2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRIG2 (select a term)
intoGenLRIG2
Cancer3DLRIG2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608869    615112   
Orphanet2465   
DisGeNETLRIG2
MedgenLRIG2
Genetic Testing Registry LRIG2
NextProtO94898 [Medical]
TSGene9860
GENETestsLRIG2
Target ValidationLRIG2
Huge Navigator LRIG2 [HugePedia]
snp3D : Map Gene to Disease9860
BioCentury BCIQLRIG2
ClinGenLRIG2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9860
Chemical/Pharm GKB GenePA134905053
Clinical trialLRIG2
Miscellaneous
canSAR (ICR)LRIG2 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRIG2
EVEXLRIG2
GoPubMedLRIG2
iHOPLRIG2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:20:53 CET 2017

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