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LRMP (lymphoid restricted membrane protein)

Identity

Alias_nameslymphoid-restricted membrane protein
Alias_symbol (synonym)JAW1
Other alias
HGNC (Hugo) LRMP
LocusID (NCBI) 4033
Atlas_Id 44024
Location 12p12.1  [Link to chromosome band 12p12]
Location_base_pair Starts at 25205181 and ends at 25261269 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LRMP (12p12.1) / BCL6 (3q27.3)LRMP (12p12.1) / MYC (8q24.21)LRMP (12p12.1) / SOX5 (12p12.1)
RERE (1p36.23) / LRMP (12p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(3;12)(q27;p12) LRMP/BCL6
t(8;12)(q24;p12) LRMP/MYC


External links

Nomenclature
HGNC (Hugo)LRMP   6690
Cards
Entrez_Gene (NCBI)LRMP  4033  lymphoid restricted membrane protein
AliasesJAW1
GeneCards (Weizmann)LRMP
Ensembl hg19 (Hinxton)ENSG00000118308 [Gene_View]  chr12:25205181-25261269 [Contig_View]  LRMP [Vega]
Ensembl hg38 (Hinxton)ENSG00000118308 [Gene_View]  chr12:25205181-25261269 [Contig_View]  LRMP [Vega]
ICGC DataPortalENSG00000118308
TCGA cBioPortalLRMP
AceView (NCBI)LRMP
Genatlas (Paris)LRMP
WikiGenes4033
SOURCE (Princeton)LRMP
Genetics Home Reference (NIH)LRMP
Genomic and cartography
GoldenPath hg19 (UCSC)LRMP  -     chr12:25205181-25261269 +  12p12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LRMP  -     12p12.1   [Description]    (hg38-Dec_2013)
EnsemblLRMP - 12p12.1 [CytoView hg19]  LRMP - 12p12.1 [CytoView hg38]
Mapping of homologs : NCBILRMP [Mapview hg19]  LRMP [Mapview hg38]
OMIM602003   
Gene and transcription
Genbank (Entrez)AI949664 AK303103 AK303256 AW206014 AW408383
RefSeq transcript (Entrez)NM_001204126 NM_001204127 NM_006152
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_009714 NW_004929383
Consensus coding sequences : CCDS (NCBI)LRMP
Cluster EST : UnigeneHs.124922 [ NCBI ]
CGAP (NCI)Hs.124922
Alternative Splicing GalleryENSG00000118308
Gene ExpressionLRMP [ NCBI-GEO ]   LRMP [ EBI - ARRAY_EXPRESS ]   LRMP [ SEEK ]   LRMP [ MEM ]
Gene Expression Viewer (FireBrowse)LRMP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4033
GTEX Portal (Tissue expression)LRMP
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12912   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ12912  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ12912
Splice isoforms : SwissVarQ12912
PhosPhoSitePlusQ12912
Domains : Interpro (EBI)MRVI1   
Domain families : Pfam (Sanger)MRVI1 (PF05781)   
Domain families : Pfam (NCBI)pfam05781   
Conserved Domain (NCBI)LRMP
DMDM Disease mutations4033
Blocks (Seattle)LRMP
SuperfamilyQ12912
Human Protein AtlasENSG00000118308
Peptide AtlasQ12912
HPRD03593
IPIIPI00006158   IPI00477421   IPI01021749   IPI01022169   IPI01026206   IPI01026534   IPI01026436   IPI01025864   IPI01025712   IPI01025721   
Protein Interaction databases
DIP (DOE-UCLA)Q12912
IntAct (EBI)Q12912
FunCoupENSG00000118308
BioGRIDLRMP
STRING (EMBL)LRMP
ZODIACLRMP
Ontologies - Pathways
QuickGOQ12912
Ontology : AmiGOspindle pole  immune system process  nuclear envelope  chromosome  endoplasmic reticulum membrane  microtubule organizing center  integral component of plasma membrane  vesicle targeting  vesicle fusion  single fertilization  membrane  integral component of membrane  
Ontology : EGO-EBIspindle pole  immune system process  nuclear envelope  chromosome  endoplasmic reticulum membrane  microtubule organizing center  integral component of plasma membrane  vesicle targeting  vesicle fusion  single fertilization  membrane  integral component of membrane  
NDEx NetworkLRMP
Atlas of Cancer Signalling NetworkLRMP
Wikipedia pathwaysLRMP
Orthology - Evolution
OrthoDB4033
GeneTree (enSembl)ENSG00000118308
Phylogenetic Trees/Animal Genes : TreeFamLRMP
HOVERGENQ12912
HOGENOMQ12912
Homologs : HomoloGeneLRMP
Homology/Alignments : Family Browser (UCSC)LRMP
Gene fusions - Rearrangements
Fusion : MitelmanLRMP/BCL6 [12p12.1/3q27.3]  
Fusion : MitelmanLRMP/MYC [12p12.1/8q24.21]  [t(8;12)(q24;p12)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRMP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRMP
dbVarLRMP
ClinVarLRMP
1000_GenomesLRMP 
Exome Variant ServerLRMP
ExAC (Exome Aggregation Consortium)LRMP (select the gene name)
Genetic variants : HAPMAP4033
Genomic Variants (DGV)LRMP [DGVbeta]
DECIPHER (Syndromes)12:25205181-25261269  ENSG00000118308
CONAN: Copy Number AnalysisLRMP 
Mutations
ICGC Data PortalLRMP 
TCGA Data PortalLRMP 
Broad Tumor PortalLRMP
OASIS PortalLRMP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRMP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRMP
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LRMP
DgiDB (Drug Gene Interaction Database)LRMP
DoCM (Curated mutations)LRMP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRMP (select a term)
intoGenLRMP
Cancer3DLRMP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602003   
Orphanet
MedgenLRMP
Genetic Testing Registry LRMP
NextProtQ12912 [Medical]
TSGene4033
GENETestsLRMP
Huge Navigator LRMP [HugePedia]
snp3D : Map Gene to Disease4033
BioCentury BCIQLRMP
ClinGenLRMP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4033
Chemical/Pharm GKB GenePA30450
Clinical trialLRMP
Miscellaneous
canSAR (ICR)LRMP (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRMP
EVEXLRMP
GoPubMedLRMP
iHOPLRMP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 13:13:45 CET 2017

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