LRP10 (LDL receptor related protein 10)

2016-10-01  

Identity

HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
LRP-10,LRP9,MST087,MSTP087
FUSION GENES

Other Information

Locus ID:

NCBI: 26020
MIM: 609921
HGNC: 14553
Ensembl: ENSG00000197324

Variants:

dbSNP: 26020
ClinVar: 26020
TCGA: ENSG00000197324
COSMIC: LRP10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197324ENST00000359591Q7Z4F1
ENSG00000197324ENST00000546834Q7Z4F1
ENSG00000197324ENST00000551466H0YHW7

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Visual phototransductionREACTOMER-HSA-2187338
Retinoid metabolism and transportREACTOMER-HSA-975634
MetabolismREACTOMER-HSA-1430728
Metabolism of vitamins and cofactorsREACTOMER-HSA-196854
Metabolism of fat-soluble vitaminsREACTOMER-HSA-6806667

References

Pubmed IDYearTitleCitations
227346452012LDLR-related protein 10 (LRP10) regulates amyloid precursor protein (APP) trafficking and processing: evidence for a role in Alzheimer's disease.19
200931062010The low-density lipoprotein receptor-related protein 10 is a negative regulator of the canonical Wnt/beta-catenin signaling pathway.10
298871612018LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study.7
254926832015Mayer-Rokitansky-Küster-Hauser syndrome discordance in monozygotic twins: matrix metalloproteinase 14, low-density lipoprotein receptor-related protein 10, extracellular matrix, and neoangiogenesis genes identified as candidate genes in a tissue-specific mosaicism.6
311472212019LRP10 variants in Parkinson's disease and dementia with Lewy bodies in the South-West of the Netherlands.3
309649572019LRP10 in autosomal-dominant Parkinson's disease.2

Citation

Dessen P

LRP10 (LDL receptor related protein 10)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56379/lrp10