Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LRP3 (LDL receptor related protein 3)

Identity

Alias_nameslow density lipoprotein receptor-related protein 3
Alias_symbol (synonym)LRP-3
hLRp105
Other alias-
HGNC (Hugo) LRP3
LocusID (NCBI) 4037
Atlas_Id 68588
Location 19q13.11  [Link to chromosome band 19q13]
Location_base_pair Starts at 33194693 and ends at 33208867 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LRP3 (19q13.11) / KIF26A (14q32.33)LRP3 (19q13.11) / THAP8 (19q13.12)LRP3 (19q13.11) / VAV1 (19p13.3)
LRP3 THAP8LRP3 VAV1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRP3   6695
Cards
Entrez_Gene (NCBI)LRP3  4037  LDL receptor related protein 3
Aliases
GeneCards (Weizmann)LRP3
Ensembl hg19 (Hinxton)ENSG00000130881 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130881 [Gene_View]  chr19:33194693-33208867 [Contig_View]  LRP3 [Vega]
ICGC DataPortalENSG00000130881
TCGA cBioPortalLRP3
AceView (NCBI)LRP3
Genatlas (Paris)LRP3
WikiGenes4037
SOURCE (Princeton)LRP3
Genetics Home Reference (NIH)LRP3
Genomic and cartography
GoldenPath hg38 (UCSC)LRP3  -     chr19:33194693-33208867 +  19q13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRP3  -     19q13.11   [Description]    (hg19-Feb_2009)
EnsemblLRP3 - 19q13.11 [CytoView hg19]  LRP3 - 19q13.11 [CytoView hg38]
Mapping of homologs : NCBILRP3 [Mapview hg19]  LRP3 [Mapview hg38]
OMIM603159   
Gene and transcription
Genbank (Entrez)AB009462 AF085860 AK074751 AK126750 AK129963
RefSeq transcript (Entrez)NM_002333
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRP3
Cluster EST : UnigeneHs.515340 [ NCBI ]
CGAP (NCI)Hs.515340
Alternative Splicing GalleryENSG00000130881
Gene ExpressionLRP3 [ NCBI-GEO ]   LRP3 [ EBI - ARRAY_EXPRESS ]   LRP3 [ SEEK ]   LRP3 [ MEM ]
Gene Expression Viewer (FireBrowse)LRP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4037
GTEX Portal (Tissue expression)LRP3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75074   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75074  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75074
Splice isoforms : SwissVarO75074
PhosPhoSitePlusO75074
Domaine pattern : Prosite (Expaxy)CUB (PS01180)    LDLRA_1 (PS01209)    LDLRA_2 (PS50068)   
Domains : Interpro (EBI)CUB_dom    LDLR_class-A_CS    LDrepeatLR_classA_rpt   
Domain families : Pfam (Sanger)CUB (PF00431)    Ldl_recept_a (PF00057)   
Domain families : Pfam (NCBI)pfam00431    pfam00057   
Domain families : Smart (EMBL)CUB (SM00042)  LDLa (SM00192)  
Conserved Domain (NCBI)LRP3
DMDM Disease mutations4037
Blocks (Seattle)LRP3
SuperfamilyO75074
Human Protein AtlasENSG00000130881
Peptide AtlasO75074
HPRD04406
IPIIPI00000201   IPI00942651   
Protein Interaction databases
DIP (DOE-UCLA)O75074
IntAct (EBI)O75074
FunCoupENSG00000130881
BioGRIDLRP3
STRING (EMBL)LRP3
ZODIACLRP3
Ontologies - Pathways
QuickGOO75074
Ontology : AmiGOclathrin-coated pit  receptor-mediated endocytosis  integral component of membrane  
Ontology : EGO-EBIclathrin-coated pit  receptor-mediated endocytosis  integral component of membrane  
NDEx NetworkLRP3
Atlas of Cancer Signalling NetworkLRP3
Wikipedia pathwaysLRP3
Orthology - Evolution
OrthoDB4037
GeneTree (enSembl)ENSG00000130881
Phylogenetic Trees/Animal Genes : TreeFamLRP3
HOVERGENO75074
HOGENOMO75074
Homologs : HomoloGeneLRP3
Homology/Alignments : Family Browser (UCSC)LRP3
Gene fusions - Rearrangements
Fusion: TCGALRP3 THAP8
Fusion: TCGALRP3 VAV1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRP3
dbVarLRP3
ClinVarLRP3
1000_GenomesLRP3 
Exome Variant ServerLRP3
ExAC (Exome Aggregation Consortium)LRP3 (select the gene name)
Genetic variants : HAPMAP4037
Genomic Variants (DGV)LRP3 [DGVbeta]
DECIPHERLRP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRP3 
Mutations
ICGC Data PortalLRP3 
TCGA Data PortalLRP3 
Broad Tumor PortalLRP3
OASIS PortalLRP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRP3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRP3
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LRP3
DgiDB (Drug Gene Interaction Database)LRP3
DoCM (Curated mutations)LRP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRP3 (select a term)
intoGenLRP3
Cancer3DLRP3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603159   
Orphanet
MedgenLRP3
Genetic Testing Registry LRP3
NextProtO75074 [Medical]
TSGene4037
GENETestsLRP3
Target ValidationLRP3
Huge Navigator LRP3 [HugePedia]
snp3D : Map Gene to Disease4037
BioCentury BCIQLRP3
ClinGenLRP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4037
Chemical/Pharm GKB GenePA30453
Clinical trialLRP3
Miscellaneous
canSAR (ICR)LRP3 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRP3
EVEXLRP3
GoPubMedLRP3
iHOPLRP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 16:28:52 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.