LRP5 (low density lipoprotein receptor-related protein 5)

Identity

Other names	BMND1
	EVR1
	EVR4
	HBM
	LR3
	LRP7
	OPPG
	OPS
	OPTA1
	VBCH2
HGNC	LRP5
Location	11q13.4
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	LRP5   6697
Entrez_Gene	LRP5  4041  low density lipoprotein receptor-related protein 5
	Cards
GeneCards	LRP5
Ensembl	LRP5 [Search_View]   ENSG00000162337 [Gene_View]
Genatlas	LRP5
GeneLynx	LRP5
eGenome	LRP5
euGene	4041
	Genomic and cartography
GoldenPath	LRP5  -  11q13.4   chr11:67836684-67973319 +  11q13.2   [Description]    (hg18-March_2006)
Ensembl	LRP5 - 11q13.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	LRP5
	Gene and transcription
Genbank	AA279383 [ ENTREZ ]
Genbank	AA953315 [ ENTREZ ]
Genbank	AB017498 [ ENTREZ ]
Genbank	AF064548 [ ENTREZ ]
Genbank	AF077820 [ ENTREZ ]
RefSeq	NM_002335 [ SRS ]    NM_002335 [ ENTREZ ]
RefSeq	AC_000054 [ SRS ]    AC_000054 [ ENTREZ ]
RefSeq	AC_000143 [ SRS ]    AC_000143 [ ENTREZ ]
RefSeq	NC_000011 [ SRS ]    NC_000011 [ ENTREZ ]
RefSeq	NT_033903 [ SRS ]    NT_033903 [ ENTREZ ]
RefSeq	NW_001838025 [ SRS ]    NW_001838025 [ ENTREZ ]
RefSeq	NW_925106 [ SRS ]    NW_925106 [ ENTREZ ]
AceView	LRP5 AceView - NCBI
Unigene	Hs.6347 [ SRS ]    Hs.6347 [ NCBI ]     HS6347 [ spliceNest ]
Fast-db	10945 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O75197 [ SRS]    O75197 [ EXPASY ]     O75197 [ INTERPRO ]     O75197 [ UNIPROT ]
Prosite	PS00022 EGF_1 [ SRS ]    PS00022 EGF_1 [ Expasy ]
Prosite	PS01186 EGF_2 [ SRS ]    PS01186 EGF_2 [ Expasy ]
Prosite	PS50026 EGF_3 [ SRS ]    PS50026 EGF_3 [ Expasy ]
Prosite	PS01187 EGF_CA [ SRS ]    PS01187 EGF_CA [ Expasy ]
Prosite	PS01209 LDLRA_1 [ SRS ]    PS01209 LDLRA_1 [ Expasy ]
Prosite	PS50068 LDLRA_2 [ SRS ]    PS50068 LDLRA_2 [ Expasy ]
Prosite	PS51120 LDLRB [ SRS ]    PS51120 LDLRB [ Expasy ]
Interpro	IPR011042 6-blade_b-propeller_TolB-like [ SRS ]    IPR011042 6-blade_b-propeller_TolB-like [ EBI ]
Interpro	IPR006210 EGF [ SRS ]    IPR006210 EGF [ EBI ]
Interpro	IPR000742 EGF_3 [ SRS ]    IPR000742 EGF_3 [ EBI ]
Interpro	IPR001881 EGF_Ca_bd [ SRS ]    IPR001881 EGF_Ca_bd [ EBI ]
Interpro	IPR006209 EGF_like [ SRS ]    IPR006209 EGF_like [ EBI ]
Interpro	IPR013032 EGF_like_reg_CS [ SRS ]    IPR013032 EGF_like_reg_CS [ EBI ]
Interpro	IPR002172 LDL_rcpt_classA_cys-rich [ SRS ]    IPR002172 LDL_rcpt_classA_cys-rich [ EBI ]
Interpro	IPR000033 LDLR [ SRS ]    IPR000033 LDLR [ EBI ]
Interpro	IPR017049 Low_density_Lipo_rcpt-rel_p5/6 [ SRS ]    IPR017049 Low_density_Lipo_rcpt-rel_p5/6 [ EBI ]
CluSTr	O75197
Pfam	PF00008 EGF [ SRS ]    PF00008 EGF [ Sanger ]    pfam00008 [ NCBI-CDD ]
Pfam	PF00057 Ldl_recept_a [ SRS ]    PF00057 Ldl_recept_a [ Sanger ]    pfam00057 [ NCBI-CDD ]
Pfam	PF00058 Ldl_recept_b [ SRS ]    PF00058 Ldl_recept_b [ Sanger ]    pfam00058 [ NCBI-CDD ]
Smart	SM00181 EGF [EMBL]
Smart	SM00192 LDLa [EMBL]
Smart	SM00135 LY [EMBL]
Blocks	O75197
HPRD	04616
	Protein Interaction databases
DIP	O75197
IntAct	O75197
	Polymorphism : SNP, mutations, diseases
OMIM	144750;166710;259770;601813;601884;603506;607634;607636    [ map ]
GENECLINICS	144750;166710;259770;601813;601884;603506;607634;607636
SNP	LRP5 [dbSNP-NCBI]
SNP	NM_002335 [SNP-NCI]
SNP	LRP5 [GeneSNPs - Utah]  LRP5] [HGBASE - SRS]
HAPMAP	LRP5 [HAPMAP]
COSMIC	LRP5 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	LRP5
	General knowledge
Family Browser	LRP5 [UCSC Family Browser]
SOURCE	NM_002335
SMD	Hs.6347
SAGE	Hs.6347
GO	receptor activity [Amigo]  receptor activity
GO	mitochondrion [Amigo]  mitochondrion
GO	lipid metabolic process [Amigo]  lipid metabolic process
GO	endocytosis [Amigo]  endocytosis
GO	signal transduction [Amigo]  signal transduction
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	positive regulation of cell proliferation [Amigo]  positive regulation of cell proliferation
GO	anterior/posterior pattern formation [Amigo]  anterior/posterior pattern formation
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	Wnt receptor signaling pathway [Amigo]  Wnt receptor signaling pathway
GO	cell migration involved in gastrulation [Amigo]  cell migration involved in gastrulation
GO	embryonic digit morphogenesis [Amigo]  embryonic digit morphogenesis
KEGG	Wnt signaling pathway
PubGene	LRP5
TreeFam	LRP5
CTD	4041 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	LRP5 Related clones (RZPD - Berlin)
	PubMed
PubMed	84 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:18:30 2008