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LRPPRC (leucine rich pentatricopeptide repeat containing)

Identity

Other namesCLONE-23970
GP130
LRP130
LSFC
HGNC (Hugo) LRPPRC
LocusID (NCBI) 10128
Atlas_Id 52241
Location 2p21
Location_base_pair Starts at 44113363 and ends at 44223144 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ALS2CR12 (2q33.1) / LRPPRC (2p21)HACL1 (3p25.1) / LRPPRC (2p21)LRPPRC (2p21) / ADAM12 (10q26.2)
LRPPRC (2p21) / ARL15 (5q11.2)LRPPRC (2p21) / CYTIP (2q24.1)LRPPRC (2p21) / GPC3 (Xq26.2)
LRPPRC (2p21) / LRPPRC (2p21)PPM1K (4q22.1) / LRPPRC (2p21)PRSS23 (11q14.2) / LRPPRC (2p21)
RNF43 (17q22) / LRPPRC (2p21)LRPPRC 2p21 / CYTIP 2q24.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRPPRC   15714
Cards
Entrez_Gene (NCBI)LRPPRC  10128  leucine rich pentatricopeptide repeat containing
GeneCards (Weizmann)LRPPRC
Ensembl hg19 (Hinxton)ENSG00000138095 [Gene_View]  chr2:44113363-44223144 [Contig_View]  LRPPRC [Vega]
Ensembl hg38 (Hinxton)ENSG00000138095 [Gene_View]  chr2:44113363-44223144 [Contig_View]  LRPPRC [Vega]
ICGC DataPortalENSG00000138095
TCGA cBioPortalLRPPRC
AceView (NCBI)LRPPRC
Genatlas (Paris)LRPPRC
WikiGenes10128
SOURCE (Princeton)LRPPRC
Genomic and cartography
GoldenPath hg19 (UCSC)LRPPRC  -     chr2:44113363-44223144 -  2p21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LRPPRC  -     2p21   [Description]    (hg38-Dec_2013)
EnsemblLRPPRC - 2p21 [CytoView hg19]  LRPPRC - 2p21 [CytoView hg38]
Mapping of homologs : NCBILRPPRC [Mapview hg19]  LRPPRC [Mapview hg38]
OMIM220111   607544   
Gene and transcription
Genbank (Entrez)AF052133 AK125781 AK130686 AK290016 AK299869
RefSeq transcript (Entrez)NM_133259
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_008247 NT_022184 NW_004929300
Consensus coding sequences : CCDS (NCBI)LRPPRC
Cluster EST : UnigeneHs.368084 [ NCBI ]
CGAP (NCI)Hs.368084
Alternative Splicing GalleryENSG00000138095
Gene ExpressionLRPPRC [ NCBI-GEO ]   LRPPRC [ EBI - ARRAY_EXPRESS ]   LRPPRC [ SEEK ]   LRPPRC [ MEM ]
Gene Expression Viewer (FireBrowse)LRPPRC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10128
GTEX Portal (Tissue expression)LRPPRC
Protein : pattern, domain, 3D structure
UniProt/SwissProtP42704 (Uniprot)
NextProtP42704  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP42704
Splice isoforms : SwissVarP42704 (Swissvar)
PhosPhoSitePlusP42704
Domaine pattern : Prosite (Expaxy)PPR (PS51375)   
Domains : Interpro (EBI)Pentatricopeptide_repeat    TPR-like_helical_dom   
Domain families : Pfam (Sanger)PPR (PF01535)    PPR_3 (PF13812)   
Domain families : Pfam (NCBI)pfam01535    pfam13812   
DMDM Disease mutations10128
Blocks (Seattle)LRPPRC
SuperfamilyP42704
Human Protein AtlasENSG00000138095
Peptide AtlasP42704
HPRD06343
IPIIPI00783271   IPI01011575   IPI00917568   IPI00917676   IPI00917844   IPI00917975   
Protein Interaction databases
DIP (DOE-UCLA)P42704
IntAct (EBI)P42704
FunCoupENSG00000138095
BioGRIDLRPPRC
STRING (EMBL)LRPPRC
ZODIACLRPPRC
Ontologies - Pathways
QuickGOP42704
Ontology : AmiGOcondensed nuclear chromosome  negative regulation of mitochondrial RNA catabolic process  single-stranded DNA binding  RNA binding  protein binding  nucleus  nuclear inner membrane  nuclear outer membrane  nucleoplasm  mitochondrion  mitochondrion  cytoskeleton  microtubule  transcription, DNA-templated  regulation of transcription, DNA-templated  microtubule binding  membrane  intracellular ribonucleoprotein complex  ubiquitin protein ligase binding  mitochondrial nucleoid  poly(A) RNA binding  mitochondrion transport along microtubule  perinuclear region of cytoplasm  beta-tubulin binding  actin filament binding  mRNA transport  regulation of mitochondrial translation  
Ontology : EGO-EBIcondensed nuclear chromosome  negative regulation of mitochondrial RNA catabolic process  single-stranded DNA binding  RNA binding  protein binding  nucleus  nuclear inner membrane  nuclear outer membrane  nucleoplasm  mitochondrion  mitochondrion  cytoskeleton  microtubule  transcription, DNA-templated  regulation of transcription, DNA-templated  microtubule binding  membrane  intracellular ribonucleoprotein complex  ubiquitin protein ligase binding  mitochondrial nucleoid  poly(A) RNA binding  mitochondrion transport along microtubule  perinuclear region of cytoplasm  beta-tubulin binding  actin filament binding  mRNA transport  regulation of mitochondrial translation  
NDEx Network
Atlas of Cancer Signalling NetworkLRPPRC
Wikipedia pathwaysLRPPRC
Orthology - Evolution
OrthoDB10128
GeneTree (enSembl)ENSG00000138095
Phylogenetic Trees/Animal Genes : TreeFamLRPPRC
Homologs : HomoloGeneLRPPRC
Homology/Alignments : Family Browser (UCSC)LRPPRC
Gene fusions - Rearrangements
Fusion: TCGALRPPRC 2p21 CYTIP 2q24.1 BRCA
Polymorphisms : SNP, variants
NCBI Variation ViewerLRPPRC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRPPRC
dbVarLRPPRC
ClinVarLRPPRC
1000_GenomesLRPPRC 
Exome Variant ServerLRPPRC
ExAC (Exome Aggregation Consortium)LRPPRC (select the gene name)
Genetic variants : HAPMAP10128
Genomic Variants (DGV)LRPPRC [DGVbeta]
Mutations
ICGC Data PortalLRPPRC 
TCGA Data PortalLRPPRC 
Broad Tumor PortalLRPPRC
OASIS PortalLRPPRC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRPPRC 
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch LRPPRC
DgiDB (Drug Gene Interaction Database)LRPPRC
DoCM (Curated mutations)LRPPRC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRPPRC (select a term)
intoGenLRPPRC
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)2:44113363-44223144  ENSG00000138095
CONAN: Copy Number AnalysisLRPPRC 
Mutations and Diseases : HGMDLRPPRC
OMIM220111    607544   
MedgenLRPPRC
Genetic Testing Registry LRPPRC
NextProtP42704 [Medical]
TSGene10128
GENETestsLRPPRC
Huge Navigator LRPPRC [HugePedia]
snp3D : Map Gene to Disease10128
BioCentury BCIQLRPPRC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10128
Chemical/Pharm GKB GenePA30459
Clinical trialLRPPRC
Miscellaneous
canSAR (ICR)LRPPRC (select the gene name)
Probes
Litterature
PubMed88 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRPPRC
EVEXLRPPRC
GoPubMedLRPPRC
iHOPLRPPRC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun May 8 18:53:36 CEST 2016

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