LRRC15 (leucine rich repeat containing 15)

2007-02-01  

Identity

HGNC
LOCATION
3q29
LOCUSID
ALIAS
LIB
FUSION GENES

Other Information

Locus ID:

NCBI: 131578
HGNC: 20818
Ensembl: ENSG00000172061

Variants:

dbSNP: 131578
ClinVar: 131578
TCGA: ENSG00000172061
COSMIC: LRRC15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172061ENST00000347624Q8TF66
ENSG00000172061ENST00000428839Q8TF66

Expression (GTEx)

0
1
2
3
4

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA444552HypertensionDiseaseClinicalAnnotationassociatedPD
PA448499atenololChemicalClinicalAnnotationassociatedPD
PA449899hydrochlorothiazideChemicalClinicalAnnotationassociatedPD
PA450480metoprololChemicalClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
129230582003Identification of a DNA-binding site and transcriptional target for the EWS-WT1(+KTS) oncoprotein.14
297648662018LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody-Drug Conjugates.10
280052672017Human gingiva transcriptome during wound healing.6
183852382008Tumor antigen LRRC15 impedes adenoviral infection: implications for virus-based cancer therapy.5
160989152005Lib, transcriptionally induced in senile plaque-associated astrocytes, promotes glial migration through extracellular matrix.4

Citation

Dessen P

LRRC15 (leucine rich repeat containing 15)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46251/lrrc15