Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 131578
HGNC: 20818
Ensembl: ENSG00000172061
Variants:
dbSNP: 131578
ClinVar: 131578
TCGA: ENSG00000172061
COSMIC: LRRC15
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000172061 | ENST00000347624 | Q8TF66 |
| ENSG00000172061 | ENST00000428839 | Q8TF66 |
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444552 | Hypertension | Disease | ClinicalAnnotation | associated | PD | ||
| PA448499 | atenolol | Chemical | ClinicalAnnotation | associated | PD | ||
| PA449899 | hydrochlorothiazide | Chemical | ClinicalAnnotation | associated | PD | ||
| PA450480 | metoprolol | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38051601 | 2024 | Leucine-Rich Repeat Containing 15-Mediated Cell Adhesion Is Essential for Integrin Signaling in TGF-β1-Induced PDL Fibroblastic Differentiation. | 1 |
| 38566328 | 2024 | Integrated bioinformatics analysis identified leucine rich repeat containing 15 and secreted phosphoprotein 1 as hub genes for calcific aortic valve disease and osteoarthritis. | 2 |
| 38763774 | 2024 | Effect of LRRC15 on autophagy in A549 cells. | 0 |
| 38051601 | 2024 | Leucine-Rich Repeat Containing 15-Mediated Cell Adhesion Is Essential for Integrin Signaling in TGF-β1-Induced PDL Fibroblastic Differentiation. | 1 |
| 38566328 | 2024 | Integrated bioinformatics analysis identified leucine rich repeat containing 15 and secreted phosphoprotein 1 as hub genes for calcific aortic valve disease and osteoarthritis. | 2 |
| 38763774 | 2024 | Effect of LRRC15 on autophagy in A549 cells. | 0 |
| 36625319 | 2023 | RUNX1 Ameliorates Rheumatoid Arthritis Progression through Epigenetic Inhibition of LRRC15. | 2 |
| 36735681 | 2023 | LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein. | 7 |
| 36757924 | 2023 | Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs. | 10 |
| 36625319 | 2023 | RUNX1 Ameliorates Rheumatoid Arthritis Progression through Epigenetic Inhibition of LRRC15. | 2 |
| 36735681 | 2023 | LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein. | 7 |
| 36757924 | 2023 | Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs. | 10 |
| 34726255 | 2022 | Cancer‑associated fibroblast‑derived LRRC15 promotes the migration and invasion of triple‑negative breast cancer cells via Wnt/β‑catenin signalling pathway regulation. | 10 |
| 35896492 | 2022 | [Eukaryotic expression and antigen epitope prediction of the LRRC15 protein in excretory secretory antigens of Taenia solium cysticercus]. | 1 |
| 36228039 | 2022 | LRRC15 inhibits SARS-CoV-2 cellular entry in trans. | 8 |
Citation
Dessen P
LRRC15 (leucine rich repeat containing 15)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46251/lrrc15
