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LRRC15 (leucine rich repeat containing 15)

Identity

Alias_symbol (synonym)LIB
Other alias
HGNC (Hugo) LRRC15
LocusID (NCBI) 131578
Atlas_Id 46251
Location 3q29  [Link to chromosome band 3q29]
Location_base_pair Starts at 194075976 and ends at 194090472 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LRRC15 (3q29) / DYSF (2p13.2)LRRC15 (3q29) / ZBTB38 (3q23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRC15   20818
Cards
Entrez_Gene (NCBI)LRRC15  131578  leucine rich repeat containing 15
AliasesLIB
GeneCards (Weizmann)LRRC15
Ensembl hg19 (Hinxton)ENSG00000172061 [Gene_View]  chr3:194075976-194090472 [Contig_View]  LRRC15 [Vega]
Ensembl hg38 (Hinxton)ENSG00000172061 [Gene_View]  chr3:194075976-194090472 [Contig_View]  LRRC15 [Vega]
ICGC DataPortalENSG00000172061
TCGA cBioPortalLRRC15
AceView (NCBI)LRRC15
Genatlas (Paris)LRRC15
WikiGenes131578
SOURCE (Princeton)LRRC15
Genetics Home Reference (NIH)LRRC15
Genomic and cartography
GoldenPath hg19 (UCSC)LRRC15  -     chr3:194075976-194090472 -  3q29   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LRRC15  -     3q29   [Description]    (hg38-Dec_2013)
EnsemblLRRC15 - 3q29 [CytoView hg19]  LRRC15 - 3q29 [CytoView hg38]
Mapping of homologs : NCBILRRC15 [Mapview hg19]  LRRC15 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB071037 AK022342 AK125112 BC101064 BC101065
RefSeq transcript (Entrez)NM_001135057 NM_130830
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_005612 NW_004929312
Consensus coding sequences : CCDS (NCBI)LRRC15
Cluster EST : UnigeneHs.288467 [ NCBI ]
CGAP (NCI)Hs.288467
Alternative Splicing GalleryENSG00000172061
Gene ExpressionLRRC15 [ NCBI-GEO ]   LRRC15 [ EBI - ARRAY_EXPRESS ]   LRRC15 [ SEEK ]   LRRC15 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)131578
GTEX Portal (Tissue expression)LRRC15
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TF66   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TF66  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TF66
Splice isoforms : SwissVarQ8TF66
PhosPhoSitePlusQ8TF66
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)LRR_1 (PF00560)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam00560    pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
Conserved Domain (NCBI)LRRC15
DMDM Disease mutations131578
Blocks (Seattle)LRRC15
SuperfamilyQ8TF66
Human Protein AtlasENSG00000172061
Peptide AtlasQ8TF66
HPRD10058
IPIIPI00152871   IPI00913924   
Protein Interaction databases
DIP (DOE-UCLA)Q8TF66
IntAct (EBI)Q8TF66
FunCoupENSG00000172061
BioGRIDLRRC15
STRING (EMBL)LRRC15
ZODIACLRRC15
Ontologies - Pathways
QuickGOQ8TF66
Ontology : AmiGOfibronectin binding  protein kinase inhibitor activity  collagen binding  cytoplasm  negative regulation of protein kinase activity  integral component of membrane  cytokine-mediated signaling pathway  positive regulation of cell migration  laminin binding  negative regulation of JAK-STAT cascade  receptor-mediated virion attachment to host cell  extracellular exosome  negative regulation of establishment of protein localization to plasma membrane  
Ontology : EGO-EBIfibronectin binding  protein kinase inhibitor activity  collagen binding  cytoplasm  negative regulation of protein kinase activity  integral component of membrane  cytokine-mediated signaling pathway  positive regulation of cell migration  laminin binding  negative regulation of JAK-STAT cascade  receptor-mediated virion attachment to host cell  extracellular exosome  negative regulation of establishment of protein localization to plasma membrane  
NDEx NetworkLRRC15
Atlas of Cancer Signalling NetworkLRRC15
Wikipedia pathwaysLRRC15
Orthology - Evolution
OrthoDB131578
GeneTree (enSembl)ENSG00000172061
Phylogenetic Trees/Animal Genes : TreeFamLRRC15
HOVERGENQ8TF66
HOGENOMQ8TF66
Homologs : HomoloGeneLRRC15
Homology/Alignments : Family Browser (UCSC)LRRC15
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC15
dbVarLRRC15
ClinVarLRRC15
1000_GenomesLRRC15 
Exome Variant ServerLRRC15
ExAC (Exome Aggregation Consortium)LRRC15 (select the gene name)
Genetic variants : HAPMAP131578
Genomic Variants (DGV)LRRC15 [DGVbeta]
DECIPHER (Syndromes)3:194075976-194090472  ENSG00000172061
CONAN: Copy Number AnalysisLRRC15 
Mutations
ICGC Data PortalLRRC15 
TCGA Data PortalLRRC15 
Broad Tumor PortalLRRC15
OASIS PortalLRRC15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRC15
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LRRC15
DgiDB (Drug Gene Interaction Database)LRRC15
DoCM (Curated mutations)LRRC15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRC15 (select a term)
intoGenLRRC15
Cancer3DLRRC15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenLRRC15
Genetic Testing Registry LRRC15
NextProtQ8TF66 [Medical]
TSGene131578
GENETestsLRRC15
Huge Navigator LRRC15 [HugePedia]
snp3D : Map Gene to Disease131578
BioCentury BCIQLRRC15
ClinGenLRRC15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD131578
Chemical/Pharm GKB GenePA134956867
Clinical trialLRRC15
Miscellaneous
canSAR (ICR)LRRC15 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRC15
EVEXLRRC15
GoPubMedLRRC15
iHOPLRRC15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:13:48 CET 2017

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