Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LRRC15 (leucine rich repeat containing 15)

Identity

Alias_symbol (synonym)LIB
Other alias
HGNC (Hugo) LRRC15
LocusID (NCBI) 131578
Atlas_Id 46251
Location 3q29  [Link to chromosome band 3q29]
Location_base_pair Starts at 194355247 and ends at 194369743 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LRRC15 (3q29) / DYSF (2p13.2)LRRC15 (3q29) / ZBTB38 (3q23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRC15   20818
Cards
Entrez_Gene (NCBI)LRRC15  131578  leucine rich repeat containing 15
AliasesLIB
GeneCards (Weizmann)LRRC15
Ensembl hg19 (Hinxton)ENSG00000172061 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172061 [Gene_View]  chr3:194355247-194369743 [Contig_View]  LRRC15 [Vega]
ICGC DataPortalENSG00000172061
TCGA cBioPortalLRRC15
AceView (NCBI)LRRC15
Genatlas (Paris)LRRC15
WikiGenes131578
SOURCE (Princeton)LRRC15
Genetics Home Reference (NIH)LRRC15
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC15  -     chr3:194355247-194369743 -  3q29   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC15  -     3q29   [Description]    (hg19-Feb_2009)
EnsemblLRRC15 - 3q29 [CytoView hg19]  LRRC15 - 3q29 [CytoView hg38]
Mapping of homologs : NCBILRRC15 [Mapview hg19]  LRRC15 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB071037 AK022342 AK125112 BC101064 BC101065
RefSeq transcript (Entrez)NM_001135057 NM_130830
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRC15
Cluster EST : UnigeneHs.288467 [ NCBI ]
CGAP (NCI)Hs.288467
Alternative Splicing GalleryENSG00000172061
Gene ExpressionLRRC15 [ NCBI-GEO ]   LRRC15 [ EBI - ARRAY_EXPRESS ]   LRRC15 [ SEEK ]   LRRC15 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)131578
GTEX Portal (Tissue expression)LRRC15
Human Protein AtlasENSG00000172061-LRRC15 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TF66   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TF66  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TF66
Splice isoforms : SwissVarQ8TF66
PhosPhoSitePlusQ8TF66
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp   
Domain families : Pfam (Sanger)LRR_1 (PF00560)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam00560    pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  
Conserved Domain (NCBI)LRRC15
DMDM Disease mutations131578
Blocks (Seattle)LRRC15
SuperfamilyQ8TF66
Human Protein Atlas [tissue]ENSG00000172061-LRRC15 [tissue]
Peptide AtlasQ8TF66
HPRD10058
IPIIPI00152871   IPI00913924   
Protein Interaction databases
DIP (DOE-UCLA)Q8TF66
IntAct (EBI)Q8TF66
FunCoupENSG00000172061
BioGRIDLRRC15
STRING (EMBL)LRRC15
ZODIACLRRC15
Ontologies - Pathways
QuickGOQ8TF66
Ontology : AmiGOfibronectin binding  protein kinase inhibitor activity  collagen binding  cytoplasm  negative regulation of protein kinase activity  integral component of membrane  cytokine-mediated signaling pathway  positive regulation of cell migration  laminin binding  negative regulation of JAK-STAT cascade  receptor-mediated virion attachment to host cell  extracellular exosome  negative regulation of establishment of protein localization to plasma membrane  
Ontology : EGO-EBIfibronectin binding  protein kinase inhibitor activity  collagen binding  cytoplasm  negative regulation of protein kinase activity  integral component of membrane  cytokine-mediated signaling pathway  positive regulation of cell migration  laminin binding  negative regulation of JAK-STAT cascade  receptor-mediated virion attachment to host cell  extracellular exosome  negative regulation of establishment of protein localization to plasma membrane  
NDEx NetworkLRRC15
Atlas of Cancer Signalling NetworkLRRC15
Wikipedia pathwaysLRRC15
Orthology - Evolution
OrthoDB131578
GeneTree (enSembl)ENSG00000172061
Phylogenetic Trees/Animal Genes : TreeFamLRRC15
HOVERGENQ8TF66
HOGENOMQ8TF66
Homologs : HomoloGeneLRRC15
Homology/Alignments : Family Browser (UCSC)LRRC15
Gene fusions - Rearrangements
Tumor Fusion PortalLRRC15
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC15
dbVarLRRC15
ClinVarLRRC15
1000_GenomesLRRC15 
Exome Variant ServerLRRC15
ExAC (Exome Aggregation Consortium)ENSG00000172061
GNOMAD BrowserENSG00000172061
Genetic variants : HAPMAP131578
Genomic Variants (DGV)LRRC15 [DGVbeta]
DECIPHERLRRC15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC15 
Mutations
ICGC Data PortalLRRC15 
TCGA Data PortalLRRC15 
Broad Tumor PortalLRRC15
OASIS PortalLRRC15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRC15
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LRRC15
DgiDB (Drug Gene Interaction Database)LRRC15
DoCM (Curated mutations)LRRC15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRC15 (select a term)
intoGenLRRC15
Cancer3DLRRC15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETLRRC15
MedgenLRRC15
Genetic Testing Registry LRRC15
NextProtQ8TF66 [Medical]
TSGene131578
GENETestsLRRC15
Target ValidationLRRC15
Huge Navigator LRRC15 [HugePedia]
snp3D : Map Gene to Disease131578
BioCentury BCIQLRRC15
ClinGenLRRC15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD131578
Chemical/Pharm GKB GenePA134956867
Clinical trialLRRC15
Miscellaneous
canSAR (ICR)LRRC15 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRC15
EVEXLRRC15
GoPubMedLRRC15
iHOPLRRC15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:20:56 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.