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LRRC18 (leucine rich repeat containing 18)

Identity

Alias (NCBI)UNQ933
UNQ9338
VKGE9338
HGNC (Hugo) LRRC18
HGNC Alias symbUNQ933
MGC34773
UNQ9338
VKGE9338
LocusID (NCBI) 474354
Atlas_Id 68597
Location 10q11.23  [Link to chromosome band 10q11]
Location_base_pair Starts at 48909480 and ends at 48939840 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LRRC18   23199
Cards
Entrez_Gene (NCBI)LRRC18    leucine rich repeat containing 18
AliasesUNQ933; UNQ9338; VKGE9338
GeneCards (Weizmann)LRRC18
Ensembl hg19 (Hinxton)ENSG00000165383 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165383 [Gene_View]  ENSG00000165383 [Sequence]  chr10:48909480-48939840 [Contig_View]  LRRC18 [Vega]
ICGC DataPortalENSG00000165383
TCGA cBioPortalLRRC18
AceView (NCBI)LRRC18
Genatlas (Paris)LRRC18
SOURCE (Princeton)LRRC18
Genetics Home Reference (NIH)LRRC18
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC18  -     chr10:48909480-48939840 -  10q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC18  -     10q11.23   [Description]    (hg19-Feb_2009)
GoldenPathLRRC18 - 10q11.23 [CytoView hg19]  LRRC18 - 10q11.23 [CytoView hg38]
ImmunoBaseENSG00000165383
Genome Data Viewer NCBILRRC18 [Mapview hg19]  
OMIM619002   
Gene and transcription
Genbank (Entrez)AY358137 BC036722
RefSeq transcript (Entrez)NM_001006939 NM_001378102
Consensus coding sequences : CCDS (NCBI)LRRC18
Gene ExpressionLRRC18 [ NCBI-GEO ]   LRRC18 [ EBI - ARRAY_EXPRESS ]   LRRC18 [ SEEK ]   LRRC18 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC18 [ Firebrowse - Broad ]
GenevisibleExpression of LRRC18 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)474354
GTEX Portal (Tissue expression)LRRC18
Human Protein AtlasENSG00000165383-LRRC18 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N456   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N456  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N456
PhosPhoSitePlusQ8N456
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR_dom_sf   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  
Conserved Domain (NCBI)LRRC18
SuperfamilyQ8N456
AlphaFold pdb e-kbQ8N456   
Human Protein Atlas [tissue]ENSG00000165383-LRRC18 [tissue]
HPRD17450
Protein Interaction databases
DIP (DOE-UCLA)Q8N456
IntAct (EBI)Q8N456
BioGRIDLRRC18
STRING (EMBL)LRRC18
ZODIACLRRC18
Ontologies - Pathways
QuickGOQ8N456
Ontology : AmiGOprotein binding  cytoplasm  
Ontology : EGO-EBIprotein binding  cytoplasm  
NDEx NetworkLRRC18
Atlas of Cancer Signalling NetworkLRRC18
Wikipedia pathwaysLRRC18
Orthology - Evolution
OrthoDB474354
GeneTree (enSembl)ENSG00000165383
Phylogenetic Trees/Animal Genes : TreeFamLRRC18
Homologs : HomoloGeneLRRC18
Homology/Alignments : Family Browser (UCSC)LRRC18
Gene fusions - Rearrangements
Fusion : QuiverLRRC18
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC18
dbVarLRRC18
ClinVarLRRC18
MonarchLRRC18
1000_GenomesLRRC18 
Exome Variant ServerLRRC18
GNOMAD BrowserENSG00000165383
Varsome BrowserLRRC18
ACMGLRRC18 variants
VarityQ8N456
Genomic Variants (DGV)LRRC18 [DGVbeta]
DECIPHERLRRC18 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC18 
Mutations
ICGC Data PortalLRRC18 
TCGA Data PortalLRRC18 
Broad Tumor PortalLRRC18
OASIS PortalLRRC18 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC18  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLRRC18
Mutations and Diseases : HGMDLRRC18
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLRRC18
DgiDB (Drug Gene Interaction Database)LRRC18
DoCM (Curated mutations)LRRC18
CIViC (Clinical Interpretations of Variants in Cancer)LRRC18
Cancer3DLRRC18
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM619002   
Orphanet
DisGeNETLRRC18
MedgenLRRC18
Genetic Testing Registry LRRC18
NextProtQ8N456 [Medical]
GENETestsLRRC18
Target ValidationLRRC18
Huge Navigator LRRC18 [HugePedia]
ClinGenLRRC18
Clinical trials, drugs, therapy
MyCancerGenomeLRRC18
Protein Interactions : CTDLRRC18
Pharm GKB GenePA134898691
PharosQ8N456
Clinical trialLRRC18
Miscellaneous
canSAR (ICR)LRRC18
HarmonizomeLRRC18
DataMed IndexLRRC18
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLRRC18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:06:13 CEST 2021

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