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LRRC3 (leucine rich repeat containing 3)

Identity

Alias_namesC21orf102
chromosome 21 open reading frame 102
Other aliasC21orf30
LRRC3DN
HGNC (Hugo) LRRC3
LocusID (NCBI) 81543
Atlas_Id 68608
Location 21q22.3  [Link to chromosome band 21q22]
Location_base_pair Starts at 44455486 and ends at 44462196 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRC3   14965
Cards
Entrez_Gene (NCBI)LRRC3  81543  leucine rich repeat containing 3
AliasesC21orf102; C21orf30; LRRC3DN
GeneCards (Weizmann)LRRC3
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr21:44455486-44462196 [Contig_View]  LRRC3 [Vega]
TCGA cBioPortalLRRC3
AceView (NCBI)LRRC3
Genatlas (Paris)LRRC3
WikiGenes81543
SOURCE (Princeton)LRRC3
Genetics Home Reference (NIH)LRRC3
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC3  -     chr21:44455486-44462196 +  21q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC3  -     21q22.3   [Description]    (hg19-Feb_2009)
EnsemblLRRC3 - 21q22.3 [CytoView hg19]  LRRC3 - 21q22.3 [CytoView hg38]
Mapping of homologs : NCBILRRC3 [Mapview hg19]  LRRC3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB058646 AK127604 AL117578 AY061857 AY358120
RefSeq transcript (Entrez)NM_030891
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRC3
Cluster EST : UnigeneHs.542533 [ NCBI ]
CGAP (NCI)Hs.542533
Gene ExpressionLRRC3 [ NCBI-GEO ]   LRRC3 [ EBI - ARRAY_EXPRESS ]   LRRC3 [ SEEK ]   LRRC3 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81543
GTEX Portal (Tissue expression)LRRC3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BY71   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BY71  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BY71
Splice isoforms : SwissVarQ9BY71
PhosPhoSitePlusQ9BY71
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)LRR_1 (PF00560)    LRR_8 (PF13855)    LRRNT (PF01462)   
Domain families : Pfam (NCBI)pfam00560    pfam13855    pfam01462   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRNT (SM00013)  
Conserved Domain (NCBI)LRRC3
DMDM Disease mutations81543
Blocks (Seattle)LRRC3
SuperfamilyQ9BY71
Peptide AtlasQ9BY71
HPRD11286
IPIIPI00008377   IPI01009263   
Protein Interaction databases
DIP (DOE-UCLA)Q9BY71
IntAct (EBI)Q9BY71
BioGRIDLRRC3
STRING (EMBL)LRRC3
ZODIACLRRC3
Ontologies - Pathways
QuickGOQ9BY71
Ontology : AmiGOprotein kinase inhibitor activity  protein binding  cytoplasm  negative regulation of protein kinase activity  integral component of membrane  cytokine-mediated signaling pathway  negative regulation of JAK-STAT cascade  
Ontology : EGO-EBIprotein kinase inhibitor activity  protein binding  cytoplasm  negative regulation of protein kinase activity  integral component of membrane  cytokine-mediated signaling pathway  negative regulation of JAK-STAT cascade  
NDEx NetworkLRRC3
Atlas of Cancer Signalling NetworkLRRC3
Wikipedia pathwaysLRRC3
Orthology - Evolution
OrthoDB81543
Phylogenetic Trees/Animal Genes : TreeFamLRRC3
HOVERGENQ9BY71
HOGENOMQ9BY71
Homologs : HomoloGeneLRRC3
Homology/Alignments : Family Browser (UCSC)LRRC3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC3
dbVarLRRC3
ClinVarLRRC3
1000_GenomesLRRC3 
Exome Variant ServerLRRC3
ExAC (Exome Aggregation Consortium)LRRC3 (select the gene name)
Genetic variants : HAPMAP81543
Genomic Variants (DGV)LRRC3 [DGVbeta]
DECIPHERLRRC3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC3 
Mutations
ICGC Data PortalLRRC3 
TCGA Data PortalLRRC3 
Broad Tumor PortalLRRC3
OASIS PortalLRRC3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRC3
BioMutasearch LRRC3
DgiDB (Drug Gene Interaction Database)LRRC3
DoCM (Curated mutations)LRRC3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRC3 (select a term)
intoGenLRRC3
Cancer3DLRRC3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenLRRC3
Genetic Testing Registry LRRC3
NextProtQ9BY71 [Medical]
TSGene81543
GENETestsLRRC3
Target ValidationLRRC3
Huge Navigator LRRC3 [HugePedia]
snp3D : Map Gene to Disease81543
BioCentury BCIQLRRC3
ClinGenLRRC3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81543
Chemical/Pharm GKB GenePA30462
Clinical trialLRRC3
Miscellaneous
canSAR (ICR)LRRC3 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRC3
EVEXLRRC3
GoPubMedLRRC3
iHOPLRRC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:26:29 CEST 2017

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