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LRRC37A3 (leucine rich repeat containing 37 member A3)

Identity

Alias (NCBI)LRRC37
LRRC37A
HGNC (Hugo) LRRC37A3
HGNC Alias symbFLJ34306
KIAA0563
LocusID (NCBI) 374819
Atlas_Id 68617
Location 17q24.1  [Link to chromosome band 17q24]
Location_base_pair Starts at 64854134 and ends at 64919491 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MAP3K3 (17q23.3) / LRRC37A3 (17q24.1)MRC2 (17q23.2) / LRRC37A3 (17q24.1)SMURF2 (17q23.3) / LRRC37A3 (17q24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LRRC37A3   32427
Cards
Entrez_Gene (NCBI)LRRC37A3    leucine rich repeat containing 37 member A3
AliasesLRRC37; LRRC37A
GeneCards (Weizmann)LRRC37A3
Ensembl hg19 (Hinxton)ENSG00000176809 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176809 [Gene_View]  ENSG00000176809 [Sequence]  chr17:64854134-64919491 [Contig_View]  LRRC37A3 [Vega]
ICGC DataPortalENSG00000176809
TCGA cBioPortalLRRC37A3
AceView (NCBI)LRRC37A3
Genatlas (Paris)LRRC37A3
SOURCE (Princeton)LRRC37A3
Genetics Home Reference (NIH)LRRC37A3
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC37A3  -     chr17:64854134-64919491 -  17q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC37A3  -     17q24.1   [Description]    (hg19-Feb_2009)
GoldenPathLRRC37A3 - 17q24.1 [CytoView hg19]  LRRC37A3 - 17q24.1 [CytoView hg38]
ImmunoBaseENSG00000176809
Genome Data Viewer NCBILRRC37A3 [Mapview hg19]  
OMIM616557   
Gene and transcription
Genbank (Entrez)AB011135 AK091625 AK294371 AK299714 AK308554
RefSeq transcript (Entrez)NM_001303255 NM_199340
Consensus coding sequences : CCDS (NCBI)LRRC37A3
Gene ExpressionLRRC37A3 [ NCBI-GEO ]   LRRC37A3 [ EBI - ARRAY_EXPRESS ]   LRRC37A3 [ SEEK ]   LRRC37A3 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC37A3 [ Firebrowse - Broad ]
GenevisibleExpression of LRRC37A3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)374819
GTEX Portal (Tissue expression)LRRC37A3
Human Protein AtlasENSG00000176809-LRRC37A3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60309   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60309  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60309
PhosPhoSitePlusO60309
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR_dom_sf    LRRC37    LRRC37_N    LRRC37AB_C   
Domain families : Pfam (Sanger)LRR_8 (PF13855)    LRRC37 (PF15779)    LRRC37AB_C (PF14914)   
Domain families : Pfam (NCBI)pfam13855    pfam15779    pfam14914   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  
Conserved Domain (NCBI)LRRC37A3
SuperfamilyO60309
AlphaFold pdb e-kbO60309   
Human Protein Atlas [tissue]ENSG00000176809-LRRC37A3 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)O60309
IntAct (EBI)O60309
BioGRIDLRRC37A3
STRING (EMBL)LRRC37A3
ZODIACLRRC37A3
Ontologies - Pathways
QuickGOO60309
Ontology : AmiGOintegral component of membrane  
Ontology : EGO-EBIintegral component of membrane  
NDEx NetworkLRRC37A3
Atlas of Cancer Signalling NetworkLRRC37A3
Wikipedia pathwaysLRRC37A3
Orthology - Evolution
OrthoDB374819
GeneTree (enSembl)ENSG00000176809
Phylogenetic Trees/Animal Genes : TreeFamLRRC37A3
Homologs : HomoloGeneLRRC37A3
Homology/Alignments : Family Browser (UCSC)LRRC37A3
Gene fusions - Rearrangements
Fusion : QuiverLRRC37A3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC37A3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC37A3
dbVarLRRC37A3
ClinVarLRRC37A3
MonarchLRRC37A3
1000_GenomesLRRC37A3 
Exome Variant ServerLRRC37A3
GNOMAD BrowserENSG00000176809
Varsome BrowserLRRC37A3
ACMGLRRC37A3 variants
VarityO60309
Genomic Variants (DGV)LRRC37A3 [DGVbeta]
DECIPHERLRRC37A3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC37A3 
Mutations
ICGC Data PortalLRRC37A3 
TCGA Data PortalLRRC37A3 
Broad Tumor PortalLRRC37A3
OASIS PortalLRRC37A3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC37A3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLRRC37A3
Mutations and Diseases : HGMDLRRC37A3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLRRC37A3
DgiDB (Drug Gene Interaction Database)LRRC37A3
DoCM (Curated mutations)LRRC37A3
CIViC (Clinical Interpretations of Variants in Cancer)LRRC37A3
Cancer3DLRRC37A3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616557   
Orphanet
DisGeNETLRRC37A3
MedgenLRRC37A3
Genetic Testing Registry LRRC37A3
NextProtO60309 [Medical]
GENETestsLRRC37A3
Target ValidationLRRC37A3
Huge Navigator LRRC37A3 [HugePedia]
ClinGenLRRC37A3
Clinical trials, drugs, therapy
MyCancerGenomeLRRC37A3
Protein Interactions : CTDLRRC37A3
Pharm GKB GenePA162394563
PharosO60309
Clinical trialLRRC37A3
Miscellaneous
canSAR (ICR)LRRC37A3
HarmonizomeLRRC37A3
DataMed IndexLRRC37A3
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLRRC37A3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:06:17 CEST 2021

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