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LRRC37B (leucine rich repeat containing 37B)

Identity

Other aliasLRRC37
HGNC (Hugo) LRRC37B
LocusID (NCBI) 114659
Atlas_Id 54431
Location 17q11.2  [Link to chromosome band 17q11]
Location_base_pair Starts at 30348155 and ends at 30380519 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LRRC37B (17q11.2) / COL18A1 (21q22.3)LRRC37B (17q11.2) / LRRC37B (17q11.2)LRRC37B (17q11.2) / RAD51C (17q22)
NF1 (17q11.2) / LRRC37B (17q11.2)RHOT1 (17q11.2) / LRRC37B (17q11.2)TANC2 (17q23.2) / LRRC37B (17q11.2)
TIAF1 (17q11.2) / LRRC37B (17q11.2)LRRC37B 17q11.2 / RAD51C 17q22RHOT1 17q11.2 / LRRC37B 17q11.2
TANC2 17q23.2 / LRRC37B 17q11.2TIAF1 17q11.2 / LRRC37B 17q11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRC37B   29070
Cards
Entrez_Gene (NCBI)LRRC37B  114659  leucine rich repeat containing 37B
AliasesLRRC37
GeneCards (Weizmann)LRRC37B
Ensembl hg19 (Hinxton)ENSG00000185158 [Gene_View]  chr17:30348155-30380519 [Contig_View]  LRRC37B [Vega]
Ensembl hg38 (Hinxton)ENSG00000185158 [Gene_View]  chr17:30348155-30380519 [Contig_View]  LRRC37B [Vega]
ICGC DataPortalENSG00000185158
TCGA cBioPortalLRRC37B
AceView (NCBI)LRRC37B
Genatlas (Paris)LRRC37B
WikiGenes114659
SOURCE (Princeton)LRRC37B
Genetics Home Reference (NIH)LRRC37B
Genomic and cartography
GoldenPath hg19 (UCSC)LRRC37B  -     chr17:30348155-30380519 +  17q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LRRC37B  -     17q11.2   [Description]    (hg38-Dec_2013)
EnsemblLRRC37B - 17q11.2 [CytoView hg19]  LRRC37B - 17q11.2 [CytoView hg38]
Mapping of homologs : NCBILRRC37B [Mapview hg19]  LRRC37B [Mapview hg38]
OMIM616558   
Gene and transcription
Genbank (Entrez)AI336678 AJ314647 AK123784 AK299772 AK302740
RefSeq transcript (Entrez)NM_001321350 NM_052888
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)LRRC37B
Cluster EST : UnigeneHs.744157 [ NCBI ]
CGAP (NCI)Hs.744157
Alternative Splicing GalleryENSG00000185158
Gene ExpressionLRRC37B [ NCBI-GEO ]   LRRC37B [ EBI - ARRAY_EXPRESS ]   LRRC37B [ SEEK ]   LRRC37B [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC37B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114659
GTEX Portal (Tissue expression)LRRC37B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96QE4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96QE4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96QE4
Splice isoforms : SwissVarQ96QE4
PhosPhoSitePlusQ96QE4
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    LRRC37_N    LRRC37A/B-like    LRRC37AB_C   
Domain families : Pfam (Sanger)LRR_8 (PF13855)    LRRC37 (PF15779)    LRRC37AB_C (PF14914)   
Domain families : Pfam (NCBI)pfam13855    pfam15779    pfam14914   
Conserved Domain (NCBI)LRRC37B
DMDM Disease mutations114659
Blocks (Seattle)LRRC37B
SuperfamilyQ96QE4
Human Protein AtlasENSG00000185158
Peptide AtlasQ96QE4
HPRD14004
IPIIPI00044826   IPI01009286   IPI00783410   IPI00791592   
Protein Interaction databases
DIP (DOE-UCLA)Q96QE4
IntAct (EBI)Q96QE4
FunCoupENSG00000185158
BioGRIDLRRC37B
STRING (EMBL)LRRC37B
ZODIACLRRC37B
Ontologies - Pathways
QuickGOQ96QE4
Ontology : AmiGOcytoplasm  integral component of membrane  
Ontology : EGO-EBIcytoplasm  integral component of membrane  
NDEx NetworkLRRC37B
Atlas of Cancer Signalling NetworkLRRC37B
Wikipedia pathwaysLRRC37B
Orthology - Evolution
OrthoDB114659
GeneTree (enSembl)ENSG00000185158
Phylogenetic Trees/Animal Genes : TreeFamLRRC37B
HOVERGENQ96QE4
HOGENOMQ96QE4
Homologs : HomoloGeneLRRC37B
Homology/Alignments : Family Browser (UCSC)LRRC37B
Gene fusions - Rearrangements
Fusion : MitelmanLRRC37B/RAD51C [17q11.2/17q22]  
Fusion : MitelmanNF1/LRRC37B [17q11.2/17q11.2]  [t(17;17)(q11;q11)]  
Fusion : MitelmanRHOT1/LRRC37B [17q11.2/17q11.2]  [t(17;17)(q11;q11)]  
Fusion : MitelmanTANC2/LRRC37B [17q23.2/17q11.2]  [t(17;17)(q11;q23)]  
Fusion : MitelmanTIAF1/LRRC37B [17q11.2/17q11.2]  [t(17;17)(q11;q11)]  
Fusion: TCGALRRC37B 17q11.2 RAD51C 17q22 BRCA
Fusion: TCGARHOT1 17q11.2 LRRC37B 17q11.2 LUAD
Fusion: TCGATANC2 17q23.2 LRRC37B 17q11.2 BRCA
Fusion: TCGATIAF1 17q11.2 LRRC37B 17q11.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC37B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC37B
dbVarLRRC37B
ClinVarLRRC37B
1000_GenomesLRRC37B 
Exome Variant ServerLRRC37B
ExAC (Exome Aggregation Consortium)LRRC37B (select the gene name)
Genetic variants : HAPMAP114659
Genomic Variants (DGV)LRRC37B [DGVbeta]
DECIPHER (Syndromes)17:30348155-30380519  ENSG00000185158
CONAN: Copy Number AnalysisLRRC37B 
Mutations
ICGC Data PortalLRRC37B 
TCGA Data PortalLRRC37B 
Broad Tumor PortalLRRC37B
OASIS PortalLRRC37B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC37B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRC37B
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LRRC37B
DgiDB (Drug Gene Interaction Database)LRRC37B
DoCM (Curated mutations)LRRC37B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRC37B (select a term)
intoGenLRRC37B
Cancer3DLRRC37B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616558   
Orphanet
MedgenLRRC37B
Genetic Testing Registry LRRC37B
NextProtQ96QE4 [Medical]
TSGene114659
GENETestsLRRC37B
Huge Navigator LRRC37B [HugePedia]
snp3D : Map Gene to Disease114659
BioCentury BCIQLRRC37B
ClinGenLRRC37B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114659
Chemical/Pharm GKB GenePA142671525
Clinical trialLRRC37B
Miscellaneous
canSAR (ICR)LRRC37B (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRC37B
EVEXLRRC37B
GoPubMedLRRC37B
iHOPLRRC37B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:13:49 CET 2017

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