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LRRC37B (leucine rich repeat containing 37B)

Identity

Alias (NCBI)LRRC37
HGNC (Hugo) LRRC37B
HGNC Alias nameKIAA0563-related
LocusID (NCBI) 114659
Atlas_Id 54431
Location 17q11.2  [Link to chromosome band 17q11]
Location_base_pair Starts at 32021108 and ends at 32053487 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LRRC37B (17q11.2) / COL18A1 (21q22.3)LRRC37B (17q11.2) / LRRC37B (17q11.2)LRRC37B (17q11.2) / RAD51C (17q22)
NF1 (17q11.2) / LRRC37B (17q11.2)RHOT1 (17q11.2) / LRRC37B (17q11.2)TANC2 (17q23.2) / LRRC37B (17q11.2)
TIAF1 (17q11.2) / LRRC37B (17q11.2)LRRC37B 17q11.2 / RAD51C 17q22RHOT1 17q11.2 / LRRC37B 17q11.2
TANC2 17q23.2 / LRRC37B 17q11.2TIAF1 17q11.2 / LRRC37B 17q11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(17;17)(q11;q11) NF1/LRRC37B


External links

 

Nomenclature
HGNC (Hugo)LRRC37B   29070
Cards
Entrez_Gene (NCBI)LRRC37B    leucine rich repeat containing 37B
AliasesLRRC37
GeneCards (Weizmann)LRRC37B
Ensembl hg19 (Hinxton)ENSG00000185158 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185158 [Gene_View]  ENSG00000185158 [Sequence]  chr17:32021108-32053487 [Contig_View]  LRRC37B [Vega]
ICGC DataPortalENSG00000185158
TCGA cBioPortalLRRC37B
AceView (NCBI)LRRC37B
Genatlas (Paris)LRRC37B
SOURCE (Princeton)LRRC37B
Genetics Home Reference (NIH)LRRC37B
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC37B  -     chr17:32021108-32053487 +  17q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC37B  -     17q11.2   [Description]    (hg19-Feb_2009)
GoldenPathLRRC37B - 17q11.2 [CytoView hg19]  LRRC37B - 17q11.2 [CytoView hg38]
ImmunoBaseENSG00000185158
Genome Data Viewer NCBILRRC37B [Mapview hg19]  
OMIM616558   
Gene and transcription
Genbank (Entrez)AI336678 AJ314647 AK123784 AK299772 AK302740
RefSeq transcript (Entrez)NM_001321350 NM_052888
Consensus coding sequences : CCDS (NCBI)LRRC37B
Gene ExpressionLRRC37B [ NCBI-GEO ]   LRRC37B [ EBI - ARRAY_EXPRESS ]   LRRC37B [ SEEK ]   LRRC37B [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC37B [ Firebrowse - Broad ]
GenevisibleExpression of LRRC37B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114659
GTEX Portal (Tissue expression)LRRC37B
Human Protein AtlasENSG00000185158-LRRC37B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96QE4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96QE4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96QE4
PhosPhoSitePlusQ96QE4
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR_dom_sf    LRRC37    LRRC37_N    LRRC37AB_C   
Domain families : Pfam (Sanger)LRR_8 (PF13855)    LRRC37 (PF15779)    LRRC37AB_C (PF14914)   
Domain families : Pfam (NCBI)pfam13855    pfam15779    pfam14914   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  
Conserved Domain (NCBI)LRRC37B
SuperfamilyQ96QE4
AlphaFold pdb e-kbQ96QE4   
Human Protein Atlas [tissue]ENSG00000185158-LRRC37B [tissue]
HPRD14004
Protein Interaction databases
DIP (DOE-UCLA)Q96QE4
IntAct (EBI)Q96QE4
BioGRIDLRRC37B
STRING (EMBL)LRRC37B
ZODIACLRRC37B
Ontologies - Pathways
QuickGOQ96QE4
Ontology : AmiGOintegral component of membrane  
Ontology : EGO-EBIintegral component of membrane  
NDEx NetworkLRRC37B
Atlas of Cancer Signalling NetworkLRRC37B
Wikipedia pathwaysLRRC37B
Orthology - Evolution
OrthoDB114659
GeneTree (enSembl)ENSG00000185158
Phylogenetic Trees/Animal Genes : TreeFamLRRC37B
Homologs : HomoloGeneLRRC37B
Homology/Alignments : Family Browser (UCSC)LRRC37B
Gene fusions - Rearrangements
Fusion : MitelmanLRRC37B/RAD51C [17q11.2/17q22]  
Fusion : MitelmanNF1/LRRC37B [17q11.2/17q11.2]  
Fusion : MitelmanRHOT1/LRRC37B [17q11.2/17q11.2]  
Fusion : MitelmanTANC2/LRRC37B [17q23.2/17q11.2]  
Fusion : MitelmanTIAF1/LRRC37B [17q11.2/17q11.2]  
Fusion : QuiverLRRC37B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC37B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC37B
dbVarLRRC37B
ClinVarLRRC37B
MonarchLRRC37B
1000_GenomesLRRC37B 
Exome Variant ServerLRRC37B
GNOMAD BrowserENSG00000185158
Varsome BrowserLRRC37B
ACMGLRRC37B variants
VarityQ96QE4
Genomic Variants (DGV)LRRC37B [DGVbeta]
DECIPHERLRRC37B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC37B 
Mutations
ICGC Data PortalLRRC37B 
TCGA Data PortalLRRC37B 
Broad Tumor PortalLRRC37B
OASIS PortalLRRC37B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC37B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLRRC37B
Mutations and Diseases : HGMDLRRC37B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLRRC37B
DgiDB (Drug Gene Interaction Database)LRRC37B
DoCM (Curated mutations)LRRC37B
CIViC (Clinical Interpretations of Variants in Cancer)LRRC37B
Cancer3DLRRC37B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616558   
Orphanet
DisGeNETLRRC37B
MedgenLRRC37B
Genetic Testing Registry LRRC37B
NextProtQ96QE4 [Medical]
GENETestsLRRC37B
Target ValidationLRRC37B
Huge Navigator LRRC37B [HugePedia]
ClinGenLRRC37B
Clinical trials, drugs, therapy
MyCancerGenomeLRRC37B
Protein Interactions : CTDLRRC37B
Pharm GKB GenePA142671525
PharosQ96QE4
Clinical trialLRRC37B
Miscellaneous
canSAR (ICR)LRRC37B
HarmonizomeLRRC37B
DataMed IndexLRRC37B
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLRRC37B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:17:07 CEST 2021

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