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LRRC3C (leucine rich repeat containing 3C)

Identity

Other alias-
HGNC (Hugo) LRRC3C
LocusID (NCBI) 100505591
Atlas_Id 56551
Location 17q21.1  [Link to chromosome band 17q21]
Location_base_pair Starts at 39941474 and ends at 39y4473 bq from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
B3GNTL1 (17q25.3) / LRRC3C (17q12)WIPF2 (17q21.1) / LRRC3C (17q12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRC3C   40034
Cards
Entrez_Gene (NCBI)LRRC3C  100505591  leucine rich repeat containing 3C
Aliases
GeneCards (Weizmann)LRRC3C
Ensembl hg19 (Hinxton)ENSG00000204913 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204913 [Gene_View]  chr17:39941474-39944734 [Contig_View]  LRRC3C [Vega]
ICGC DataPortalENSG00000204913
TCGA cBioPortalLRRC3C
AceView (NCBI)LRRC3C
Genatlas (Paris)LRRC3C
WikiGenes100505591
SOURCE (Princeton)LRRC3C
Genetics Home Reference (NIH)LRRC3C
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC3C  -     chr17:39941474-39944734 +  17q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC3C  -     17q21.1   [Description]    (hg19-Feb_2009)
EnsemblLRRC3C - 17q21.1 [CytoView hg19]  LRRC3C - 17q21.1 [CytoView hg38]
Mapping of homologs : NCBILRRC3C [Mapview hg19]  LRRC3C [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK091224 DY655553
RefSeq transcript (Entrez)NM_001195545
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRC3C
Cluster EST : UnigeneHs.602305 [ NCBI ]
CGAP (NCI)Hs.602305
Alternative Splicing GalleryENSG00000204913
Gene ExpressionLRRC3C [ NCBI-GEO ]   LRRC3C [ EBI - ARRAY_EXPRESS ]   LRRC3C [ SEEK ]   LRRC3C [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC3C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100505591
GTEX Portal (Tissue expression)LRRC3C
Human Protein AtlasENSG00000204913-LRRC3C [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA6NJW4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA6NJW4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA6NJW4
Splice isoforms : SwissVarA6NJW4
PhosPhoSitePlusA6NJW4
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  
Conserved Domain (NCBI)LRRC3C
DMDM Disease mutations100505591
Blocks (Seattle)LRRC3C
SuperfamilyA6NJW4
Human Protein Atlas [tissue]ENSG00000204913-LRRC3C [tissue]
Peptide AtlasA6NJW4
IPIIPI00746770   
Protein Interaction databases
DIP (DOE-UCLA)A6NJW4
IntAct (EBI)A6NJW4
FunCoupENSG00000204913
BioGRIDLRRC3C
STRING (EMBL)LRRC3C
ZODIACLRRC3C
Ontologies - Pathways
QuickGOA6NJW4
Ontology : AmiGOprotein kinase inhibitor activity  cytoplasm  negative regulation of protein kinase activity  integral component of membrane  cytokine-mediated signaling pathway  negative regulation of JAK-STAT cascade  
Ontology : EGO-EBIprotein kinase inhibitor activity  cytoplasm  negative regulation of protein kinase activity  integral component of membrane  cytokine-mediated signaling pathway  negative regulation of JAK-STAT cascade  
NDEx NetworkLRRC3C
Atlas of Cancer Signalling NetworkLRRC3C
Wikipedia pathwaysLRRC3C
Orthology - Evolution
OrthoDB100505591
GeneTree (enSembl)ENSG00000204913
Phylogenetic Trees/Animal Genes : TreeFamLRRC3C
HOVERGENA6NJW4
HOGENOMA6NJW4
Homologs : HomoloGeneLRRC3C
Homology/Alignments : Family Browser (UCSC)LRRC3C
Gene fusions - Rearrangements
Tumor Fusion PortalLRRC3C
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC3C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC3C
dbVarLRRC3C
ClinVarLRRC3C
1000_GenomesLRRC3C 
Exome Variant ServerLRRC3C
ExAC (Exome Aggregation Consortium)ENSG00000204913
GNOMAD BrowserENSG00000204913
Genetic variants : HAPMAP100505591
Genomic Variants (DGV)LRRC3C [DGVbeta]
DECIPHERLRRC3C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC3C 
Mutations
ICGC Data PortalLRRC3C 
TCGA Data PortalLRRC3C 
Broad Tumor PortalLRRC3C
OASIS PortalLRRC3C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC3C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRC3C
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LRRC3C
DgiDB (Drug Gene Interaction Database)LRRC3C
DoCM (Curated mutations)LRRC3C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRC3C (select a term)
intoGenLRRC3C
Cancer3DLRRC3C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETLRRC3C
MedgenLRRC3C
Genetic Testing Registry LRRC3C
NextProtA6NJW4 [Medical]
TSGene100505591
GENETestsLRRC3C
Target ValidationLRRC3C
Huge Navigator LRRC3C [HugePedia]
snp3D : Map Gene to Disease100505591
BioCentury BCIQLRRC3C
ClinGenLRRC3C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD100505591
Chemical/Pharm GKB GenePA166049056
Clinical trialLRRC3C
Miscellaneous
canSAR (ICR)LRRC3C (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRC3C
EVEXLRRC3C
GoPubMedLRRC3C
iHOPLRRC3C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:20:57 CET 2017

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