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LRRC4 (leucine rich repeat containing 4)

Identity

Other namesNGL-2
HGNC (Hugo) LRRC4
LocusID (NCBI) 64101
Location 7q32.1
Location_base_pair Starts at 127667124 and ends at 127671002 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LRRC4   15586
Entrez_Gene (NCBI)LRRC4  64101  leucine rich repeat containing 4
Cards
GeneCards (Weizmann)LRRC4
Ensembl (Hinxton)ENSG00000128594 [Gene_View]  chr7:127667124-127671002 [Contig_View]  LRRC4 [Vega]
AceView (NCBI)LRRC4
Genatlas (Paris)LRRC4
SOURCE (Stanford)NM_022143
Genomic and cartography
GoldenPath (UCSC)LRRC4  -  7q32.1   chr7:127667124-127671002 -  7q32.1   [Description]    (hg19-Feb_2009)
EnsemblLRRC4 - 7q32.1 [CytoView]
Mapping of homologs : NCBILRRC4 [Mapview]
OMIM610486   
Gene and transcription
Genbank (Entrez)AF196976 AI568859 AJ297858 AK172751 AK314047
RefSeq transcript (SRS)NM_022143
RefSeq transcript (Entrez)NM_022143
RefSeq genomic (SRS)AC_000068 AC_000139 NC_000007 NC_018918 NT_007933 NT_079596 NW_001839071 NW_004078032
RefSeq genomic (Entrez)AC_000068 AC_000139 NC_000007 NC_018918 NT_007933 NT_079596 NW_001839071 NW_004078032
Consensus coding sequences : CCDS (NCBI)LRRC4
Cluster EST : UnigeneHs.655003 [ SRS ] Hs.655003 [ NCBI ]
CGAP (NCI)Hs.655003
Alternative Splicing : Fast-db (Paris)GSHG0028555
Alternative Splicing GalleryENSG00000128594
Gene ExpressionLRRC4 [ NCBI-GEO ]   LRRC4 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HBW1 (SRS) Q9HBW1 (Uniprot)
NextProtQ9HBW1
With graphics : InterProQ9HBW1
Splice isoforms : SwissVarQ9HBW1(Swissvar)
Domaine pattern : Prosite (SRS)IG_LIKE (PS50835)    LRR (PS51450)   
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    LRR (PS51450)   
Domains : Interpro (SRS)Cys-rich_flank_reg_C    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub2    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR-contain_N    LRR_5    Lrrc4   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub2    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR-contain_N    LRR_5    Lrrc4   
Related proteins : CluSTrQ9HBW1
Domain families : Pfam (SRS)I-set (PF07679)    LRR_5 (PF13306)   
Domain families : Pfam (Sanger)I-set (PF07679)    LRR_5 (PF13306)   
Domain families : Pfam (NCBI)pfam07679    pfam13306   
Domain families : Smart (EMBL)IGc2 (SM00408)  LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
DMDM64101
Blocks (Seattle)Q9HBW1
PDB (SRS)2DL9    3ZYI   
PDB (PDBSum)2DL9    3ZYI   
PDB (IMB)2DL9    3ZYI   
PDB (RSDB)2DL9    3ZYI   
Human Protein AtlasENSG00000128594
HPRD10060
IPIIPI00005516   IPI00947006   IPI00947170   IPI00946827   
Protein Interaction databases
DIP (DOE-UCLA)Q9HBW1
IntAct (EBI)Q9HBW1
FunCoupENSG00000128594
REACTOMELRRC4
Protein Interaction Database64101
BioGRIDLRRC4
InParanoidQ9HBW1
Interologous Interaction database Q9HBW1
IntegromeDBLRRC4
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)LRRC4
SNP (GeneSNP Utah)LRRC4
SNP : HGBaseLRRC4
Genetic variants : HAPMAPLRRC4
Somatic Mutations in Cancer : COSMICLRRC4 
CONAN: Copy Number AnalysisLRRC4 
Mutations and Diseases : HGMDLRRC4
OMIM610486   
GENETests610486   
Disease Genetic AssociationLRRC4
Huge Navigator LRRC4 [HugePedia]  LRRC4 [HugeCancerGEM]
Genomic VariantsLRRC4  LRRC4 [DGVbeta]
ClinVarLRRC4
snp3D : Map Gene to Disease64101
General knowledge
Homologs : HomoloGeneLRRC4
Homology/Alignments : Family Browser (UCSC)LRRC4
Phylogenetic Trees/Animal Genes : TreeFamLRRC4
Chemical/Protein Interactions : CTD64101
Chemical/Pharm GKB GenePA30463
Clinical trialLRRC4
Cancer Resource (Charite)ENSG00000128594
Ontology : AmiGOplasma membrane  integral to membrane  cell junction  postsynaptic membrane  
Ontology : EGO-EBIplasma membrane  integral to membrane  cell junction  postsynaptic membrane  
Other databases
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
PubGeneLRRC4
iHOPLRRC4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:48:14 CEST 2013
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