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LRRC4 (leucine rich repeat containing 4)

Identity

Other namesNGL-2
HGNC (Hugo) LRRC4
LocusID (NCBI) 64101
Location 7q32.1
Location_base_pair Starts at 127667124 and ends at 127671002 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LRRC4   15586
Cards
Entrez_Gene (NCBI)LRRC4  64101  leucine rich repeat containing 4
GeneCards (Weizmann)LRRC4
Ensembl (Hinxton)ENSG00000128594 [Gene_View]  chr7:127667124-127671002 [Contig_View]  LRRC4 [Vega]
ICGC DataPortalENSG00000128594
cBioPortalLRRC4
AceView (NCBI)LRRC4
Genatlas (Paris)LRRC4
WikiGenes64101
SOURCE (Princeton)NM_022143
Genomic and cartography
GoldenPath (UCSC)LRRC4  -  7q32.1   chr7:127667124-127671002 -  7q32.1   [Description]    (hg19-Feb_2009)
EnsemblLRRC4 - 7q32.1 [CytoView]
Mapping of homologs : NCBILRRC4 [Mapview]
OMIM610486   
Gene and transcription
Genbank (Entrez)AF196976 AI568859 AJ297858 AK172751 AK314047
RefSeq transcript (Entrez)NM_022143
RefSeq genomic (Entrez)AC_000139 NC_000007 NC_018918 NT_007933 NW_001839071 NW_004929332
Consensus coding sequences : CCDS (NCBI)LRRC4
Cluster EST : UnigeneHs.655003 [ NCBI ]
CGAP (NCI)Hs.655003
Alternative Splicing : Fast-db (Paris)GSHG0028555
Alternative Splicing GalleryENSG00000128594
Gene ExpressionLRRC4 [ NCBI-GEO ]     LRRC4 [ SEEK ]   LRRC4 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HBW1 (Uniprot)
NextProtQ9HBW1  [Medical]
With graphics : InterProQ9HBW1
Splice isoforms : SwissVarQ9HBW1 (Swissvar)
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C [organisation]   Ig-like_dom [organisation]   Ig-like_fold [organisation]   Ig_I-set [organisation]   Ig_sub2 [organisation]   Leu-rich_rpt [organisation]   Leu-rich_rpt_typical-subtyp [organisation]   LRR-contain_N [organisation]   LRR_5 [organisation]   Lrrc4 [organisation]  
Related proteins : CluSTrQ9HBW1
Domain families : Pfam (Sanger)I-set (PF07679)    LRR_5 (PF13306)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam07679    pfam13306    pfam13855   
Domain families : Smart (EMBL)IGc2 (SM00408)  LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
DMDM Disease mutations64101
Blocks (Seattle)Q9HBW1
PDB (SRS)2DL9    3ZYI   
PDB (PDBSum)2DL9    3ZYI   
PDB (IMB)2DL9    3ZYI   
PDB (RSDB)2DL9    3ZYI   
Human Protein AtlasENSG00000128594 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ9HBW1
HPRD10060
IPIIPI00005516   IPI00947006   IPI00947170   IPI00946827   
Protein Interaction databases
DIP (DOE-UCLA)Q9HBW1
IntAct (EBI)Q9HBW1
FunCoupENSG00000128594
BioGRIDLRRC4
InParanoidQ9HBW1
Interologous Interaction database Q9HBW1
IntegromeDBLRRC4
STRING (EMBL)LRRC4
Ontologies - Pathways
Ontology : AmiGOprotein binding  integral component of membrane  cell junction  postsynaptic membrane  
Ontology : EGO-EBIprotein binding  integral component of membrane  cell junction  postsynaptic membrane  
Pathways : KEGGAxon guidance    Cell adhesion molecules (CAMs)   
Protein Interaction DatabaseLRRC4
Wikipedia pathwaysLRRC4
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)LRRC4
snp3D : Map Gene to Disease64101
SNP (GeneSNP Utah)LRRC4
SNP : HGBaseLRRC4
Genetic variants : HAPMAPLRRC4
Exome VariantLRRC4
1000_GenomesLRRC4 
ICGC programENSG00000128594 
Somatic Mutations in Cancer : COSMICLRRC4 
CONAN: Copy Number AnalysisLRRC4 
Mutations and Diseases : HGMDLRRC4
Genomic VariantsLRRC4  LRRC4 [DGVbeta]
dbVarLRRC4
ClinVarLRRC4
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM610486   
MedgenLRRC4
GENETestsLRRC4
Disease Genetic AssociationLRRC4
Huge Navigator LRRC4 [HugePedia]  LRRC4 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneLRRC4
Homology/Alignments : Family Browser (UCSC)LRRC4
Phylogenetic Trees/Animal Genes : TreeFamLRRC4
Chemical/Protein Interactions : CTD64101
Chemical/Pharm GKB GenePA30463
Clinical trialLRRC4
Cancer Resource (Charite)ENSG00000128594
Other databases
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
CoreMineLRRC4
iHOPLRRC4
OncoSearchLRRC4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jul 26 14:37:53 CEST 2014

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