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LRRC45 (leucine rich repeat containing 45)

Identity

Alias_symbol (synonym)MGC20806
Other alias-
HGNC (Hugo) LRRC45
LocusID (NCBI) 201255
Atlas_Id 54433
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 82023302 and ends at 82031151 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LRRC45 (17q25.3) / GCGR (17q25.3)LRRC45 (17q25.3) / GNB1 (1p36.33)LRRC45 (17q25.3) / LRRC45 (17q25.3)
LRRC45 17q25.3 / GNB1 1p36.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)LRRC45   28302
Cards
Entrez_Gene (NCBI)LRRC45  201255  leucine rich repeat containing 45
Aliases
GeneCards (Weizmann)LRRC45
Ensembl hg19 (Hinxton)ENSG00000169683 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169683 [Gene_View]  chr17:82023302-82031151 [Contig_View]  LRRC45 [Vega]
ICGC DataPortalENSG00000169683
TCGA cBioPortalLRRC45
AceView (NCBI)LRRC45
Genatlas (Paris)LRRC45
WikiGenes201255
SOURCE (Princeton)LRRC45
Genetics Home Reference (NIH)LRRC45
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC45  -     chr17:82023302-82031151 +  17q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC45  -     17q25.3   [Description]    (hg19-Feb_2009)
EnsemblLRRC45 - 17q25.3 [CytoView hg19]  LRRC45 - 17q25.3 [CytoView hg38]
Mapping of homologs : NCBILRRC45 [Mapview hg19]  LRRC45 [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC014109 BI837975 JF432130
RefSeq transcript (Entrez)NM_144999
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRC45
Cluster EST : UnigeneHs.143774 [ NCBI ]
CGAP (NCI)Hs.143774
Alternative Splicing GalleryENSG00000169683
Gene ExpressionLRRC45 [ NCBI-GEO ]   LRRC45 [ EBI - ARRAY_EXPRESS ]   LRRC45 [ SEEK ]   LRRC45 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC45 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)201255
GTEX Portal (Tissue expression)LRRC45
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96CN5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96CN5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96CN5
Splice isoforms : SwissVarQ96CN5
PhosPhoSitePlusQ96CN5
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt   
Domain families : Pfam (Sanger)LRR_6 (PF13516)   
Domain families : Pfam (NCBI)pfam13516   
Conserved Domain (NCBI)LRRC45
DMDM Disease mutations201255
Blocks (Seattle)LRRC45
SuperfamilyQ96CN5
Human Protein AtlasENSG00000169683
Peptide AtlasQ96CN5
HPRD14476
IPIIPI00060474   
Protein Interaction databases
DIP (DOE-UCLA)Q96CN5
IntAct (EBI)Q96CN5
FunCoupENSG00000169683
BioGRIDLRRC45
STRING (EMBL)LRRC45
ZODIACLRRC45
Ontologies - Pathways
QuickGOQ96CN5
Ontology : AmiGOprotein binding  nucleoplasm  centrosome  cytosol  plasma membrane  
Ontology : EGO-EBIprotein binding  nucleoplasm  centrosome  cytosol  plasma membrane  
NDEx NetworkLRRC45
Atlas of Cancer Signalling NetworkLRRC45
Wikipedia pathwaysLRRC45
Orthology - Evolution
OrthoDB201255
GeneTree (enSembl)ENSG00000169683
Phylogenetic Trees/Animal Genes : TreeFamLRRC45
HOVERGENQ96CN5
HOGENOMQ96CN5
Homologs : HomoloGeneLRRC45
Homology/Alignments : Family Browser (UCSC)LRRC45
Gene fusions - Rearrangements
Fusion : MitelmanLRRC45/GCGR [17q25.3/17q25.3]  
Fusion : MitelmanLRRC45/GNB1 [17q25.3/1p36.33]  [t(1;17)(p36;q25)]  
Fusion: TCGALRRC45 17q25.3 GNB1 1p36.33 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC45 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC45
dbVarLRRC45
ClinVarLRRC45
1000_GenomesLRRC45 
Exome Variant ServerLRRC45
ExAC (Exome Aggregation Consortium)LRRC45 (select the gene name)
Genetic variants : HAPMAP201255
Genomic Variants (DGV)LRRC45 [DGVbeta]
DECIPHERLRRC45 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC45 
Mutations
ICGC Data PortalLRRC45 
TCGA Data PortalLRRC45 
Broad Tumor PortalLRRC45
OASIS PortalLRRC45 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC45  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRC45
BioMutasearch LRRC45
DgiDB (Drug Gene Interaction Database)LRRC45
DoCM (Curated mutations)LRRC45 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRC45 (select a term)
intoGenLRRC45
Cancer3DLRRC45(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenLRRC45
Genetic Testing Registry LRRC45
NextProtQ96CN5 [Medical]
TSGene201255
GENETestsLRRC45
Target ValidationLRRC45
Huge Navigator LRRC45 [HugePedia]
snp3D : Map Gene to Disease201255
BioCentury BCIQLRRC45
ClinGenLRRC45
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD201255
Chemical/Pharm GKB GenePA142671505
Clinical trialLRRC45
Miscellaneous
canSAR (ICR)LRRC45 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRC45
EVEXLRRC45
GoPubMedLRRC45
iHOPLRRC45
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:58:18 CEST 2017

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