LRRC4C (leucine rich repeat containing 4C)

2014-11-01  

Identity

HGNC
LOCATION
11p12
LOCUSID
ALIAS
NGL-1,NGL1
FUSION GENES

Other Information

Locus ID:

NCBI: 57689
MIM: 608817
HGNC: 29317
Ensembl: ENSG00000148948

Variants:

dbSNP: 57689
ClinVar: 57689
TCGA: ENSG00000148948
COSMIC: LRRC4C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148948ENST00000278198Q9HCJ2
ENSG00000148948ENST00000527150Q9HCJ2
ENSG00000148948ENST00000528697Q9HCJ2
ENSG00000148948ENST00000530763Q9HCJ2
ENSG00000148948ENST00000533474E9PLP4
ENSG00000148948ENST00000619527Q9HCJ2

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Axon guidanceKEGGko04360
Cell adhesion molecules (CAMs)KEGGko04514
Axon guidanceKEGGhsa04360
Cell adhesion molecules (CAMs)KEGGhsa04514

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
145954432003The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons.65
145954432003The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons.65
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
239864732013Trans-induced cis interaction in the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses.15
277599172017Implication of LRRC4C and DPP6 in neurodevelopmental disorders.11
200294092010Association of polymorphisms in the SLIT2 axonal guidance gene with anger in suicide attempters.2

Citation

Dessen P

LRRC4C (leucine rich repeat containing 4C)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68635/lrrc4c