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LRRC59 (leucine rich repeat containing 59)

Identity

Alias_symbol (synonym)PRO1855
FLJ21675
Other aliasp34
HGNC (Hugo) LRRC59
LocusID (NCBI) 55379
Atlas_Id 54434
Location 17q21.33  [Link to chromosome band 17q21]
Location_base_pair Starts at 50381233 and ends at 50397553 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DIP2B (12q13.12) / LRRC59 (17q21.33)H19 (11p15.5) / LRRC59 (17q21.33)LRRC59 (17q21.33) / MAP4K4 (2q11.2)
LRRC59 (17q21.33) / NEUROD2 (17q12)LRRC59 (17q21.33) / NUP107 (12q15)LRRC59 (17q21.33) / SPAG9 (17q21.33)
LRRC75A-AS1 (17p11.2) / LRRC59 (17q21.33)SPAG9 (17q21.33) / LRRC59 (17q21.33)LRRC59 17q21.33 / NUP107 12q15
LRRC59 17q21.33 / SPAG9 17q21.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRC59   28817
Cards
Entrez_Gene (NCBI)LRRC59  55379  leucine rich repeat containing 59
AliasesPRO1855; p34
GeneCards (Weizmann)LRRC59
Ensembl hg19 (Hinxton)ENSG00000108829 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108829 [Gene_View]  chr17:50381233-50397553 [Contig_View]  LRRC59 [Vega]
ICGC DataPortalENSG00000108829
TCGA cBioPortalLRRC59
AceView (NCBI)LRRC59
Genatlas (Paris)LRRC59
WikiGenes55379
SOURCE (Princeton)LRRC59
Genetics Home Reference (NIH)LRRC59
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC59  -     chr17:50381233-50397553 -  17q21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC59  -     17q21.33   [Description]    (hg19-Feb_2009)
EnsemblLRRC59 - 17q21.33 [CytoView hg19]  LRRC59 - 17q21.33 [CytoView hg38]
Mapping of homologs : NCBILRRC59 [Mapview hg19]  LRRC59 [Mapview hg38]
OMIM614854   
Gene and transcription
Genbank (Entrez)AF119857 AK025328 AK130572 AK316593 BC017168
RefSeq transcript (Entrez)NM_018509
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRC59
Cluster EST : UnigeneHs.370927 [ NCBI ]
CGAP (NCI)Hs.370927
Alternative Splicing GalleryENSG00000108829
Gene ExpressionLRRC59 [ NCBI-GEO ]   LRRC59 [ EBI - ARRAY_EXPRESS ]   LRRC59 [ SEEK ]   LRRC59 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC59 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55379
GTEX Portal (Tissue expression)LRRC59
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96AG4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96AG4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96AG4
Splice isoforms : SwissVarQ96AG4
PhosPhoSitePlusQ96AG4
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  
Conserved Domain (NCBI)LRRC59
DMDM Disease mutations55379
Blocks (Seattle)LRRC59
SuperfamilyQ96AG4
Human Protein AtlasENSG00000108829
Peptide AtlasQ96AG4
HPRD15181
IPIIPI00396321   
Protein Interaction databases
DIP (DOE-UCLA)Q96AG4
IntAct (EBI)Q96AG4
FunCoupENSG00000108829
BioGRIDLRRC59
STRING (EMBL)LRRC59
ZODIACLRRC59
Ontologies - Pathways
QuickGOQ96AG4
Ontology : AmiGORNA binding  nuclear envelope  endoplasmic reticulum  endoplasmic reticulum membrane  membrane  integral component of membrane  organelle membrane  mitochondrial nucleoid  cadherin binding  
Ontology : EGO-EBIRNA binding  nuclear envelope  endoplasmic reticulum  endoplasmic reticulum membrane  membrane  integral component of membrane  organelle membrane  mitochondrial nucleoid  cadherin binding  
NDEx NetworkLRRC59
Atlas of Cancer Signalling NetworkLRRC59
Wikipedia pathwaysLRRC59
Orthology - Evolution
OrthoDB55379
GeneTree (enSembl)ENSG00000108829
Phylogenetic Trees/Animal Genes : TreeFamLRRC59
HOVERGENQ96AG4
HOGENOMQ96AG4
Homologs : HomoloGeneLRRC59
Homology/Alignments : Family Browser (UCSC)LRRC59
Gene fusions - Rearrangements
Fusion : MitelmanLRRC59/NEUROD2 [17q21.33/17q12]  
Fusion : MitelmanLRRC59/NUP107 [17q21.33/12q15]  [t(12;17)(q15;q21)]  
Fusion : MitelmanLRRC59/SPAG9 [17q21.33/17q21.33]  [t(17;17)(q21;q21)]  
Fusion: TCGALRRC59 17q21.33 NUP107 12q15 BRCA
Fusion: TCGALRRC59 17q21.33 SPAG9 17q21.33 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC59 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC59
dbVarLRRC59
ClinVarLRRC59
1000_GenomesLRRC59 
Exome Variant ServerLRRC59
ExAC (Exome Aggregation Consortium)LRRC59 (select the gene name)
Genetic variants : HAPMAP55379
Genomic Variants (DGV)LRRC59 [DGVbeta]
DECIPHERLRRC59 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC59 
Mutations
ICGC Data PortalLRRC59 
TCGA Data PortalLRRC59 
Broad Tumor PortalLRRC59
OASIS PortalLRRC59 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC59  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRC59
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LRRC59
DgiDB (Drug Gene Interaction Database)LRRC59
DoCM (Curated mutations)LRRC59 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRC59 (select a term)
intoGenLRRC59
Cancer3DLRRC59(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614854   
Orphanet
MedgenLRRC59
Genetic Testing Registry LRRC59
NextProtQ96AG4 [Medical]
TSGene55379
GENETestsLRRC59
Target ValidationLRRC59
Huge Navigator LRRC59 [HugePedia]
snp3D : Map Gene to Disease55379
BioCentury BCIQLRRC59
ClinGenLRRC59
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55379
Chemical/Pharm GKB GenePA142671518
Clinical trialLRRC59
Miscellaneous
canSAR (ICR)LRRC59 (select the gene name)
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRC59
EVEXLRRC59
GoPubMedLRRC59
iHOPLRRC59
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:16:32 CEST 2017

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