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LRRC6 (leucine rich repeat containing 6)

Identity

Alias_symbol (synonym)TSLRP
LRTP
CILD19
Other alias
HGNC (Hugo) LRRC6
LocusID (NCBI) 23639
Atlas_Id 68641
Location 8q24.22  [Link to chromosome band 8q24]
Location_base_pair Starts at 132570419 and ends at 132675617 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ANKRD40 (17q21.33) / LRRC6 (8q24.22)LRRC6 (8q24.22) / EXT1 (8q24.11)LRRC6 (8q24.22) / ZNF10 (12q24.33)
ZFP36L2 (2p21) / LRRC6 (8q24.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRC6   16725
Cards
Entrez_Gene (NCBI)LRRC6  23639  leucine rich repeat containing 6
AliasesCILD19; LRTP; TSLRP
GeneCards (Weizmann)LRRC6
Ensembl hg19 (Hinxton)ENSG00000129295 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129295 [Gene_View]  chr8:132570419-132675617 [Contig_View]  LRRC6 [Vega]
ICGC DataPortalENSG00000129295
TCGA cBioPortalLRRC6
AceView (NCBI)LRRC6
Genatlas (Paris)LRRC6
WikiGenes23639
SOURCE (Princeton)LRRC6
Genetics Home Reference (NIH)LRRC6
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC6  -     chr8:132570419-132675617 -  8q24.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC6  -     8q24.22   [Description]    (hg19-Feb_2009)
EnsemblLRRC6 - 8q24.22 [CytoView hg19]  LRRC6 - 8q24.22 [CytoView hg38]
Mapping of homologs : NCBILRRC6 [Mapview hg19]  LRRC6 [Mapview hg38]
OMIM614930   614935   
Gene and transcription
Genbank (Entrez)AK313107 AL041128 BC027589 BC047286 BG204280
RefSeq transcript (Entrez)NM_001321961 NM_001321962 NM_001321963 NM_001321964 NM_001321965 NM_001321966 NM_012472
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRC6
Cluster EST : UnigeneHs.618717 [ NCBI ]
CGAP (NCI)Hs.618717
Alternative Splicing GalleryENSG00000129295
Gene ExpressionLRRC6 [ NCBI-GEO ]   LRRC6 [ EBI - ARRAY_EXPRESS ]   LRRC6 [ SEEK ]   LRRC6 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23639
GTEX Portal (Tissue expression)LRRC6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86X45   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86X45  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86X45
Splice isoforms : SwissVarQ86X45
PhosPhoSitePlusQ86X45
Domaine pattern : Prosite (Expaxy)CS (PS51203)    LRR (PS51450)   
Domains : Interpro (EBI)CS_dom    L_dom-like    Leu-rich_rpt    U2A'_phosphoprotein32A_C   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)LRRcap (SM00446)  
Conserved Domain (NCBI)LRRC6
DMDM Disease mutations23639
Blocks (Seattle)LRRC6
SuperfamilyQ86X45
Human Protein AtlasENSG00000129295
Peptide AtlasQ86X45
HPRD10286
IPIIPI00180190   IPI00651698   IPI00984300   IPI00979460   IPI01013624   
Protein Interaction databases
DIP (DOE-UCLA)Q86X45
IntAct (EBI)Q86X45
FunCoupENSG00000129295
BioGRIDLRRC6
STRING (EMBL)LRRC6
ZODIACLRRC6
Ontologies - Pathways
QuickGOQ86X45
Ontology : AmiGOcilium movement  molecular_function  protein binding  cytoplasm  cytoplasm  cilium  male gonad development  flagellated sperm motility  outer dynein arm assembly  inner dynein arm assembly  motile cilium assembly  epithelial cilium movement involved in determination of left/right asymmetry  reproductive system development  
Ontology : EGO-EBIcilium movement  molecular_function  protein binding  cytoplasm  cytoplasm  cilium  male gonad development  flagellated sperm motility  outer dynein arm assembly  inner dynein arm assembly  motile cilium assembly  epithelial cilium movement involved in determination of left/right asymmetry  reproductive system development  
NDEx NetworkLRRC6
Atlas of Cancer Signalling NetworkLRRC6
Wikipedia pathwaysLRRC6
Orthology - Evolution
OrthoDB23639
GeneTree (enSembl)ENSG00000129295
Phylogenetic Trees/Animal Genes : TreeFamLRRC6
HOVERGENQ86X45
HOGENOMQ86X45
Homologs : HomoloGeneLRRC6
Homology/Alignments : Family Browser (UCSC)LRRC6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC6
dbVarLRRC6
ClinVarLRRC6
1000_GenomesLRRC6 
Exome Variant ServerLRRC6
ExAC (Exome Aggregation Consortium)LRRC6 (select the gene name)
Genetic variants : HAPMAP23639
Genomic Variants (DGV)LRRC6 [DGVbeta]
DECIPHERLRRC6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC6 
Mutations
ICGC Data PortalLRRC6 
TCGA Data PortalLRRC6 
Broad Tumor PortalLRRC6
OASIS PortalLRRC6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRC6
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LRRC6
DgiDB (Drug Gene Interaction Database)LRRC6
DoCM (Curated mutations)LRRC6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRC6 (select a term)
intoGenLRRC6
Cancer3DLRRC6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614930    614935   
Orphanet665   
MedgenLRRC6
Genetic Testing Registry LRRC6
NextProtQ86X45 [Medical]
TSGene23639
GENETestsLRRC6
Target ValidationLRRC6
Huge Navigator LRRC6 [HugePedia]
snp3D : Map Gene to Disease23639
BioCentury BCIQLRRC6
ClinGenLRRC6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23639
Chemical/Pharm GKB GenePA134921522
Clinical trialLRRC6
Miscellaneous
canSAR (ICR)LRRC6 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRC6
EVEXLRRC6
GoPubMedLRRC6
iHOPLRRC6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:24:58 CEST 2017

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