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LRRC69 (leucine rich repeat containing 69)

Identity

Alias (NCBI)-
HGNC (Hugo) LRRC69
LocusID (NCBI) 100130742
Atlas_Id 68645
Location 8q21.3  [Link to chromosome band 8q21]
Location_base_pair Starts at 91102619 and ends at 91219254 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AC011997.1 () / LRRC69 (8q21.3)DENND1A (9q33.3) / LRRC69 (8q21.3)OTUD6B (8q21.3) / LRRC69 (8q21.3)
AC011997.1 LRRC69DENND1A LRRC69

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(8;9)(q21;q33) DENND1A/LRRC69

External links

Nomenclature
HGNC (Hugo)LRRC69   34303
Cards
Entrez_Gene (NCBI)LRRC69    leucine rich repeat containing 69
Aliases
GeneCards (Weizmann)LRRC69
Ensembl hg19 (Hinxton)ENSG00000214954 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000214954 [Gene_View]  ENSG00000214954 [Sequence]  chr8:91102619-91219254 [Contig_View]  LRRC69 [Vega]
ICGC DataPortalENSG00000214954
TCGA cBioPortalLRRC69
AceView (NCBI)LRRC69
Genatlas (Paris)LRRC69
SOURCE (Princeton)LRRC69
Genetics Home Reference (NIH)LRRC69
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC69  -     chr8:91102619-91219254 +  8q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC69  -     8q21.3   [Description]    (hg19-Feb_2009)
GoldenPathLRRC69 - 8q21.3 [CytoView hg19]  LRRC69 - 8q21.3 [CytoView hg38]
ImmunoBaseENSG00000214954
genome Data Viewer NCBILRRC69 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK097393 AK130865
RefSeq transcript (Entrez)NM_001129890 NM_001354470
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRC69
Alternative Splicing GalleryENSG00000214954
Gene ExpressionLRRC69 [ NCBI-GEO ]   LRRC69 [ EBI - ARRAY_EXPRESS ]   LRRC69 [ SEEK ]   LRRC69 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC69 [ Firebrowse - Broad ]
GenevisibleExpression of LRRC69 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100130742
GTEX Portal (Tissue expression)LRRC69
Human Protein AtlasENSG00000214954-LRRC69 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZNQ3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZNQ3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZNQ3
Splice isoforms : SwissVarQ6ZNQ3
PhosPhoSitePlusQ6ZNQ3
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR_dom_sf   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  
Conserved Domain (NCBI)LRRC69
Blocks (Seattle)LRRC69
SuperfamilyQ6ZNQ3
Human Protein Atlas [tissue]ENSG00000214954-LRRC69 [tissue]
Peptide AtlasQ6ZNQ3
IPIIPI00893687   IPI00412029   IPI00984769   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZNQ3
IntAct (EBI)Q6ZNQ3
BioGRIDLRRC69
STRING (EMBL)LRRC69
ZODIACLRRC69
Ontologies - Pathways
QuickGOQ6ZNQ3
Ontology : AmiGO
Ontology : EGO-EBI
NDEx NetworkLRRC69
Atlas of Cancer Signalling NetworkLRRC69
Wikipedia pathwaysLRRC69
Orthology - Evolution
OrthoDB100130742
GeneTree (enSembl)ENSG00000214954
Phylogenetic Trees/Animal Genes : TreeFamLRRC69
HOGENOMQ6ZNQ3
Homologs : HomoloGeneLRRC69
Homology/Alignments : Family Browser (UCSC)LRRC69
Gene fusions - Rearrangements
Fusion PortalAC011997.1 LRRC69
Fusion PortalDENND1A LRRC69
Fusion : QuiverLRRC69
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC69 [hg38]
dbVarLRRC69
ClinVarLRRC69
MonarchLRRC69
1000_GenomesLRRC69 
Exome Variant ServerLRRC69
GNOMAD BrowserENSG00000214954
Varsome BrowserLRRC69
Genomic Variants (DGV)LRRC69 [DGVbeta]
DECIPHERLRRC69 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC69 
Mutations
ICGC Data PortalLRRC69 
TCGA Data PortalLRRC69 
Broad Tumor PortalLRRC69
OASIS PortalLRRC69 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC69  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLRRC69
Mutations and Diseases : HGMDLRRC69
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LRRC69
DgiDB (Drug Gene Interaction Database)LRRC69
DoCM (Curated mutations)LRRC69 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRC69 (select a term)
intoGenLRRC69
Cancer3DLRRC69(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETLRRC69
MedgenLRRC69
Genetic Testing Registry LRRC69
NextProtQ6ZNQ3 [Medical]
GENETestsLRRC69
Target ValidationLRRC69
Huge Navigator LRRC69 [HugePedia]
ClinGenLRRC69
Clinical trials, drugs, therapy
MyCancerGenomeLRRC69
Protein Interactions : CTD
Pharm GKB GenePA162394619
Clinical trialLRRC69
Miscellaneous
canSAR (ICR)LRRC69 (select the gene name)
HarmonizomeLRRC69
DataMed IndexLRRC69
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRC69
EVEXLRRC69
GoPubMedLRRC69
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 17:12:14 CET 2020
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