LRRC7 (leucine rich repeat containing 7)

2014-11-01  

Identity

HGNC
LOCATION
1p31.1
LOCUSID
ALIAS
DENSIN
FUSION GENES

Other Information

Locus ID:

NCBI: 57554
MIM: 614453
HGNC: 18531
Ensembl: ENSG00000033122

Variants:

dbSNP: 57554
ClinVar: 57554
TCGA: ENSG00000033122
COSMIC: LRRC7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000033122ENST00000310961A0A075B6E9
ENSG00000033122ENST00000370958B1AKT2
ENSG00000033122ENST00000415775F8WE45
ENSG00000033122ENST00000588515K7ELH5
ENSG00000033122ENST00000608744V9GZ42
ENSG00000033122ENST00000608815V9GY23
ENSG00000033122ENST00000609498V9GYE1
ENSG00000033122ENST00000651989A0A494C1A4

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
117291992002Densin-180 interacts with delta-catenin/neural plakophilin-related armadillo repeat protein at synapses.28
216100802011Characterization of a central Ca2+/calmodulin-dependent protein kinase IIalpha/beta binding domain in densin that selectively modulates glutamate receptor subunit phosphorylation.22
217843002011Genome-wide association study of the child behavior checklist dysregulation profile.15
128192322003A novel protein, densin, expressed by glomerular podocytes.14
175816992007Densin and beta-catenin form a complex and co-localize in cultured podocyte cell junctions.8
179685272008Association analysis of podocyte slit diaphragm genes as candidates for diabetic nephropathy.6
179685272008Association analysis of podocyte slit diaphragm genes as candidates for diabetic nephropathy.6
167419992007Densin and filtrin in the pancreas and in the kidney, targets for humoral autoimmunity in patients with type 1 diabetes.3
170394952007Densin is a novel cell membrane protein of Sertoli cells in the testis.3

Citation

Dessen P

LRRC7 (leucine rich repeat containing 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68646/lrrc7