Atlas of Genetics and Cytogenetics in Oncology and Haematology


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LRRC70 (leucine rich repeat containing 70)

Identity

Alias (NCBI)SLRN
HGNC (Hugo) LRRC70
HGNC Alias symbSLRN
LOC100130733
HGNC Alias namesynleurin
LocusID (NCBI) 100130733
Atlas_Id 68647
Location 5q12.1  [Link to chromosome band 5q12]
Location_base_pair Starts at 62578819 and ends at 62581446 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LRRC70   35155
Cards
Entrez_Gene (NCBI)LRRC70    leucine rich repeat containing 70
AliasesSLRN
GeneCards (Weizmann)LRRC70
Ensembl hg19 (Hinxton)ENSG00000186105 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186105 [Gene_View]  ENSG00000186105 [Sequence]  chr5:62578819-62581446 [Contig_View]  LRRC70 [Vega]
ICGC DataPortalENSG00000186105
TCGA cBioPortalLRRC70
AceView (NCBI)LRRC70
Genatlas (Paris)LRRC70
SOURCE (Princeton)LRRC70
Genetics Home Reference (NIH)LRRC70
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC70  -     chr5:62578819-62581446 +  5q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC70  -     5q12.1   [Description]    (hg19-Feb_2009)
GoldenPathLRRC70 - 5q12.1 [CytoView hg19]  LRRC70 - 5q12.1 [CytoView hg38]
ImmunoBaseENSG00000186105
Genome Data Viewer NCBILRRC70 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK123022 AY280614 AY358733 BC067275 BC110838
RefSeq transcript (Entrez)NM_181506
Consensus coding sequences : CCDS (NCBI)LRRC70
Gene ExpressionLRRC70 [ NCBI-GEO ]   LRRC70 [ EBI - ARRAY_EXPRESS ]   LRRC70 [ SEEK ]   LRRC70 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC70 [ Firebrowse - Broad ]
GenevisibleExpression of LRRC70 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100130733
GTEX Portal (Tissue expression)LRRC70
Human Protein AtlasENSG00000186105-LRRC70 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z2Q7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z2Q7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z2Q7
PhosPhoSitePlusQ7Z2Q7
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR_dom_sf   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  
Conserved Domain (NCBI)LRRC70
SuperfamilyQ7Z2Q7
AlphaFold pdb e-kbQ7Z2Q7   
Human Protein Atlas [tissue]ENSG00000186105-LRRC70 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q7Z2Q7
IntAct (EBI)Q7Z2Q7
BioGRIDLRRC70
STRING (EMBL)LRRC70
ZODIACLRRC70
Ontologies - Pathways
QuickGOQ7Z2Q7
Ontology : AmiGOintegral component of plasma membrane  positive regulation of response to cytokine stimulus  
Ontology : EGO-EBIintegral component of plasma membrane  positive regulation of response to cytokine stimulus  
NDEx NetworkLRRC70
Atlas of Cancer Signalling NetworkLRRC70
Wikipedia pathwaysLRRC70
Orthology - Evolution
OrthoDB100130733
GeneTree (enSembl)ENSG00000186105
Phylogenetic Trees/Animal Genes : TreeFamLRRC70
Homologs : HomoloGeneLRRC70
Homology/Alignments : Family Browser (UCSC)LRRC70
Gene fusions - Rearrangements
Fusion : QuiverLRRC70
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC70 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC70
dbVarLRRC70
ClinVarLRRC70
MonarchLRRC70
1000_GenomesLRRC70 
Exome Variant ServerLRRC70
GNOMAD BrowserENSG00000186105
Varsome BrowserLRRC70
ACMGLRRC70 variants
VarityQ7Z2Q7
Genomic Variants (DGV)LRRC70 [DGVbeta]
DECIPHERLRRC70 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC70 
Mutations
ICGC Data PortalLRRC70 
TCGA Data PortalLRRC70 
Broad Tumor PortalLRRC70
OASIS PortalLRRC70 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC70  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLRRC70
Mutations and Diseases : HGMDLRRC70
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLRRC70
DgiDB (Drug Gene Interaction Database)LRRC70
DoCM (Curated mutations)LRRC70
CIViC (Clinical Interpretations of Variants in Cancer)LRRC70
Cancer3DLRRC70
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETLRRC70
MedgenLRRC70
Genetic Testing Registry LRRC70
NextProtQ7Z2Q7 [Medical]
GENETestsLRRC70
Target ValidationLRRC70
Huge Navigator LRRC70 [HugePedia]
ClinGenLRRC70
Clinical trials, drugs, therapy
MyCancerGenomeLRRC70
Protein Interactions : CTDLRRC70
Pharm GKB GenePA164722127
PharosQ7Z2Q7
Clinical trialLRRC70
Miscellaneous
canSAR (ICR)LRRC70
HarmonizomeLRRC70
DataMed IndexLRRC70
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLRRC70
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:06:23 CEST 2021

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