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LRRC74A (leucine rich repeat containing 74A)

Identity

Alias (NCBI)C14orf166B
LRRC74
HGNC (Hugo) LRRC74A
HGNC Previous nameC14orf166B
 LRRC74
HGNC Previous namechromosome 14 open reading frame 166B
 LRRC74
 leucine rich repeat containing 74
LocusID (NCBI) 145497
Atlas_Id 68651
Location 14q24.3  [Link to chromosome band 14q24]
Location_base_pair Starts at 76826408 and ends at 76870304 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CTNNA3 (10q21.3) / LRRC74A (14q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LRRC74A   23346
Cards
Entrez_Gene (NCBI)LRRC74A    leucine rich repeat containing 74A
AliasesC14orf166B; LRRC74
GeneCards (Weizmann)LRRC74A
Ensembl hg19 (Hinxton)ENSG00000100565 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100565 [Gene_View]  ENSG00000100565 [Sequence]  chr14:76826408-76870304 [Contig_View]  LRRC74A [Vega]
ICGC DataPortalENSG00000100565
TCGA cBioPortalLRRC74A
AceView (NCBI)LRRC74A
Genatlas (Paris)LRRC74A
SOURCE (Princeton)LRRC74A
Genetics Home Reference (NIH)LRRC74A
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC74A  -     chr14:76826408-76870304 +  14q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC74A  -     14q24.3   [Description]    (hg19-Feb_2009)
GoldenPathLRRC74A - 14q24.3 [CytoView hg19]  LRRC74A - 14q24.3 [CytoView hg38]
ImmunoBaseENSG00000100565
Genome Data Viewer NCBILRRC74A [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK058106 AK125722 AK301762 BC062799 BC121159
RefSeq transcript (Entrez)NM_001385106 NM_001385107 NM_001385108 NM_194287
Consensus coding sequences : CCDS (NCBI)LRRC74A
Gene ExpressionLRRC74A [ NCBI-GEO ]   LRRC74A [ EBI - ARRAY_EXPRESS ]   LRRC74A [ SEEK ]   LRRC74A [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC74A [ Firebrowse - Broad ]
GenevisibleExpression of LRRC74A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)145497
GTEX Portal (Tissue expression)LRRC74A
Human Protein AtlasENSG00000100565-LRRC74A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ0VAA2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ0VAA2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ0VAA2
PhosPhoSitePlusQ0VAA2
Domains : Interpro (EBI)Leu-rich_rpt    LRR_dom_sf   
Domain families : Pfam (Sanger)LRR_6 (PF13516)   
Domain families : Pfam (NCBI)pfam13516   
Conserved Domain (NCBI)LRRC74A
SuperfamilyQ0VAA2
AlphaFold pdb e-kbQ0VAA2   
Human Protein Atlas [tissue]ENSG00000100565-LRRC74A [tissue]
HPRD12621
Protein Interaction databases
DIP (DOE-UCLA)Q0VAA2
IntAct (EBI)Q0VAA2
BioGRIDLRRC74A
STRING (EMBL)LRRC74A
ZODIACLRRC74A
Ontologies - Pathways
QuickGOQ0VAA2
Ontology : AmiGO
Ontology : EGO-EBI
NDEx NetworkLRRC74A
Atlas of Cancer Signalling NetworkLRRC74A
Wikipedia pathwaysLRRC74A
Orthology - Evolution
OrthoDB145497
GeneTree (enSembl)ENSG00000100565
Phylogenetic Trees/Animal Genes : TreeFamLRRC74A
Homologs : HomoloGeneLRRC74A
Homology/Alignments : Family Browser (UCSC)LRRC74A
Gene fusions - Rearrangements
Fusion : QuiverLRRC74A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC74A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC74A
dbVarLRRC74A
ClinVarLRRC74A
MonarchLRRC74A
1000_GenomesLRRC74A 
Exome Variant ServerLRRC74A
GNOMAD BrowserENSG00000100565
Varsome BrowserLRRC74A
ACMGLRRC74A variants
VarityQ0VAA2
Genomic Variants (DGV)LRRC74A [DGVbeta]
DECIPHERLRRC74A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC74A 
Mutations
ICGC Data PortalLRRC74A 
TCGA Data PortalLRRC74A 
Broad Tumor PortalLRRC74A
OASIS PortalLRRC74A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRC74A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLRRC74A
Mutations and Diseases : HGMDLRRC74A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLRRC74A
DgiDB (Drug Gene Interaction Database)LRRC74A
DoCM (Curated mutations)LRRC74A
CIViC (Clinical Interpretations of Variants in Cancer)LRRC74A
Cancer3DLRRC74A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETLRRC74A
MedgenLRRC74A
Genetic Testing Registry LRRC74A
NextProtQ0VAA2 [Medical]
GENETestsLRRC74A
Target ValidationLRRC74A
Huge Navigator LRRC74A [HugePedia]
ClinGenLRRC74A
Clinical trials, drugs, therapy
MyCancerGenomeLRRC74A
Protein Interactions : CTDLRRC74A
Pharm GKB GenePA134862662
PharosQ0VAA2
Clinical trialLRRC74A
Miscellaneous
canSAR (ICR)LRRC74A
HarmonizomeLRRC74A
DataMed IndexLRRC74A
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLRRC74A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:06:24 CEST 2021

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