Atlas of Genetics and Cytogenetics in Oncology and Haematology


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LRRC74B (leucine rich repeat containing 74B)

Identity

Other alias-
HGNC (Hugo) LRRC74B
LocusID (NCBI) 400891
Atlas_Id 68652
Location 22q11.21  [Link to chromosome band 22q11]
Location_base_pair Starts at 21045960 and ends at 21064168 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRC74B   34301
Cards
Entrez_Gene (NCBI)LRRC74B  400891  leucine rich repeat containing 74B
Aliases
GeneCards (Weizmann)LRRC74B
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr22:21045960-21064168 [Contig_View]  LRRC74B [Vega]
TCGA cBioPortalLRRC74B
AceView (NCBI)LRRC74B
Genatlas (Paris)LRRC74B
WikiGenes400891
SOURCE (Princeton)LRRC74B
Genetics Home Reference (NIH)LRRC74B
Genomic and cartography
GoldenPath hg38 (UCSC)LRRC74B  -     chr22:21045960-21064168 +  22q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRC74B  -     22q11.21   [Description]    (hg19-Feb_2009)
EnsemblLRRC74B - 22q11.21 [CytoView hg19]  LRRC74B - 22q11.21 [CytoView hg38]
Mapping of homologs : NCBILRRC74B [Mapview hg19]  LRRC74B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK128646 BC028231 BC036220 BC140948 BC140950
RefSeq transcript (Entrez)NM_001013675 NM_001291006
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRC74B
Cluster EST : UnigeneHs.291198 [ NCBI ]
CGAP (NCI)Hs.291198
Gene ExpressionLRRC74B [ NCBI-GEO ]   LRRC74B [ EBI - ARRAY_EXPRESS ]   LRRC74B [ SEEK ]   LRRC74B [ MEM ]
Gene Expression Viewer (FireBrowse)LRRC74B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)400891
GTEX Portal (Tissue expression)LRRC74B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZQY2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZQY2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZQY2
Splice isoforms : SwissVarQ6ZQY2
PhosPhoSitePlusQ6ZQY2
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt   
Domain families : Pfam (Sanger)LRR_6 (PF13516)   
Domain families : Pfam (NCBI)pfam13516   
Conserved Domain (NCBI)LRRC74B
DMDM Disease mutations400891
Blocks (Seattle)LRRC74B
SuperfamilyQ6ZQY2
Peptide AtlasQ6ZQY2
HPRD18419
IPIIPI00847652   IPI00884933   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZQY2
IntAct (EBI)Q6ZQY2
BioGRIDLRRC74B
STRING (EMBL)LRRC74B
ZODIACLRRC74B
Ontologies - Pathways
QuickGOQ6ZQY2
Ontology : AmiGO
Ontology : EGO-EBI
NDEx NetworkLRRC74B
Atlas of Cancer Signalling NetworkLRRC74B
Wikipedia pathwaysLRRC74B
Orthology - Evolution
OrthoDB400891
Phylogenetic Trees/Animal Genes : TreeFamLRRC74B
HOVERGENQ6ZQY2
HOGENOMQ6ZQY2
Homologs : HomoloGeneLRRC74B
Homology/Alignments : Family Browser (UCSC)LRRC74B
Gene fusions - Rearrangements
Tumor Fusion PortalLRRC74B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRC74B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRC74B
dbVarLRRC74B
ClinVarLRRC74B
1000_GenomesLRRC74B 
Exome Variant ServerLRRC74B
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP400891
Genomic Variants (DGV)LRRC74B [DGVbeta]
DECIPHERLRRC74B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRC74B 
Mutations
ICGC Data PortalLRRC74B 
TCGA Data PortalLRRC74B 
Broad Tumor PortalLRRC74B
OASIS PortalLRRC74B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDLRRC74B
BioMutasearch LRRC74B
DgiDB (Drug Gene Interaction Database)LRRC74B
DoCM (Curated mutations)LRRC74B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRC74B (select a term)
intoGenLRRC74B
Cancer3DLRRC74B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETLRRC74B
MedgenLRRC74B
Genetic Testing Registry LRRC74B
NextProtQ6ZQY2 [Medical]
TSGene400891
GENETestsLRRC74B
Target ValidationLRRC74B
Huge Navigator LRRC74B [HugePedia]
snp3D : Map Gene to Disease400891
BioCentury BCIQLRRC74B
ClinGenLRRC74B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD400891
Chemical/Pharm GKB GenePA166123701
Clinical trialLRRC74B
Miscellaneous
canSAR (ICR)LRRC74B (select the gene name)
Probes
Litterature
PubMed1 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRC74B
EVEXLRRC74B
GoPubMedLRRC74B
iHOPLRRC74B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:43:55 CET 2017

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