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LRRCC1 (leucine rich repeat and coiled-coil centrosomal protein 1)

Identity

Alias (NCBI)CLERC
CLERK
SAP2
VFL1
HGNC (Hugo) LRRCC1
HGNC Alias symbKIAA1764
CLERC
VFL1
HGNC Alias namecentrosomal leucine-rich repeat and coiled-coil containing protein
 variable number of flagella 1 homolog (Chlamydomonas)
HGNC Previous nameleucine rich repeat and coiled-coil domain containing 1
LocusID (NCBI) 85444
Atlas_Id 68661
Location 8q21.2  [Link to chromosome band 8q21]
Location_base_pair Starts at 85107238 and ends at 85146079 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ASAP1 (8q24.21) / LRRCC1 (8q21.2)LRRCC1 (8q21.2) / CNTN5 (11q22.1)LRRCC1 (8q21.2) / MTG2 (20q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)LRRCC1   29373
Cards
Entrez_Gene (NCBI)LRRCC1    leucine rich repeat and coiled-coil centrosomal protein 1
AliasesCLERC; CLERK; SAP2; VFL1
GeneCards (Weizmann)LRRCC1
Ensembl hg19 (Hinxton)ENSG00000133739 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000133739 [Gene_View]  ENSG00000133739 [Sequence]  chr8:85107238-85146079 [Contig_View]  LRRCC1 [Vega]
ICGC DataPortalENSG00000133739
TCGA cBioPortalLRRCC1
AceView (NCBI)LRRCC1
Genatlas (Paris)LRRCC1
SOURCE (Princeton)LRRCC1
Genetics Home Reference (NIH)LRRCC1
Genomic and cartography
GoldenPath hg38 (UCSC)LRRCC1  -     chr8:85107238-85146079 +  8q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRCC1  -     8q21.2   [Description]    (hg19-Feb_2009)
GoldenPathLRRCC1 - 8q21.2 [CytoView hg19]  LRRCC1 - 8q21.2 [CytoView hg38]
ImmunoBaseENSG00000133739
Genome Data Viewer NCBILRRCC1 [Mapview hg19]  
OMIM617791   
Gene and transcription
Genbank (Entrez)AA000990 AB051551 AK056185 AK057990 AK300234
RefSeq transcript (Entrez)NM_001077501 NM_001349636 NM_001349637 NM_001349638 NM_001349639 NM_033402
Consensus coding sequences : CCDS (NCBI)LRRCC1
Gene ExpressionLRRCC1 [ NCBI-GEO ]   LRRCC1 [ EBI - ARRAY_EXPRESS ]   LRRCC1 [ SEEK ]   LRRCC1 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRCC1 [ Firebrowse - Broad ]
GenevisibleExpression of LRRCC1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85444
GTEX Portal (Tissue expression)LRRCC1
Human Protein AtlasENSG00000133739-LRRCC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C099   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9C099  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9C099
PhosPhoSitePlusQ9C099
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Leu-rich_rpt    LRR_dom_sf   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)LRRCC1
SuperfamilyQ9C099
AlphaFold pdb e-kbQ9C099   
Human Protein Atlas [tissue]ENSG00000133739-LRRCC1 [tissue]
HPRD11160
Protein Interaction databases
DIP (DOE-UCLA)Q9C099
IntAct (EBI)Q9C099
BioGRIDLRRCC1
STRING (EMBL)LRRCC1
ZODIACLRRCC1
Ontologies - Pathways
QuickGOQ9C099
Ontology : AmiGOcytoplasm  centrosome  centrosome  centriole  cell cycle  cell division  
Ontology : EGO-EBIcytoplasm  centrosome  centrosome  centriole  cell cycle  cell division  
NDEx NetworkLRRCC1
Atlas of Cancer Signalling NetworkLRRCC1
Wikipedia pathwaysLRRCC1
Orthology - Evolution
OrthoDB85444
GeneTree (enSembl)ENSG00000133739
Phylogenetic Trees/Animal Genes : TreeFamLRRCC1
Homologs : HomoloGeneLRRCC1
Homology/Alignments : Family Browser (UCSC)LRRCC1
Gene fusions - Rearrangements
Fusion : QuiverLRRCC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRCC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRCC1
dbVarLRRCC1
ClinVarLRRCC1
MonarchLRRCC1
1000_GenomesLRRCC1 
Exome Variant ServerLRRCC1
GNOMAD BrowserENSG00000133739
Varsome BrowserLRRCC1
ACMGLRRCC1 variants
VarityQ9C099
Genomic Variants (DGV)LRRCC1 [DGVbeta]
DECIPHERLRRCC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRCC1 
Mutations
ICGC Data PortalLRRCC1 
TCGA Data PortalLRRCC1 
Broad Tumor PortalLRRCC1
OASIS PortalLRRCC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRCC1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLRRCC1
Mutations and Diseases : HGMDLRRCC1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLRRCC1
DgiDB (Drug Gene Interaction Database)LRRCC1
DoCM (Curated mutations)LRRCC1
CIViC (Clinical Interpretations of Variants in Cancer)LRRCC1
Cancer3DLRRCC1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617791   
Orphanet
DisGeNETLRRCC1
MedgenLRRCC1
Genetic Testing Registry LRRCC1
NextProtQ9C099 [Medical]
GENETestsLRRCC1
Target ValidationLRRCC1
Huge Navigator LRRCC1 [HugePedia]
ClinGenLRRCC1
Clinical trials, drugs, therapy
MyCancerGenomeLRRCC1
Protein Interactions : CTDLRRCC1
Pharm GKB GenePA142671519
PharosQ9C099
Clinical trialLRRCC1
Miscellaneous
canSAR (ICR)LRRCC1
HarmonizomeLRRCC1
DataMed IndexLRRCC1
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLRRCC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:06:26 CEST 2021
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