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LRRN1 (leucine rich repeat neuronal 1)

Identity

Alias_namesimmunoglobulin and leucine rich repeat domains 3
Alias_symbol (synonym)FIGLER3
Other aliasNLRR-1
HGNC (Hugo) LRRN1
LocusID (NCBI) 57633
Atlas_Id 56264
Location 3p26.2  [Link to chromosome band 3p26]
Location_base_pair Starts at 3799431 and ends at 3849834 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRN1   20980
Cards
Entrez_Gene (NCBI)LRRN1  57633  leucine rich repeat neuronal 1
AliasesFIGLER3; NLRR-1
GeneCards (Weizmann)LRRN1
Ensembl hg19 (Hinxton)ENSG00000175928 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175928 [Gene_View]  chr3:3799431-3849834 [Contig_View]  LRRN1 [Vega]
ICGC DataPortalENSG00000175928
TCGA cBioPortalLRRN1
AceView (NCBI)LRRN1
Genatlas (Paris)LRRN1
WikiGenes57633
SOURCE (Princeton)LRRN1
Genetics Home Reference (NIH)LRRN1
Genomic and cartography
GoldenPath hg38 (UCSC)LRRN1  -     chr3:3799431-3849834 +  3p26.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRN1  -     3p26.2   [Description]    (hg19-Feb_2009)
EnsemblLRRN1 - 3p26.2 [CytoView hg19]  LRRN1 - 3p26.2 [CytoView hg38]
Mapping of homologs : NCBILRRN1 [Mapview hg19]  LRRN1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB040930 AB074161 AK023273 AK291717 AM392530
RefSeq transcript (Entrez)NM_001324188 NM_001324189 NM_020873
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRN1
Cluster EST : UnigeneHs.737660 [ NCBI ]
CGAP (NCI)Hs.737660
Alternative Splicing GalleryENSG00000175928
Gene ExpressionLRRN1 [ NCBI-GEO ]   LRRN1 [ EBI - ARRAY_EXPRESS ]   LRRN1 [ SEEK ]   LRRN1 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57633
GTEX Portal (Tissue expression)LRRN1
Human Protein AtlasENSG00000175928-LRRN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UXK5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UXK5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UXK5
Splice isoforms : SwissVarQ6UXK5
PhosPhoSitePlusQ6UXK5
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    IG_LIKE (PS50835)    LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    FN3_dom    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp   
Domain families : Pfam (Sanger)I-set (PF07679)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam07679    pfam13855   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  LRR_TYP (SM00369)  LRRCT (SM00082)  
Conserved Domain (NCBI)LRRN1
DMDM Disease mutations57633
Blocks (Seattle)LRRN1
SuperfamilyQ6UXK5
Human Protein Atlas [tissue]ENSG00000175928-LRRN1 [tissue]
Peptide AtlasQ6UXK5
HPRD14320
IPIIPI00021485   
Protein Interaction databases
DIP (DOE-UCLA)Q6UXK5
IntAct (EBI)Q6UXK5
FunCoupENSG00000175928
BioGRIDLRRN1
STRING (EMBL)LRRN1
ZODIACLRRN1
Ontologies - Pathways
QuickGOQ6UXK5
Ontology : AmiGOproteinaceous extracellular matrix  extracellular space  axonogenesis  integral component of membrane  positive regulation of synapse assembly  
Ontology : EGO-EBIproteinaceous extracellular matrix  extracellular space  axonogenesis  integral component of membrane  positive regulation of synapse assembly  
NDEx NetworkLRRN1
Atlas of Cancer Signalling NetworkLRRN1
Wikipedia pathwaysLRRN1
Orthology - Evolution
OrthoDB57633
GeneTree (enSembl)ENSG00000175928
Phylogenetic Trees/Animal Genes : TreeFamLRRN1
HOVERGENQ6UXK5
HOGENOMQ6UXK5
Homologs : HomoloGeneLRRN1
Homology/Alignments : Family Browser (UCSC)LRRN1
Gene fusions - Rearrangements
Tumor Fusion PortalLRRN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRN1
dbVarLRRN1
ClinVarLRRN1
1000_GenomesLRRN1 
Exome Variant ServerLRRN1
ExAC (Exome Aggregation Consortium)ENSG00000175928
GNOMAD BrowserENSG00000175928
Genetic variants : HAPMAP57633
Genomic Variants (DGV)LRRN1 [DGVbeta]
DECIPHERLRRN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRN1 
Mutations
ICGC Data PortalLRRN1 
TCGA Data PortalLRRN1 
Broad Tumor PortalLRRN1
OASIS PortalLRRN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LRRN1
DgiDB (Drug Gene Interaction Database)LRRN1
DoCM (Curated mutations)LRRN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRN1 (select a term)
intoGenLRRN1
Cancer3DLRRN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETLRRN1
MedgenLRRN1
Genetic Testing Registry LRRN1
NextProtQ6UXK5 [Medical]
TSGene57633
GENETestsLRRN1
Target ValidationLRRN1
Huge Navigator LRRN1 [HugePedia]
snp3D : Map Gene to Disease57633
BioCentury BCIQLRRN1
ClinGenLRRN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57633
Chemical/Pharm GKB GenePA134935557
Clinical trialLRRN1
Miscellaneous
canSAR (ICR)LRRN1 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRN1
EVEXLRRN1
GoPubMedLRRN1
iHOPLRRN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:21:00 CET 2017

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