Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LRRN2 (leucine rich repeat neuronal 2)

Identity

Alias_namesLRRN5
leucine rich repeat neuronal 5
Alias_symbol (synonym)GAC1
LRANK1
FIGLER7
Other alias
HGNC (Hugo) LRRN2
LocusID (NCBI) 10446
Atlas_Id 41206
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 204586303 and ends at 204654481 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NFASC (1q32.1) / LRRN2 (1q32.1)NFASC 1q32.1 / LRRN2 1q32.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRN2   16914
Cards
Entrez_Gene (NCBI)LRRN2  10446  leucine rich repeat neuronal 2
AliasesFIGLER7; GAC1; LRANK1; LRRN5
GeneCards (Weizmann)LRRN2
Ensembl hg19 (Hinxton)ENSG00000170382 [Gene_View]  chr1:204586303-204654481 [Contig_View]  LRRN2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000170382 [Gene_View]  chr1:204586303-204654481 [Contig_View]  LRRN2 [Vega]
ICGC DataPortalENSG00000170382
TCGA cBioPortalLRRN2
AceView (NCBI)LRRN2
Genatlas (Paris)LRRN2
WikiGenes10446
SOURCE (Princeton)LRRN2
Genetics Home Reference (NIH)LRRN2
Genomic and cartography
GoldenPath hg19 (UCSC)LRRN2  -     chr1:204586303-204654481 -  1q32.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LRRN2  -     1q32.1   [Description]    (hg38-Dec_2013)
EnsemblLRRN2 - 1q32.1 [CytoView hg19]  LRRN2 - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBILRRN2 [Mapview hg19]  LRRN2 [Mapview hg38]
OMIM605492   
Gene and transcription
Genbank (Entrez)AF030435 AK001246 AK024867 AK226055 AK312408
RefSeq transcript (Entrez)NM_006338 NM_201630
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)LRRN2
Cluster EST : UnigeneHs.26312 [ NCBI ]
CGAP (NCI)Hs.26312
Alternative Splicing GalleryENSG00000170382
Gene ExpressionLRRN2 [ NCBI-GEO ]   LRRN2 [ EBI - ARRAY_EXPRESS ]   LRRN2 [ SEEK ]   LRRN2 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRN2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10446
GTEX Portal (Tissue expression)LRRN2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75325   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75325  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75325
Splice isoforms : SwissVarO75325
PhosPhoSitePlusO75325
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub2    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)I-set (PF07679)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam07679    pfam13855   
Domain families : Smart (EMBL)IGc2 (SM00408)  LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
Conserved Domain (NCBI)LRRN2
DMDM Disease mutations10446
Blocks (Seattle)LRRN2
SuperfamilyO75325
Human Protein AtlasENSG00000170382
Peptide AtlasO75325
HPRD16109
IPIIPI00025256   IPI00979356   
Protein Interaction databases
DIP (DOE-UCLA)O75325
IntAct (EBI)O75325
FunCoupENSG00000170382
BioGRIDLRRN2
STRING (EMBL)LRRN2
ZODIACLRRN2
Ontologies - Pathways
QuickGOO75325
Ontology : AmiGOreceptor activity  cell adhesion  signal transduction  axonogenesis  integral component of membrane  
Ontology : EGO-EBIreceptor activity  cell adhesion  signal transduction  axonogenesis  integral component of membrane  
NDEx NetworkLRRN2
Atlas of Cancer Signalling NetworkLRRN2
Wikipedia pathwaysLRRN2
Orthology - Evolution
OrthoDB10446
GeneTree (enSembl)ENSG00000170382
Phylogenetic Trees/Animal Genes : TreeFamLRRN2
HOVERGENO75325
HOGENOMO75325
Homologs : HomoloGeneLRRN2
Homology/Alignments : Family Browser (UCSC)LRRN2
Gene fusions - Rearrangements
Fusion : MitelmanNFASC/LRRN2 [1q32.1/1q32.1]  [t(1;1)(q32;q32)]  
Fusion: TCGANFASC 1q32.1 LRRN2 1q32.1 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRN2
dbVarLRRN2
ClinVarLRRN2
1000_GenomesLRRN2 
Exome Variant ServerLRRN2
ExAC (Exome Aggregation Consortium)LRRN2 (select the gene name)
Genetic variants : HAPMAP10446
Genomic Variants (DGV)LRRN2 [DGVbeta]
DECIPHER (Syndromes)1:204586303-204654481  ENSG00000170382
CONAN: Copy Number AnalysisLRRN2 
Mutations
ICGC Data PortalLRRN2 
TCGA Data PortalLRRN2 
Broad Tumor PortalLRRN2
OASIS PortalLRRN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRN2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRN2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LRRN2
DgiDB (Drug Gene Interaction Database)LRRN2
DoCM (Curated mutations)LRRN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRN2 (select a term)
intoGenLRRN2
Cancer3DLRRN2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605492   
Orphanet
MedgenLRRN2
Genetic Testing Registry LRRN2
NextProtO75325 [Medical]
TSGene10446
GENETestsLRRN2
Huge Navigator LRRN2 [HugePedia]
snp3D : Map Gene to Disease10446
BioCentury BCIQLRRN2
ClinGenLRRN2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10446
Chemical/Pharm GKB GenePA162394661
Clinical trialLRRN2
Miscellaneous
canSAR (ICR)LRRN2 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRN2
EVEXLRRN2
GoPubMedLRRN2
iHOPLRRN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:13:51 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.