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LRRN3 (leucine rich repeat neuronal 3)

Identity

Alias_namesimmunoglobulin and leucine rich repeat domains 5
Alias_symbol (synonym)NLRR3
FLJ11129
FIGLER5
Other aliasNLRR-3
HGNC (Hugo) LRRN3
LocusID (NCBI) 54674
Atlas_Id 56417
Location 7q31.1  [Link to chromosome band 7q31]
Location_base_pair Starts at 111091006 and ends at 111125453 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRN3   17200
Cards
Entrez_Gene (NCBI)LRRN3  54674  leucine rich repeat neuronal 3
AliasesFIGLER5; NLRR-3; NLRR3
GeneCards (Weizmann)LRRN3
Ensembl hg19 (Hinxton)ENSG00000173114 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173114 [Gene_View]  chr7:111091006-111125453 [Contig_View]  LRRN3 [Vega]
ICGC DataPortalENSG00000173114
TCGA cBioPortalLRRN3
AceView (NCBI)LRRN3
Genatlas (Paris)LRRN3
WikiGenes54674
SOURCE (Princeton)LRRN3
Genetics Home Reference (NIH)LRRN3
Genomic and cartography
GoldenPath hg38 (UCSC)LRRN3  -     chr7:111091006-111125453 +  7q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRN3  -     7q31.1   [Description]    (hg19-Feb_2009)
EnsemblLRRN3 - 7q31.1 [CytoView hg19]  LRRN3 - 7q31.1 [CytoView hg38]
Mapping of homologs : NCBILRRN3 [Mapview hg19]  LRRN3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB060967 AF134481 AK001991 AK292556 AL442092
RefSeq transcript (Entrez)NM_001099658 NM_001099660 NM_018334
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRN3
Cluster EST : UnigeneHs.3781 [ NCBI ]
CGAP (NCI)Hs.3781
Alternative Splicing GalleryENSG00000173114
Gene ExpressionLRRN3 [ NCBI-GEO ]   LRRN3 [ EBI - ARRAY_EXPRESS ]   LRRN3 [ SEEK ]   LRRN3 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRN3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54674
GTEX Portal (Tissue expression)LRRN3
Human Protein AtlasENSG00000173114-LRRN3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H3W5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H3W5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H3W5
Splice isoforms : SwissVarQ9H3W5
PhosPhoSitePlusQ9H3W5
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    IG_LIKE (PS50835)    LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    FN3_dom    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)fn3 (PF00041)    I-set (PF07679)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam00041    pfam07679    pfam13855   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
Conserved Domain (NCBI)LRRN3
DMDM Disease mutations54674
Blocks (Seattle)LRRN3
SuperfamilyQ9H3W5
Human Protein Atlas [tissue]ENSG00000173114-LRRN3 [tissue]
Peptide AtlasQ9H3W5
HPRD14321
IPIIPI00465126   IPI00924926   
Protein Interaction databases
DIP (DOE-UCLA)Q9H3W5
IntAct (EBI)Q9H3W5
FunCoupENSG00000173114
BioGRIDLRRN3
STRING (EMBL)LRRN3
ZODIACLRRN3
Ontologies - Pathways
QuickGOQ9H3W5
Ontology : AmiGOproteinaceous extracellular matrix  extracellular space  axonogenesis  integral component of membrane  positive regulation of synapse assembly  
Ontology : EGO-EBIproteinaceous extracellular matrix  extracellular space  axonogenesis  integral component of membrane  positive regulation of synapse assembly  
NDEx NetworkLRRN3
Atlas of Cancer Signalling NetworkLRRN3
Wikipedia pathwaysLRRN3
Orthology - Evolution
OrthoDB54674
GeneTree (enSembl)ENSG00000173114
Phylogenetic Trees/Animal Genes : TreeFamLRRN3
HOVERGENQ9H3W5
HOGENOMQ9H3W5
Homologs : HomoloGeneLRRN3
Homology/Alignments : Family Browser (UCSC)LRRN3
Gene fusions - Rearrangements
Tumor Fusion PortalLRRN3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRN3
dbVarLRRN3
ClinVarLRRN3
1000_GenomesLRRN3 
Exome Variant ServerLRRN3
ExAC (Exome Aggregation Consortium)ENSG00000173114
GNOMAD BrowserENSG00000173114
Genetic variants : HAPMAP54674
Genomic Variants (DGV)LRRN3 [DGVbeta]
DECIPHERLRRN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRN3 
Mutations
ICGC Data PortalLRRN3 
TCGA Data PortalLRRN3 
Broad Tumor PortalLRRN3
OASIS PortalLRRN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRN3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRN3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LRRN3
DgiDB (Drug Gene Interaction Database)LRRN3
DoCM (Curated mutations)LRRN3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRN3 (select a term)
intoGenLRRN3
Cancer3DLRRN3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETLRRN3
MedgenLRRN3
Genetic Testing Registry LRRN3
NextProtQ9H3W5 [Medical]
TSGene54674
GENETestsLRRN3
Target ValidationLRRN3
Huge Navigator LRRN3 [HugePedia]
snp3D : Map Gene to Disease54674
BioCentury BCIQLRRN3
ClinGenLRRN3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54674
Chemical/Pharm GKB GenePA30468
Clinical trialLRRN3
Miscellaneous
canSAR (ICR)LRRN3 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRN3
EVEXLRRN3
GoPubMedLRRN3
iHOPLRRN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:21:00 CET 2017

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