LRRN3 (leucine rich repeat neuronal 3)

2016-10-01  

Identity

HGNC
LOCATION
7q31.1
LOCUSID
ALIAS
FIGLER5,NLRR-3,NLRR3

Other Information

Locus ID:

NCBI: 54674
HGNC: 17200
Ensembl: ENSG00000173114

Variants:

dbSNP: 54674
ClinVar: 54674
TCGA: ENSG00000173114
COSMIC: LRRN3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173114ENST00000308478Q9H3W5
ENSG00000173114ENST00000308478A4D0T1
ENSG00000173114ENST00000421101E7EW58
ENSG00000173114ENST00000422987Q9H3W5
ENSG00000173114ENST00000422987A4D0T1
ENSG00000173114ENST00000451085Q9H3W5
ENSG00000173114ENST00000451085A4D0T1

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
206782492010Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry.21
219085752011Expression of NLRR3 orphan receptor gene is negatively regulated by MYCN and Miz-1, and its downregulation is associated with unfavorable outcome in neuroblastoma.9
252567442014Intracellular fragment of NLRR3 (NLRR3-ICD) stimulates ATRA-dependent neuroblastoma differentiation.1

Citation

Dessen P

LRRN3 (leucine rich repeat neuronal 3)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56417/lrrn3