Atlas of Genetics and Cytogenetics in Oncology and Haematology


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LRRTM1 (leucine rich repeat transmembrane neuronal 1)

Identity

Alias_symbol (synonym)FLJ32082
Other alias-
HGNC (Hugo) LRRTM1
LocusID (NCBI) 347730
Atlas_Id 68671
Location 2p12  [Link to chromosome band 2p12]
Location_base_pair Starts at 80301878 and ends at 80304362 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRTM1   19408
Cards
Entrez_Gene (NCBI)LRRTM1  347730  leucine rich repeat transmembrane neuronal 1
Aliases
GeneCards (Weizmann)LRRTM1
Ensembl hg19 (Hinxton)ENSG00000162951 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162951 [Gene_View]  chr2:80301878-80304362 [Contig_View]  LRRTM1 [Vega]
ICGC DataPortalENSG00000162951
TCGA cBioPortalLRRTM1
AceView (NCBI)LRRTM1
Genatlas (Paris)LRRTM1
WikiGenes347730
SOURCE (Princeton)LRRTM1
Genetics Home Reference (NIH)LRRTM1
Genomic and cartography
GoldenPath hg38 (UCSC)LRRTM1  -     chr2:80301878-80304362 -  2p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRTM1  -     2p12   [Description]    (hg19-Feb_2009)
EnsemblLRRTM1 - 2p12 [CytoView hg19]  LRRTM1 - 2p12 [CytoView hg38]
Mapping of homologs : NCBILRRTM1 [Mapview hg19]  LRRTM1 [Mapview hg38]
OMIM610867   
Gene and transcription
Genbank (Entrez)AA977181 AK056644 AK225779 AK290512 AY182024
RefSeq transcript (Entrez)NM_178839
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRTM1
Cluster EST : UnigeneHs.591580 [ NCBI ]
CGAP (NCI)Hs.591580
Alternative Splicing GalleryENSG00000162951
Gene ExpressionLRRTM1 [ NCBI-GEO ]   LRRTM1 [ EBI - ARRAY_EXPRESS ]   LRRTM1 [ SEEK ]   LRRTM1 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRTM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)347730
GTEX Portal (Tissue expression)LRRTM1
Human Protein AtlasENSG00000162951-LRRTM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UE6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UE6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UE6
Splice isoforms : SwissVarQ86UE6
PhosPhoSitePlusQ86UE6
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  
Conserved Domain (NCBI)LRRTM1
DMDM Disease mutations347730
Blocks (Seattle)LRRTM1
SuperfamilyQ86UE6
Human Protein Atlas [tissue]ENSG00000162951-LRRTM1 [tissue]
Peptide AtlasQ86UE6
HPRD14323
IPIIPI00328716   IPI00915860   IPI00916020   IPI00917222   
Protein Interaction databases
DIP (DOE-UCLA)Q86UE6
IntAct (EBI)Q86UE6
FunCoupENSG00000162951
BioGRIDLRRTM1
STRING (EMBL)LRRTM1
ZODIACLRRTM1
Ontologies - Pathways
QuickGOQ86UE6
Ontology : AmiGOnegative regulation of receptor internalization  molecular_function  protein kinase inhibitor activity  endoplasmic reticulum  negative regulation of protein kinase activity  locomotory behavior  biological_process  cell surface  integral component of membrane  cytokine-mediated signaling pathway  cell junction  axon  growth cone  protein localization to synapse  exploration behavior  postsynaptic membrane  negative regulation of JAK-STAT cascade  synapse organization  positive regulation of synapse assembly  excitatory synapse  long-term synaptic potentiation  
Ontology : EGO-EBInegative regulation of receptor internalization  molecular_function  protein kinase inhibitor activity  endoplasmic reticulum  negative regulation of protein kinase activity  locomotory behavior  biological_process  cell surface  integral component of membrane  cytokine-mediated signaling pathway  cell junction  axon  growth cone  protein localization to synapse  exploration behavior  postsynaptic membrane  negative regulation of JAK-STAT cascade  synapse organization  positive regulation of synapse assembly  excitatory synapse  long-term synaptic potentiation  
NDEx NetworkLRRTM1
Atlas of Cancer Signalling NetworkLRRTM1
Wikipedia pathwaysLRRTM1
Orthology - Evolution
OrthoDB347730
GeneTree (enSembl)ENSG00000162951
Phylogenetic Trees/Animal Genes : TreeFamLRRTM1
HOVERGENQ86UE6
HOGENOMQ86UE6
Homologs : HomoloGeneLRRTM1
Homology/Alignments : Family Browser (UCSC)LRRTM1
Gene fusions - Rearrangements
Fusion: Tumor Portal LRRTM1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRTM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRTM1
dbVarLRRTM1
ClinVarLRRTM1
1000_GenomesLRRTM1 
Exome Variant ServerLRRTM1
ExAC (Exome Aggregation Consortium)ENSG00000162951
GNOMAD BrowserENSG00000162951
Genetic variants : HAPMAP347730
Genomic Variants (DGV)LRRTM1 [DGVbeta]
DECIPHERLRRTM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRTM1 
Mutations
ICGC Data PortalLRRTM1 
TCGA Data PortalLRRTM1 
Broad Tumor PortalLRRTM1
OASIS PortalLRRTM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRTM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRTM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LRRTM1
DgiDB (Drug Gene Interaction Database)LRRTM1
DoCM (Curated mutations)LRRTM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRTM1 (select a term)
intoGenLRRTM1
Cancer3DLRRTM1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610867   
Orphanet
MedgenLRRTM1
Genetic Testing Registry LRRTM1
NextProtQ86UE6 [Medical]
TSGene347730
GENETestsLRRTM1
Target ValidationLRRTM1
Huge Navigator LRRTM1 [HugePedia]
snp3D : Map Gene to Disease347730
BioCentury BCIQLRRTM1
ClinGenLRRTM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD347730
Chemical/Pharm GKB GenePA134887293
Clinical trialLRRTM1
Miscellaneous
canSAR (ICR)LRRTM1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRTM1
EVEXLRRTM1
GoPubMedLRRTM1
iHOP/TD>,T>LRRTM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:11:49 CET 2017

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