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LRRTM3 (leucine rich repeat transmembrane neuronal 3)

Identity

Other alias-
HGNC (Hugo) LRRTM3
LocusID (NCBI) 347731
Atlas_Id 68673
Location 10q21.3  [Link to chromosome band 10q21]
Location_base_pair Starts at 66926034 and ends at 67101551 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADK (10q22.2) / LRRTM3 (10q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRTM3   19410
Cards
Entrez_Gene (NCBI)LRRTM3  347731  leucine rich repeat transmembrane neuronal 3
Aliases
GeneCards (Weizmann)LRRTM3
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr10:66926034-67101551 [Contig_View]  LRRTM3 [Vega]
TCGA cBioPortalLRRTM3
AceView (NCBI)LRRTM3
Genatlas (Paris)LRRTM3
WikiGenes347731
SOURCE (Princeton)LRRTM3
Genetics Home Reference (NIH)LRRTM3
Genomic and cartography
GoldenPath hg38 (UCSC)LRRTM3  -     chr10:66926034-67101551 +  10q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRTM3  -     10q21.3   [Description]    (hg19-Feb_2009)
EnsemblLRRTM3 - 10q21.3 [CytoView hg19]  LRRTM3 - 10q21.3 [CytoView hg38]
Mapping of homologs : NCBILRRTM3 [Mapview hg19]  LRRTM3 [Mapview hg38]
OMIM610869   
Gene and transcription
Genbank (Entrez)AK290168 AK294029 AY182028 AY358315 BC111492
RefSeq transcript (Entrez)NM_178011
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRTM3
Cluster EST : UnigeneHs.712279 [ NCBI ]
CGAP (NCI)Hs.712279
Gene ExpressionLRRTM3 [ NCBI-GEO ]   LRRTM3 [ EBI - ARRAY_EXPRESS ]   LRRTM3 [ SEEK ]   LRRTM3 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRTM3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)347731
GTEX Portal (Tissue expression)LRRTM3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86VH5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86VH5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86VH5
Splice isoforms : SwissVarQ86VH5
PhosPhoSitePlusQ86VH5
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)LRR_1 (PF00560)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam00560    pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRNT (SM00013)  
Conserved Domain (NCBI)LRRTM3
DMDM Disease mutations347731
Blocks (Seattle)LRRTM3
SuperfamilyQ86VH5
Peptide AtlasQ86VH5
HPRD14324
IPIIPI00179801   IPI00607819   
Protein Interaction databases
DIP (DOE-UCLA)Q86VH5
IntAct (EBI)Q86VH5
BioGRIDLRRTM3
STRING (EMBL)LRRTM3
ZODIACLRRTM3
Ontologies - Pathways
QuickGOQ86VH5
Ontology : AmiGOprotein kinase inhibitor activity  cytoplasm  negative regulation of protein kinase activity  integral component of membrane  cytokine-mediated signaling pathway  cell junction  postsynaptic membrane  negative regulation of JAK-STAT cascade  positive regulation of synapse assembly  positive regulation of beta-amyloid formation  
Ontology : EGO-EBIprotein kinase inhibitor activity  cytoplasm  negative regulation of protein kinase activity  integral component of membrane  cytokine-mediated signaling pathway  cell junction  postsynaptic membrane  negative regulation of JAK-STAT cascade  positive regulation of synapse assembly  positive regulation of beta-amyloid formation  
NDEx NetworkLRRTM3
Atlas of Cancer Signalling NetworkLRRTM3
Wikipedia pathwaysLRRTM3
Orthology - Evolution
OrthoDB347731
Phylogenetic Trees/Animal Genes : TreeFamLRRTM3
HOVERGENQ86VH5
HOGENOMQ86VH5
Homologs : HomoloGeneLRRTM3
Homology/Alignments : Family Browser (UCSC)LRRTM3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRTM3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRTM3
dbVarLRRTM3
ClinVarLRRTM3
1000_GenomesLRRTM3 
Exome Variant ServerLRRTM3
ExAC (Exome Aggregation Consortium)LRRTM3 (select the gene name)
Genetic variants : HAPMAP347731
Genomic Variants (DGV)LRRTM3 [DGVbeta]
DECIPHERLRRTM3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRTM3 
Mutations
ICGC Data PortalLRRTM3 
TCGA Data PortalLRRTM3 
Broad Tumor PortalLRRTM3
OASIS PortalLRRTM3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRTM3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRRTM3
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LRRTM3
DgiDB (Drug Gene Interaction Database)LRRTM3
DoCM (Curated mutations)LRRTM3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRTM3 (select a term)
intoGenLRRTM3
Cancer3DLRRTM3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610869   
Orphanet
MedgenLRRTM3
Genetic Testing Registry LRRTM3
NextProtQ86VH5 [Medical]
TSGene347731
GENETestsLRRTM3
Target ValidationLRRTM3
Huge Navigator LRRTM3 [HugePedia]
snp3D : Map Gene to Disease347731
BioCentury BCIQLRRTM3
ClinGenLRRTM3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD347731
Chemical/Pharm GKB GenePA134962991
Clinical trialLRRTM3
Miscellaneous
canSAR (ICR)LRRTM3 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRTM3
EVEXLRRTM3
GoPubMedLRRTM3
iHOPLRRTM3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:26:38 CEST 2017

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