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LRRTM3 (leucine rich repeat transmembrane neuronal 3)

Identity

Other alias-
HGNC (Hugo) LRRTM3
LocusID (NCBI) 347731
Atlas_Id 68673
Location 10q21.3  [Link to chromosome band 10q21]
Location_base_pair Starts at 66926034 and ends at 67101551 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADK (10q22.2) / LRRTM3 (10q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRRTM3   19410
Cards
Entrez_Gene (NCBI)LRRTM3  347731  leucine rich repeat transmembrane neuronal 3
Aliases
GeneCards (Weizmann)LRRTM3
Ensembl hg19 (Hinxton)ENSG00000198739 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198739 [Gene_View]  ENSG00000198739 [Sequence]  chr10:66926034-67101551 [Contig_View]  LRRTM3 [Vega]
ICGC DataPortalENSG00000198739
TCGA cBioPortalLRRTM3
AceView (NCBI)LRRTM3
Genatlas (Paris)LRRTM3
WikiGenes347731
SOURCE (Princeton)LRRTM3
Genetics Home Reference (NIH)LRRTM3
Genomic and cartography
GoldenPath hg38 (UCSC)LRRTM3  -     chr10:66926034-67101551 +  10q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRRTM3  -     10q21.3   [Description]    (hg19-Feb_2009)
GoldenPathLRRTM3 - 10q21.3 [CytoView hg19]  LRRTM3 - 10q21.3 [CytoView hg38]
ImmunoBaseENSG00000198739
Mapping of homologs : NCBILRRTM3 [Mapview hg19]  LRRTM3 [Mapview hg38]
OMIM610869   
Gene and transcription
Genbank (Entrez)AK290168 AK294029 AY182028 AY358315 BC111492
RefSeq transcript (Entrez)NM_178011
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRRTM3
Cluster EST : UnigeneHs.712279 [ NCBI ]
CGAP (NCI)Hs.712279
Alternative Splicing GalleryENSG00000198739
Gene ExpressionLRRTM3 [ NCBI-GEO ]   LRRTM3 [ EBI - ARRAY_EXPRESS ]   LRRTM3 [ SEEK ]   LRRTM3 [ MEM ]
Gene Expression Viewer (FireBrowse)LRRTM3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)347731
GTEX Portal (Tissue expression)LRRTM3
Human Protein AtlasENSG00000198739-LRRTM3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86VH5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86VH5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86VH5
Splice isoforms : SwissVarQ86VH5
PhosPhoSitePlusQ86VH5
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR_dom_sf    LRRNT   
Domain families : Pfam (Sanger)LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRNT (SM00013)  
Conserved Domain (NCBI)LRRTM3
DMDM Disease mutations347731
Blocks (Seattle)LRRTM3
SuperfamilyQ86VH5
Human Protein Atlas [tissue]ENSG00000198739-LRRTM3 [tissue]
Peptide AtlasQ86VH5
HPRD14324
IPIIPI00179801   IPI00607819   
Protein Interaction databases
DIP (DOE-UCLA)Q86VH5
IntAct (EBI)Q86VH5
FunCoupENSG00000198739
BioGRIDLRRTM3
STRING (EMBL)LRRTM3
ZODIACLRRTM3
Ontologies - Pathways
QuickGOQ86VH5
Ontology : AmiGOextracellular space  cell junction  extracellular matrix  positive regulation of synapse assembly  glutamatergic synapse  glutamatergic synapse  presynapse assembly  presynapse assembly  integral component of postsynaptic density membrane  positive regulation of amyloid-beta formation  
Ontology : EGO-EBIextracellular space  cell junction  extracellular matrix  positive regulation of synapse assembly  glutamatergic synapse  glutamatergic synapse  presynapse assembly  presynapse assembly  integral component of postsynaptic density membrane  positive regulation of amyloid-beta formation  
NDEx NetworkLRRTM3
Atlas of Cancer Signalling NetworkLRRTM3
Wikipedia pathwaysLRRTM3
Orthology - Evolution
OrthoDB347731
GeneTree (enSembl)ENSG00000198739
Phylogenetic Trees/Animal Genes : TreeFamLRRTM3
HOGENOMQ86VH5
Homologs : HomoloGeneLRRTM3
Homology/Alignments : Family Browser (UCSC)LRRTM3
Gene fusions - Rearrangements
Fusion : QuiverLRRTM3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRRTM3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRRTM3
dbVarLRRTM3
ClinVarLRRTM3
1000_GenomesLRRTM3 
Exome Variant ServerLRRTM3
ExAC (Exome Aggregation Consortium)ENSG00000198739
GNOMAD BrowserENSG00000198739
Varsome BrowserLRRTM3
Genetic variants : HAPMAP347731
Genomic Variants (DGV)LRRTM3 [DGVbeta]
DECIPHERLRRTM3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRRTM3 
Mutations
ICGC Data PortalLRRTM3 
TCGA Data PortalLRRTM3 
Broad Tumor PortalLRRTM3
OASIS PortalLRRTM3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRRTM3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLRRTM3
Mutations and Diseases : HGMDLRRTM3
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch LRRTM3
DgiDB (Drug Gene Interaction Database)LRRTM3
DoCM (Curated mutations)LRRTM3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRRTM3 (select a term)
intoGenLRRTM3
Cancer3DLRRTM3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610869   
Orphanet
DisGeNETLRRTM3
MedgenLRRTM3
Genetic Testing Registry LRRTM3
NextProtQ86VH5 [Medical]
TSGene347731
GENETestsLRRTM3
Target ValidationLRRTM3
Huge Navigator LRRTM3 [HugePedia]
snp3D : Map Gene to Disease347731
BioCentury BCIQLRRTM3
ClinGenLRRTM3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD347731
Chemical/Pharm GKB GenePA134962991
Clinical trialLRRTM3
Miscellaneous
canSAR (ICR)LRRTM3 (select the gene name)
DataMed IndexLRRTM3
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRRTM3
EVEXLRRTM3
GoPubMedLRRTM3
iHOPLRRTM3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Sep 3 15:51:17 CEST 2019

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