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LRTM2 (leucine rich repeats and transmembrane domains 2)

Identity

Other alias-
HGNC (Hugo) LRTM2
LocusID (NCBI) 654429
Atlas_Id 68677
Location 12p13.33  [Link to chromosome band 12p13]
Location_base_pair Starts at 1820267 and ends at 1836752 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRTM2   32443
Cards
Entrez_Gene (NCBI)LRTM2  654429  leucine rich repeats and transmembrane domains 2
Aliases
GeneCards (Weizmann)LRTM2
Ensembl hg19 (Hinxton)ENSG00000166159 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166159 [Gene_View]  chr12:1820267-1836752 [Contig_View]  LRTM2 [Vega]
ICGC DataPortalENSG00000166159
TCGA cBioPortalLRTM2
AceView (NCBI)LRTM2
Genatlas (Paris)LRTM2
WikiGenes654429
SOURCE (Princeton)LRTM2
Genetics Home Reference (NIH)LRTM2
Genomic and cartography
GoldenPath hg38 (UCSC)LRTM2  -     chr12:1820267-1836752 +  12p13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRTM2  -     12p13.33   [Description]    (hg19-Feb_2009)
EnsemblLRTM2 - 12p13.33 [CytoView hg19]  LRTM2 - 12p13.33 [CytoView hg38]
Mapping of homologs : NCBILRTM2 [Mapview hg19]  LRTM2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK095610 AK124687 AK125402 AK126866 BC036868
RefSeq transcript (Entrez)NM_001039029 NM_001163925 NM_001163926
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRTM2
Cluster EST : UnigeneHs.585579 [ NCBI ]
CGAP (NCI)Hs.585579
Alternative Splicing GalleryENSG00000166159
Gene ExpressionLRTM2 [ NCBI-GEO ]   LRTM2 [ EBI - ARRAY_EXPRESS ]   LRTM2 [ SEEK ]   LRTM2 [ MEM ]
Gene Expression Viewer (FireBrowse)LRTM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)654429
GTEX Portal (Tissue expression)LRTM2
Human Protein AtlasENSG00000166159-LRTM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N967   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N967  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N967
Splice isoforms : SwissVarQ8N967
PhosPhoSitePlusQ8N967
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Cys-rich_flank_reg_C    L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)LRR_8 (PF13855)    LRRNT (PF01462)   
Domain families : Pfam (NCBI)pfam13855    pfam01462   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRCT (SM00082)  LRRNT (SM00013)  
Conserved Domain (NCBI)LRTM2
DMDM Disease mutations654429
Blocks (Seattle)LRTM2
SuperfamilyQ8N967
Human Protein Atlas [tissue]ENSG00000166159-LRTM2 [tissue]
Peptide AtlasQ8N967
IPIIPI00167619   IPI00445771   IPI01014216   IPI01013267   
Protein Interaction databases
DIP (DOE-UCLA)Q8N967
IntAct (EBI)Q8N967
FunCoupENSG00000166159
BioGRIDLRTM2
STRING (EMBL)LRTM2
ZODIACLRTM2
Ontologies - Pathways
QuickGOQ8N967
Ontology : AmiGOprotein kinase inhibitor activity  cytoplasm  negative regulation of protein kinase activity  integral component of membrane  cytokine-mediated signaling pathway  negative regulation of JAK-STAT cascade  positive regulation of synapse assembly  
Ontology : EGO-EBIprotein kinase inhibitor activity  cytoplasm  negative regulation of protein kinase activity  integral component of membrane  cytokine-mediated signaling pathway  negative regulation of JAK-STAT cascade  positive regulation of synapse assembly  
NDEx NetworkLRTM2
Atlas of Cancer Signalling NetworkLRTM2
Wikipedia pathwaysLRTM2
Orthology - Evolution
OrthoDB654429
GeneTree (enSembl)ENSG00000166159
Phylogenetic Trees/Animal Genes : TreeFamLRTM2
HOVERGENQ8N967
HOGENOMQ8N967
Homologs : HomoloGeneLRTM2
Homology/Alignments : Family Browser (UCSC)LRTM2
Gene fusions - Rearrangements
Tumor Fusion PortalLRTM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRTM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRTM2
dbVarLRTM2
ClinVarLRTM2
1000_GenomesLRTM2 
Exome Variant ServerLRTM2
ExAC (Exome Aggregation Consortium)ENSG00000166159
GNOMAD BrowserENSG00000166159
Genetic variants : HAPMAP654429
Genomic Variants (DGV)LRTM2 [DGVbeta]
DECIPHERLRTM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRTM2 
Mutations
ICGC Data PortalLRTM2 
TCGA Data PortalLRTM2 
Broad Tumor PortalLRTM2
OASIS PortalLRTM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRTM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRTM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LRTM2
DgiDB (Drug Gene Interaction Database)LRTM2
DoCM (Curated mutations)LRTM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRTM2 (select a term)
intoGenLRTM2
Cancer3DLRTM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETLRTM2
MedgenLRTM2
Genetic Testing Registry LRTM2
NextProtQ8N967 [Medical]
TSGene654429
GENETestsLRTM2
Target ValidationLRTM2
Huge Navigator LRTM2 [HugePedia]
snp3D : Map Gene to Disease654429
BioCentury BCIQLRTM2
ClinGenLRTM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD654429
Chemical/Pharm GKB GenePA142671500
Clinical trialLRTM2
Miscellaneous
canSAR (ICR)LRTM2 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRTM2
EVEXLRTM2
GoPubMedLRTM2
iHOPLRTM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:26:45 CET 2017

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