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LRWD1 (leucine rich repeats and WD repeat domain containing 1)

Identity

Other aliasCENP-33
ORCA
HGNC (Hugo) LRWD1
LocusID (NCBI) 222229
Atlas_Id 56845
Location 7q22.1  [Link to chromosome band 7q22]
Location_base_pair Starts at 102464883 and ends at 102473168 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ELL3 (15q15.3) / LRWD1 (7q22.1)LRWD1 (7q22.1) / CRLF1 (19p13.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LRWD1   21769
Cards
Entrez_Gene (NCBI)LRWD1  222229  leucine rich repeats and WD repeat domain containing 1
AliasesCENP-33; ORCA
GeneCards (Weizmann)LRWD1
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr7:102464883-102473168 [Contig_View]  LRWD1 [Vega]
TCGA cBioPortalLRWD1
AceView (NCBI)LRWD1
Genatlas (Paris)LRWD1
WikiGenes222229
SOURCE (Princeton)LRWD1
Genetics Home Reference (NIH)LRWD1
Genomic and cartography
GoldenPath hg38 (UCSC)LRWD1  -     chr7:102464883-102473168 +  7q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LRWD1  -     7q22.1   [Description]    (hg19-Feb_2009)
EnsemblLRWD1 - 7q22.1 [CytoView hg19]  LRWD1 - 7q22.1 [CytoView hg38]
Mapping of homologs : NCBILRWD1 [Mapview hg19]  LRWD1 [Mapview hg38]
OMIM615167   
Gene and transcription
Genbank (Entrez)AB209379 AK290967 AK313771 AL133057 BC009436
RefSeq transcript (Entrez)NM_001317721 NM_152892
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LRWD1
Cluster EST : UnigeneHs.274135 [ NCBI ]
CGAP (NCI)Hs.274135
Gene ExpressionLRWD1 [ NCBI-GEO ]   LRWD1 [ EBI - ARRAY_EXPRESS ]   LRWD1 [ SEEK ]   LRWD1 [ MEM ]
Gene Expression Viewer (FireBrowse)LRWD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)222229
GTEX Portal (Tissue expression)LRWD1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UFC0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UFC0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UFC0
Splice isoforms : SwissVarQ9UFC0
PhosPhoSitePlusQ9UFC0
Domaine pattern : Prosite (Expaxy)LRR (PS51450)    WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    Leu-rich_rpt_4    Leu-rich_rpt_typical-subtyp    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)LRR_4 (PF12799)   
Domain families : Pfam (NCBI)pfam12799   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  WD40 (SM00320)  
Conserved Domain (NCBI)LRWD1
DMDM Disease mutations222229
Blocks (Seattle)LRWD1
SuperfamilyQ9UFC0
Peptide AtlasQ9UFC0
IPIIPI00069309   IPI00555865   IPI00945660   IPI00946148   IPI00944967   IPI00946381   IPI00945971   IPI00945271   
Protein Interaction databases
DIP (DOE-UCLA)Q9UFC0
IntAct (EBI)Q9UFC0
BioGRIDLRWD1
STRING (EMBL)LRWD1
ZODIACLRWD1
Ontologies - Pathways
QuickGOQ9UFC0
Ontology : AmiGOkinetochore  condensed chromosome kinetochore  chromatin binding  protein binding  nucleus  nucleoplasm  nuclear origin of replication recognition complex  pericentric heterochromatin  nucleolus  microtubule organizing center  cytosol  DNA replication initiation  chromatin organization  methyl-CpG binding  covalent chromatin modification  telomeric heterochromatin  methylated histone binding  establishment of protein localization to chromatin  
Ontology : EGO-EBIkinetochore  condensed chromosome kinetochore  chromatin binding  protein binding  nucleus  nucleoplasm  nuclear origin of replication recognition complex  pericentric heterochromatin  nucleolus  microtubule organizing center  cytosol  DNA replication initiation  chromatin organization  methyl-CpG binding  covalent chromatin modification  telomeric heterochromatin  methylated histone binding  establishment of protein localization to chromatin  
NDEx NetworkLRWD1
Atlas of Cancer Signalling NetworkLRWD1
Wikipedia pathwaysLRWD1
Orthology - Evolution
OrthoDB222229
Phylogenetic Trees/Animal Genes : TreeFamLRWD1
HOVERGENQ9UFC0
HOGENOMQ9UFC0
Homologs : HomoloGeneLRWD1
Homology/Alignments : Family Browser (UCSC)LRWD1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLRWD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LRWD1
dbVarLRWD1
ClinVarLRWD1
1000_GenomesLRWD1 
Exome Variant ServerLRWD1
ExAC (Exome Aggregation Consortium)LRWD1 (select the gene name)
Genetic variants : HAPMAP222229
Genomic Variants (DGV)LRWD1 [DGVbeta]
DECIPHERLRWD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLRWD1 
Mutations
ICGC Data PortalLRWD1 
TCGA Data PortalLRWD1 
Broad Tumor PortalLRWD1
OASIS PortalLRWD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLRWD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLRWD1
BioMutasearch LRWD1
DgiDB (Drug Gene Interaction Database)LRWD1
DoCM (Curated mutations)LRWD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LRWD1 (select a term)
intoGenLRWD1
Cancer3DLRWD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615167   
Orphanet
MedgenLRWD1
Genetic Testing Registry LRWD1
NextProtQ9UFC0 [Medical]
TSGene222229
GENETestsLRWD1
Target ValidationLRWD1
Huge Navigator LRWD1 [HugePedia]
snp3D : Map Gene to Disease222229
BioCentury BCIQLRWD1
ClinGenLRWD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD222229
Chemical/Pharm GKB GenePA162394694
Clinical trialLRWD1
Miscellaneous
canSAR (ICR)LRWD1 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLRWD1
EVEXLRWD1
GoPubMedLRWD1
iHOPLRWD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:58:19 CEST 2017

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