| Nomenclature |
HGNC (Hugo) | LSM2 13940 |
| Cards |
Entrez_Gene (NCBI) | LSM2 57819 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated |
Aliases | C6orf28; G7B; YBL026W; snRNP |
GeneCards (Weizmann) | LSM2 |
Ensembl hg19 (Hinxton) | ENSG00000204392 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000204392 [Gene_View]  ENSG00000204392 [Sequence] chr6:31797392-31806984 [Contig_View] LSM2 [Vega] |
ICGC DataPortal | ENSG00000204392 |
TCGA cBioPortal | LSM2 |
AceView (NCBI) | LSM2 |
Genatlas (Paris) | LSM2 |
WikiGenes | 57819 |
SOURCE (Princeton) | LSM2 |
Genetics Home Reference (NIH) | LSM2 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | LSM2 - chr6:31797392-31806984 - 6p21.33 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | LSM2 - 6p21.33 [Description] (hg19-Feb_2009) |
GoldenPath | LSM2 - 6p21.33 [CytoView hg19] LSM2 - 6p21.33 [CytoView hg38] |
ImmunoBase | ENSG00000204392 |
Mapping of homologs : NCBI | LSM2 [Mapview hg19] LSM2 [Mapview hg38] |
OMIM | 607282 |
| Gene and transcription |
Genbank (Entrez) | AF136977 AF182288 AF196468 AI570628 AJ245416 |
RefSeq transcript (Entrez) | NM_021177 |
RefSeq genomic (Entrez) | NC_000006 NT_113891 NT_167244 NT_167245 NT_167247 NT_167248 |
Consensus coding sequences : CCDS (NCBI) | LSM2 |
Cluster EST : Unigene | Hs.103106 [ NCBI ] |
CGAP (NCI) | Hs.103106 |
Alternative Splicing Gallery | ENSG00000204392 |
Gene Expression | LSM2 [ NCBI-GEO ] LSM2 [ EBI - ARRAY_EXPRESS ]
LSM2 [ SEEK ] LSM2 [ MEM ] |
Gene Expression Viewer (FireBrowse) | LSM2 [ Firebrowse - Broad ] |
SOURCE (Princeton) | Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60] |
Genevestigator | Expression in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 57819 |
GTEX Portal (Tissue expression) | LSM2 |
Human Protein Atlas | ENSG00000204392-LSM2 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q9Y333 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q9Y333 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q9Y333 |
Splice isoforms : SwissVar | Q9Y333 |
PhosPhoSitePlus | Q9Y333 |
Domains : Interpro (EBI) | LSM_dom_euk/arc LSM_dom_sf U6_snRNA_Lsm2 |
Domain families : Pfam (Sanger) | LSM (PF01423) |
Domain families : Pfam (NCBI) | pfam01423 |
Domain families : Smart (EMBL) | Sm (SM00651) |
Conserved Domain (NCBI) | LSM2 |
DMDM Disease mutations | 57819 |
Blocks (Seattle) | LSM2 |
PDB (RSDB) | 3JCR 5O9Z |
PDB Europe | 3JCR 5O9Z |
PDB (PDBSum) | 3JCR 5O9Z |
PDB (IMB) | 3JCR 5O9Z |
Structural Biology KnowledgeBase | 3JCR 5O9Z |
SCOP (Structural Classification of Proteins) | 3JCR 5O9Z |
CATH (Classification of proteins structures) | 3JCR 5O9Z |
Superfamily | Q9Y333 |
Human Protein Atlas [tissue] | ENSG00000204392-LSM2 [tissue] |
Peptide Atlas | Q9Y333 |
HPRD | 06282 |
IPI | IPI00032460 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q9Y333 |
IntAct (EBI) | Q9Y333 |
FunCoup | ENSG00000204392 |
BioGRID | LSM2 |
STRING (EMBL) | LSM2 |
ZODIAC | LSM2 |
| Ontologies - Pathways |
QuickGO | Q9Y333 |
Ontology : AmiGO | mRNA splicing, via spliceosome mRNA splicing, via spliceosome mRNA splicing, via spliceosome P-body RNA binding RNA binding protein binding nucleus nucleoplasm U6 snRNP cytosol U6 snRNA binding Ral GTPase binding exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay U4/U6 x U5 tri-snRNP complex U4/U6 x U5 tri-snRNP complex U2-type precatalytic spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome Lsm2-8 complex Lsm1-7-Pat1 complex |
Ontology : EGO-EBI | mRNA splicing, via spliceosome mRNA splicing, via spliceosome mRNA splicing, via spliceosome P-body RNA binding RNA binding protein binding nucleus nucleoplasm U6 snRNP cytosol U6 snRNA binding Ral GTPase binding exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay U4/U6 x U5 tri-snRNP complex U4/U6 x U5 tri-snRNP complex U2-type precatalytic spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome Lsm2-8 complex Lsm1-7-Pat1 complex |
Pathways : KEGG | RNA degradation Spliceosome |
NDEx Network | LSM2 |
Atlas of Cancer Signalling Network | LSM2 |
Wikipedia pathways | LSM2 |
| Orthology - Evolution |
OrthoDB | 57819 |
GeneTree (enSembl) | ENSG00000204392 |
Phylogenetic Trees/Animal Genes : TreeFam | LSM2 |
HOGENOM | Q9Y333 |
Homologs : HomoloGene | LSM2 |
Homology/Alignments : Family Browser (UCSC) | LSM2 |
| Gene fusions - Rearrangements |
Fusion : Quiver | LSM2 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | LSM2 [hg38] |
dbSNP Single Nucleotide Polymorphism (NCBI) | LSM2 |
dbVar | LSM2 |
ClinVar | LSM2 |
1000_Genomes | LSM2 |
Exome Variant Server | LSM2 |
ExAC (Exome Aggregation Consortium) | ENSG00000204392 |
GNOMAD Browser | ENSG00000204392 |
Varsome Browser | LSM2 |
Genetic variants : HAPMAP | 57819 |
Genomic Variants (DGV) | LSM2 [DGVbeta] |
DECIPHER | LSM2 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | LSM2 |
| Mutations |
ICGC Data Portal | LSM2 |
TCGA Data Portal | LSM2 |
Broad Tumor Portal | LSM2 |
OASIS Portal | LSM2 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | LSM2 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | LSM2 |
Mutations and Diseases : HGMD | LSM2 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search LSM2 |
DgiDB (Drug Gene Interaction Database) | LSM2 |
DoCM (Curated mutations) | LSM2 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | LSM2 (select a term) |
intoGen | LSM2 |
Cancer3D | LSM2(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 607282 |
Orphanet | |
DisGeNET | LSM2 |
Medgen | LSM2 |
Genetic Testing Registry | LSM2
|
NextProt | Q9Y333 [Medical] |
TSGene | 57819 |
GENETests | LSM2 |
Target Validation | LSM2 |
Huge Navigator |
LSM2 [HugePedia] |
snp3D : Map Gene to Disease | 57819 |
BioCentury BCIQ | LSM2 |
ClinGen | LSM2 |
| Clinical trials, drugs, therapy |
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Chemical/Protein Interactions : CTD | 57819 |
Chemical/Pharm GKB Gene | PA25929 |
Clinical trial | LSM2 |
| Miscellaneous |
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canSAR (ICR) | LSM2 (select the gene name) |
DataMed Index | LSM2 |
| Probes |
---|
| Litterature |
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PubMed | 55 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
CoreMine | LSM2 |
EVEX | LSM2 |
GoPubMed | LSM2 |
iHOP | LSM2 |