| Nomenclature |
|---|
| HGNC (Hugo) | LSM2 13940 |
| Cards |
|---|
| Entrez_Gene (NCBI) | LSM2 57819 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated |
| Aliases | C6orf28; G7B; YBL026W; snRNP |
| GeneCards (Weizmann) | LSM2 |
| Ensembl hg19 (Hinxton) | ENSG00000204392 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000204392 [Gene_View] ENSG00000204392 [Sequence] chr6:31797392-31806984 [Contig_View] LSM2 [Vega] |
| ICGC DataPortal | ENSG00000204392 |
| TCGA cBioPortal | LSM2 |
| AceView (NCBI) | LSM2 |
| Genatlas (Paris) | LSM2 |
| WikiGenes | 57819 |
| SOURCE (Princeton) | LSM2 |
| Genetics Home Reference (NIH) | LSM2 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | LSM2 - chr6:31797392-31806984 - 6p21.33 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | LSM2 - 6p21.33 [Description] (hg19-Feb_2009) |
LSM2 - 6p21.33 [CytoView hg19] LSM2 - 6p21.33 [CytoView hg38] |
| Mapping of homologs : NCBI | LSM2 [Mapview hg19] LSM2 [Mapview hg38] |
| OMIM | 607282 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF136977 AF182288 AF196468 AI570628 AJ245416 |
| RefSeq transcript (Entrez) | NM_021177 |
| RefSeq genomic (Entrez) | NC_000006 NT_113891 NT_167244 NT_167245 NT_167247 NT_167248 |
| Consensus coding sequences : CCDS (NCBI) | LSM2 |
| Cluster EST : Unigene | Hs.103106 [ NCBI ] |
| CGAP (NCI) | Hs.103106 |
| Alternative Splicing Gallery | ENSG00000204392 |
| Gene Expression | LSM2 [ NCBI-GEO ] LSM2 [ EBI - ARRAY_EXPRESS ]
LSM2 [ SEEK ] LSM2 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | LSM2 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 57819 |
| GTEX Portal (Tissue expression) | LSM2 |
| Human Protein Atlas | ENSG00000204392-LSM2 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q9Y333 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q9Y333 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q9Y333 |
| Splice isoforms : SwissVar | Q9Y333 |
| PhosPhoSitePlus | Q9Y333 |
| Domains : Interpro (EBI) | LSM_dom_euk/arc LSM_dom_sf U6_snRNA_Lsm2 |
| Domain families : Pfam (Sanger) | LSM (PF01423) |
| Domain families : Pfam (NCBI) | pfam01423 |
| Domain families : Smart (EMBL) | Sm (SM00651) |
| Conserved Domain (NCBI) | LSM2 |
| DMDM Disease mutations | 57819 |
| Blocks (Seattle) | LSM2 |
| PDB (RSDB) | 3JCR 5O9Z |
| PDB Europe | 3JCR 5O9Z |
| PDB (PDBSum) | 3JCR 5O9Z |
| PDB (IMB) | 3JCR 5O9Z |
| Structural Biology KnowledgeBase | 3JCR 5O9Z |
| SCOP (Structural Classification of Proteins) | 3JCR 5O9Z |
| CATH (Classification of proteins structures) | 3JCR 5O9Z |
| Superfamily | Q9Y333 |
| Human Protein Atlas [tissue] | ENSG00000204392-LSM2 [tissue] |
| Peptide Atlas | Q9Y333 |
| HPRD | 06282 |
| IPI | IPI00032460 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q9Y333 |
| IntAct (EBI) | Q9Y333 |
| FunCoup | ENSG00000204392 |
| BioGRID | LSM2 |
| STRING (EMBL) | LSM2 |
| ZODIAC | LSM2 |
| Ontologies - Pathways |
|---|
| QuickGO | Q9Y333 |
| Ontology : AmiGO | mRNA splicing, via spliceosome mRNA splicing, via spliceosome mRNA splicing, via spliceosome P-body RNA binding RNA binding protein binding nucleus nucleoplasm U6 snRNP cytosol U6 snRNA binding Ral GTPase binding exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay U4/U6 x U5 tri-snRNP complex U4/U6 x U5 tri-snRNP complex U2-type precatalytic spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome Lsm2-8 complex Lsm1-7-Pat1 complex |
| Ontology : EGO-EBI | mRNA splicing, via spliceosome mRNA splicing, via spliceosome mRNA splicing, via spliceosome P-body RNA binding RNA binding protein binding nucleus nucleoplasm U6 snRNP cytosol U6 snRNA binding Ral GTPase binding exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay U4/U6 x U5 tri-snRNP complex U4/U6 x U5 tri-snRNP complex U2-type precatalytic spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome Lsm2-8 complex Lsm1-7-Pat1 complex |
| Pathways : KEGG | RNA degradation Spliceosome |
| NDEx Network | LSM2 |
| Atlas of Cancer Signalling Network | LSM2 |
| Wikipedia pathways | LSM2 |
| Orthology - Evolution |
|---|
| OrthoDB | 57819 |
| GeneTree (enSembl) | ENSG00000204392 |
| Phylogenetic Trees/Animal Genes : TreeFam | LSM2 |
| HOGENOM | Q9Y333 |
| Homologs : HomoloGene | LSM2 |
| Homology/Alignments : Family Browser (UCSC) | LSM2 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | LSM2 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | LSM2 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | LSM2 |
| dbVar | LSM2 |
| ClinVar | LSM2 |
| 1000_Genomes | LSM2 |
| Exome Variant Server | LSM2 |
| ExAC (Exome Aggregation Consortium) | ENSG00000204392 |
| GNOMAD Browser | ENSG00000204392 |
| Varsome Browser | LSM2 |
| Genetic variants : HAPMAP | 57819 |
| Genomic Variants (DGV) | LSM2 [DGVbeta] |
| DECIPHER | LSM2 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | LSM2 |
| Mutations |
|---|
| ICGC Data Portal | LSM2 |
| TCGA Data Portal | LSM2 |
| Broad Tumor Portal | LSM2 |
| OASIS Portal | LSM2 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | LSM2 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | LSM2 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search LSM2 |
| DgiDB (Drug Gene Interaction Database) | LSM2 |
| DoCM (Curated mutations) | LSM2 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | LSM2 (select a term) |
| intoGen | LSM2 |
| Cancer3D | LSM2(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 607282 |
| Orphanet | |
| DisGeNET | LSM2 |
| Medgen | LSM2 |
| Genetic Testing Registry | LSM2
|
| NextProt | Q9Y333 [Medical] |
| TSGene | 57819 |
| GENETests | LSM2 |
| Target Validation | LSM2 |
| Huge Navigator |
LSM2 [HugePedia] |
| snp3D : Map Gene to Disease | 57819 |
| BioCentury BCIQ | LSM2 |
| ClinGen | LSM2 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 57819 |
| Chemical/Pharm GKB Gene | PA25929 |
| Clinical trial | LSM2 |
| Miscellaneous |
|---|
| canSAR (ICR) | LSM2 (select the gene name) |
| DataMed Index | LSM2 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 49 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | LSM2 |
| EVEX | LSM2 |
| GoPubMed | LSM2 |
| iHOP | LSM2 |
