LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated)

2014-11-01  

Identity

HGNC
LOCATION
3p25.1
LOCUSID
ALIAS
SMX4,USS2,YLR438C
FUSION GENES

Other Information

Locus ID:

NCBI: 27258
MIM: 607283
HGNC: 17874
Ensembl: ENSG00000170860

Variants:

dbSNP: 27258
ClinVar: 27258
TCGA: ENSG00000170860
COSMIC: LSM3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170860ENST00000306024P62310

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Spliceosome, U4/U6.U5 tri-snRNPKEGGhsa_M00354
Lsm 2-8 complexKEGGhsa_M00396
Lsm 1-7 complexKEGGhsa_M00397
Spliceosome, U4/U6.U5 tri-snRNPKEGGM00354
Lsm 2-8 complexKEGGM00396
Lsm 1-7 complexKEGGM00397
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163
Deadenylation-dependent mRNA decayREACTOMER-HSA-429914
mRNA decay by 5' to 3' exoribonucleaseREACTOMER-HSA-430039

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
125153822002The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci.181

Citation

Dessen P

LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68687/lsm3